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Protein
Submitted name:

CASP1 nirs variant 1

Gene

CASP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CASP1 nirs variant 1Imported
Submitted name:
Caspase-1Imported
Gene namesi
Name:CASP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:1499. CASP1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000137752.

PTM / Processingi

Proteomic databases

MaxQBiQ5FBZ0.
PeptideAtlasiQ5FBZ0.
PRIDEiQ5FBZ0.

Expressioni

Gene expression databases

BgeeiENSG00000137752.
ExpressionAtlasiQ5FBZ0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000410076.

Structurei

3D structure databases

ProteinModelPortaliQ5FBZ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 91CARDInterPro annotationAdd BLAST91

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
GeneTreeiENSGT00760000118912.
HOVERGENiHBG006113.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR001315. CARD.
IPR011029. DEATH-like_dom.
[Graphical view]
PfamiPF00619. CARD. 1 hit.
[Graphical view]
SMARTiSM00114. CARD. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FBZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKVLKEKR KLFIRSMGEG TINGLLDELL QTRVLNKEEM EKVKRENATV
60 70 80 90 100
MDKTRALIDS VIPKGAQACQ ICITYICEED SYLAGTLGLS ADLSNNGQVK
110
PHTSCSHYLQ
Length:110
Mass (Da):12,259
Last modified:March 15, 2005 - v1
Checksum:iC032A1BAC7EDB668
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001153 Genomic DNA. No translation available.
KF455483 Genomic DNA. No translation available.
AB102878 mRNA. Translation: BAD89407.1.
UniGeneiHs.2490.

Genome annotation databases

EnsembliENST00000529871; ENSP00000431947; ENSG00000137752.
UCSCiuc058gyf.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001153 Genomic DNA. No translation available.
KF455483 Genomic DNA. No translation available.
AB102878 mRNA. Translation: BAD89407.1.
UniGeneiHs.2490.

3D structure databases

ProteinModelPortaliQ5FBZ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000410076.

Proteomic databases

MaxQBiQ5FBZ0.
PeptideAtlasiQ5FBZ0.
PRIDEiQ5FBZ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000529871; ENSP00000431947; ENSG00000137752.
UCSCiuc058gyf.1. human.

Organism-specific databases

HGNCiHGNC:1499. CASP1.
OpenTargetsiENSG00000137752.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
GeneTreeiENSGT00760000118912.
HOVERGENiHBG006113.

Miscellaneous databases

ChiTaRSiCASP1. human.

Gene expression databases

BgeeiENSG00000137752.
ExpressionAtlasiQ5FBZ0. baseline and differential.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR001315. CARD.
IPR011029. DEATH-like_dom.
[Graphical view]
PfamiPF00619. CARD. 1 hit.
[Graphical view]
SMARTiSM00114. CARD. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5FBZ0_HUMAN
AccessioniPrimary (citable) accession number: Q5FBZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: November 30, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.