SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5FG57

- SYH_EHRRG

UniProt

Q5FG57 - SYH_EHRRG

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Histidine--tRNA ligase

Gene
hisS, ERGA_CDS_07280
Organism
Ehrlichia ruminantium (strain Gardel)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. histidine-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. histidyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciERUM302409:GHVW-761-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine--tRNA ligase (EC:6.1.1.21)
Alternative name(s):
Histidyl-tRNA synthetase
Short name:
HisRS
Gene namesi
Name:hisS
Ordered Locus Names:ERGA_CDS_07280
OrganismiEhrlichia ruminantium (strain Gardel)
Taxonomic identifieri302409 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
ProteomesiUP000000533: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 414414Histidine--tRNA ligaseUniRule annotationPRO_0000136157Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi302409.ERGA_CDS_07280.

Structurei

3D structure databases

ProteinModelPortaliQ5FG57.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0124.
HOGENOMiHOG000018072.
KOiK01892.
OMAiCGGGNFK.
OrthoDBiEOG6BPDH4.

Family and domain databases

Gene3Di3.40.50.800. 1 hit.
HAMAPiMF_00127. His_tRNA_synth.
InterProiIPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
[Graphical view]
PANTHERiPTHR11476. PTHR11476. 1 hit.
PfamiPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
PIRSFiPIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMiSSF52954. SSF52954. 1 hit.
TIGRFAMsiTIGR00442. hisS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FG57-1 [UniParc]FASTAAdd to Basket

« Hide

MQHNKLREVR GTKDLLDDEL YRFQYIQHLA QTIASRYGFI PVDTPIIEFT    50
EVFTKLGNTS DIVTKEMYNF KDKAGEDITL RPEFTSAIVR LLISKNLTIP 100
VKLFSSGPVF RYERPQKCRQ RQFHQINFEF FGSDSPIADV EMISLCYNIL 150
SELKLSDRIK LEINFLGDQE TINSYKIHLV EYLNKYQKDL SEDSQRRLVV 200
NPLRILDSKS PEDCKILLNA PSISDFYTQN SQNFFKEVLD GLDNLSINYV 250
INHNIVRGLD YYCKTVFEFT TSELGSQNSV IAGGRYDGLV KSMGGHSTPA 300
IGFAAGVERL SALIDYEHKK PKRIVLIPIG DDATSYAIKL AYELRCKGIH 350
VCWNNYRGTS LKNELRKAND TDIVLIFGDE ELQSNTVKVK DMKTGDQQNV 400
AVCDLLDNLL HRIV 414
Length:414
Mass (Da):47,382
Last modified:March 1, 2005 - v1
Checksum:i6907FECEB2E473FF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR925677 Genomic DNA. Translation: CAI28180.1.
RefSeqiWP_011255803.1. NC_006831.1.
YP_196654.1. NC_006831.1.

Genome annotation databases

EnsemblBacteriaiCAI28180; CAI28180; ERGA_CDS_07280.
GeneIDi3268584.
KEGGierg:ERGA_CDS_07280.
PATRICi20579250. VBIEhrRum72196_0774.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR925677 Genomic DNA. Translation: CAI28180.1 .
RefSeqi WP_011255803.1. NC_006831.1.
YP_196654.1. NC_006831.1.

3D structure databases

ProteinModelPortali Q5FG57.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 302409.ERGA_CDS_07280.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI28180 ; CAI28180 ; ERGA_CDS_07280 .
GeneIDi 3268584.
KEGGi erg:ERGA_CDS_07280.
PATRICi 20579250. VBIEhrRum72196_0774.

Phylogenomic databases

eggNOGi COG0124.
HOGENOMi HOG000018072.
KOi K01892.
OMAi CGGGNFK.
OrthoDBi EOG6BPDH4.

Enzyme and pathway databases

BioCyci ERUM302409:GHVW-761-MONOMER.

Family and domain databases

Gene3Di 3.40.50.800. 1 hit.
HAMAPi MF_00127. His_tRNA_synth.
InterProi IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
[Graphical view ]
PANTHERi PTHR11476. PTHR11476. 1 hit.
Pfami PF03129. HGTP_anticodon. 1 hit.
[Graphical view ]
PIRSFi PIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMi SSF52954. SSF52954. 1 hit.
TIGRFAMsi TIGR00442. hisS. 1 hit.
PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity."
    Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D.
    J. Bacteriol. 188:2533-2542(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Gardel.

Entry informationi

Entry nameiSYH_EHRRG
AccessioniPrimary (citable) accession number: Q5FG57
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: March 1, 2005
Last modified: September 3, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi