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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei140 – 1401GTPUniRule annotation
Binding sitei144 – 1441GTPUniRule annotation
Binding sitei188 – 1881GTPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi22 – 265GTPUniRule annotation
Nucleotide bindingi109 – 1113GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:LBA0812Imported
OrganismiLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)Imported
Taxonomic identifieri272621 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000006381 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi272621.LBA0812.

Structurei

3D structure databases

ProteinModelPortaliQ5FKU9.
SMRiQ5FKU9. Positions 30-315.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 206193TubulinInterPro annotationAdd
BLAST
Domaini208 – 325118Tubulin_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.
OrthoDBiEOG6S7XZG.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FKU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFTFDSDDN KNAVIKVIGV GGAGGNAVNR MIDDGVQGVS FIAANTDVQA
60 70 80 90 100
LNSNKAENKI QLGPKLTRGL GAGSHPEVGQ KAAEESEQTI EDALKGADMI
110 120 130 140 150
FITAGMGGGT GTGAAPVVAK IARETGALTV GVVTRPFSFE GPKRSKNAAE
160 170 180 190 200
GISQLKQYVD TLVIIANNRL LEMVDKKTPM MDAFKEADNV LKQGVQGISD
210 220 230 240 250
LITSTDYVNL DFADVKTVME NQGAALMGIG RASGENRTVE ATKLAISSPL
260 270 280 290 300
LEVSIDGAKQ VLLNITGGPD LTLFEAQDAS EIVSKAAGDD VNIIFGTSIN
310 320 330 340 350
PNLGDEVVVT VIATGIDSEA EEAASKQLPG RSHQIKAQPK KESEPAQNND
360 370 380 390 400
VVQPKVQTVD RPETIQPENN VSEPEVKKPK QTMVDPTSVW DLNNNQDNQR
410 420 430 440 450
RNTKPAEPEE DSEKFNAFSD QEQEGISQIE TSAQDTSDDN SDIPFFKHRG

EN
Length:452
Mass (Da):48,148
Last modified:March 1, 2005 - v1
Checksum:iF2EF2159C2EB02D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000033 Genomic DNA. Translation: AAV42675.1.
RefSeqiWP_003546805.1. NC_006814.3.
YP_193706.1. NC_006814.3.

Genome annotation databases

EnsemblBacteriaiAAV42675; AAV42675; LBA0812.
GeneIDi3251637.
KEGGilac:LBA0812.
PATRICi22196718. VBILacAci7974_0774.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000033 Genomic DNA. Translation: AAV42675.1.
RefSeqiWP_003546805.1. NC_006814.3.
YP_193706.1. NC_006814.3.

3D structure databases

ProteinModelPortaliQ5FKU9.
SMRiQ5FKU9. Positions 30-315.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272621.LBA0812.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV42675; AAV42675; LBA0812.
GeneIDi3251637.
KEGGilac:LBA0812.
PATRICi22196718. VBILacAci7974_0774.

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.
OrthoDBiEOG6S7XZG.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700396 / NCK56 / N2 / NCFMImported.

Entry informationi

Entry nameiQ5FKU9_LACAC
AccessioniPrimary (citable) accession number: Q5FKU9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: July 6, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.