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Q5FE59 (Q5FE59_EHRRW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Dihydrodipicolinate synthase EMBL CAI26765.1
Gene names
Name:dapA EMBL CAI26765.1
Ordered Locus Names:ERWE_CDS_02710
OrganismEhrlichia ruminantium (strain Welgevonden) [Complete proteome] [HAMAP]
Taxonomic identifier254945 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263

Subcellular location

Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Diaminopimelate biosynthesis SAAS SAAS005263
Lysine biosynthesis SAAS SAAS005263
   Cellular componentCytoplasm SAAS SAAS005263
   LigandSchiff base SAAS SAAS005263
   Molecular functionLyase SAAS SAAS005263
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdiaminopimelate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondihydrodipicolinate synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q5FE59 [UniParc].

Last modified March 1, 2005. Version 1.
Checksum: 887D49B9A8B3E08D

FASTA30533,624
        10         20         30         40         50         60 
MIKNIEVLQM NSEKFKGVFT ALVTPFKNDF SVDQDAFTQL IEYQISNNVH GLVPCGSTGE 

        70         80         90        100        110        120 
STTLTFEEYC EIIKLCIKTT NNRVPIIAGS GSCSTQETIK RTLFVNSLNV DAALVVVPYY 

       130        140        150        160        170        180 
NRPTDEGIYQ HFKVVHDATN IPIIIYNIPK RTGVDVSDTL LARILSLPRV IGVKDATCDI 

       190        200        210        220        230        240 
SRPLNLKTLV QKDIVLFSGD DFTCLAFNSH GGSGCISAVS NVAPKICSDM QSAFFSNNIK 

       250        260        270        280        290        300 
EAIEISKTIL KLSQALFCES NPSPAKYALS LITEYISPIV RLPLVELTQE NKLKVENTLK 


ELGFI

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References

[1]"Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity."
Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D.
J. Bacteriol. 188:2533-2542(2006) [PubMed: 16547041] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Welgevonden [CIRAD].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR925678 Genomic DNA. Translation: CAI26765.1.
RefSeqYP_197147.1. NC_006832.1.

3D structure databases

ProteinModelPortalQ5FE59.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5FE59.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3261032.
GenomeReviewsGene locus ERWE_CDS_02710 in contig CR925678_GR.
KEGGerw:ERWE_CDS_02710.
PATRIC20580332. VBIEhrRum92411_0289.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0329.
HOGENOMHBG358848.
OMAHFKAVHD.
PhylomeDBQ5FE59.
ProtClustDBPRK03170.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR002220. Dihydrodipicolinate_synth-like.
IPR020625. Dihydrodipicolinate_synth_AS.
IPR020624. Dihydrodipicolinate_synth_CS.
IPR005263. Dihydrodipicolinate_synth_DapA.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01714.
PANTHERPTHR12128. DHDPS. 1 hit.
PfamPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFPIRSF001365. DHDPS. 1 hit.
PRINTSPR00146. DHPICSNTHASE.
TIGRFAMsTIGR00674. DapA. 1 hit.
PROSITEPS00665. DHDPS_1. 1 hit.
PS00666. DHDPS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5FE59_EHRRW
AccessionPrimary (citable) accession number: Q5FE59
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info