Q5FGG9 (COXZ_EHRRG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase assembly protein CtaG

Gene names

Name:	ctaG
Ordered Locus Names:	ERGA_CDS_08460

Organism

Ehrlichia ruminantium (strain Gardel) [Complete proteome] [HAMAP]

Taxonomic identifier

302409 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity. HAMAP MF_00155
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side Potential HAMAP MF_00155.
Sequence similarities	Belongs to the COX11/CtaG family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Ligand	Copper
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 177	177	Cytochrome c oxidase assembly protein CtaG HAMAP MF_00155		PRO_0000246136
Regions
	Topological domain	1 – 8	8	Cytoplasmic Potential
	Transmembrane	9 – 29	21	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	30 – 177	148	Periplasmic Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5FGG9 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: BD25A06411E5183F	FASTA	177	20,329
	10 20 30 40 50 60 MTQKAKNTIY LLILIILSML CLVYASVPLY SIFCKVTGYG GTVRTATVTQ SKLGKTTIKI 70 80 90 100 110 120 RFNADINKEL PWKFYPEIPY TTVKPGEQKL IFYRAENLTN EYVSGMAVYN VTPYKVGKYF 130 140 150 160 170 NKVACFCFTK QTLSPYQKTI MPVSFFIDPN IETDPETSDV KLITLSYTFF KYKETTK

References

[1]

"Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity." Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D. J. Bacteriol. 188:2533-2542(2006) [PubMed: 16547041] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Gardel.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR925677 Genomic DNA. Translation: CAI28298.1.
RefSeq	YP_196772.1. NC_006831.1.
3D structure databases
ProteinModelPortal	Q5FGG9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5FGG9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3268454.
GenomeReviews	Gene locus ERGA_CDS_08460 in contig CR925677_GR.
KEGG	erg:ERGA_CDS_08460.
PATRIC	20579512. VBIEhrRum72196_0903.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3175.
HOGENOM	HBG525908.
OMA	KLIFYRA.
ProtClustDB	PRK05089.
Enzyme and pathway databases
BioCyc	ERUM302409:ERGA_CDS_08460-MONOMER.
Family and domain databases
HAMAP	MF_00155. CtaG. [Tree]
InterPro	IPR023471. CtaG/Cox11_dom. IPR007533. Cyt_c_oxidase_assmbl_CtaG. [Graphical view]
Gene3D	G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.
KO	K02258.
PANTHER	PTHR21320. CtaG_Cox11. 1 hit.
Pfam	PF04442. CtaG_Cox11. 1 hit. [Graphical view]
PIRSF	PIRSF005413. COX11. 1 hit.
SUPFAM	SSF110111. CtaG_Cox11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COXZ_EHRRG

Accession

Primary (citable) accession number: Q5FGG9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	March 1, 2005
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program