Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei575UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Enzyme and pathway databases

BioCyciLACI272621:G1G49-1087-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:LBA1092
OrganismiLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Taxonomic identifieri272621 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000006381 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001665981 – 912Phosphoenolpyruvate carboxylaseAdd BLAST912

Proteomic databases

PRIDEiQ5FK38

Interactioni

Protein-protein interaction databases

STRINGi272621.LBA1092

Structurei

3D structure databases

ProteinModelPortaliQ5FK38
SMRiQ5FK38
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5FK38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFTKLENSS DQAVVAEEVK ILTKLLNEST RQLIGDDAFA KIQDLIDTSA
60 70 80 90 100
SKDQKQLESK ISSLNNREMI VVARYFATLP LLINISEDVE LASKVNVFNN
110 120 130 140 150
TDQDYLGKLS DTIDLVAQKD DAKRILENVN VVPVLTAHPT QIQRKTVLEL
160 170 180 190 200
TDKIHHLLRS YRDVKNGTIN QREWTEQLRA CIEILMQTDI IRGHKLKVSN
210 220 230 240 250
EITNVLAYYP KALIPAITKF TTRYKELAKE HNLTLDQATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAD TLELSATLQS QVIFEYYMKE LKKLYRAISL STSYMQPSAA
310 320 330 340 350
VEKLSKLSND DSPFRTDEPY RRAFYYIESR LVHTEKELLG IIDKNIFIKP
360 370 380 390 400
HDLENLDNIP VYNNPQEFKS DLETIKASLD EDHDQAVTHS FFTQILEAID
410 420 430 440 450
VFGFHLATID MRQDSSVNES CVAELLKSAG ICDNYSDLSE KEKVELLLSE
460 470 480 490 500
LENDPRNLHA NNKPKSELLQ KELKIYKTAR QLKDRLGEDV IKQHIISHTE
510 520 530 540 550
SVSDMLEQAI MLKEYNLVDS EKARIQVVPL FETVEDLLNA REIITQYLSF
560 570 580 590 600
PIVKKWLVSQ NNYQEIMLGY SDSNKDGGYL ASCWNLYKAQ KDLTAIGEKL
610 620 630 640 650
GVKITYMHGR GGTVGRGGGP SYEAITAQPF KSINDRIRMT EQGEIIQNKY
660 670 680 690 700
GNKDTAYYNL EMLASAAIDR MVSKQAVSEE RITDFRSSMD KIVEESNKIY
710 720 730 740 750
RKLVFENPAF LDYFFQATPI KEISNLNIGS RPASRKKLTD FSGLRAIPWV
760 770 780 790 800
FSWSQSRIMF PGWYGVGSAF ANFINADPTH LKELQEMYKG WPFFHSLLSN
810 820 830 840 850
VDMFLSKSNM EIAREYASLC DDEETKKVFD IIYQEWKLTK KVILQIEDHD
860 870 880 890 900
DLLAEAPILK QSLDYRMPYF NILNYIQIEM IKRGREDEIQ GVYQSIIPIT
910
INGVASGLRN SG
Length:912
Mass (Da):104,353
Last modified:March 1, 2005 - v1
Checksum:iEE482B5472CFC8D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000033 Genomic DNA Translation: AAV42936.1
RefSeqiWP_011254335.1, NC_006814.3
YP_193967.1, NC_006814.3

Genome annotation databases

EnsemblBacteriaiAAV42936; AAV42936; LBA1092
GeneIDi3253079
KEGGilac:LBA1092
PATRICifig|272621.13.peg.1039

Similar proteinsi

Entry informationi

Entry nameiCAPP_LACAC
AccessioniPrimary (citable) accession number: Q5FK38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: March 1, 2005
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health