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Protein
Submitted name:

IL7 nirs variant 1

Gene

IL7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
IL7 nirs variant 1Imported
Submitted name:
Interleukin-7Imported
Gene namesi
Name:IL7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:6023. IL7.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104432.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500770590026 – 115Sequence analysisAdd BLAST90

Proteomic databases

PeptideAtlasiQ5FBX5.
PRIDEiQ5FBX5.

Expressioni

Gene expression databases

BgeeiENSG00000104432.
ExpressionAtlasiQ5FBX5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000263851.

Structurei

3D structure databases

ProteinModelPortaliQ5FBX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IW6Q. Eukaryota.
ENOG41114MI. LUCA.
GeneTreeiENSGT00390000004451.
HOVERGENiHBG004609.

Family and domain databases

InterProiView protein in InterPro
IPR001181. IL-7.
IPR018049. IL-7/IL-9_CS.
IPR000226. IL-7/IL-9_fam.
PfamiView protein in Pfam
PF01415. IL7. 2 hits.
PRINTSiPR00435. INTERLEUKIN7.
SMARTiView protein in SMART
SM00127. IL7. 1 hit.
PROSITEiView protein in PROSITE
PS00255. INTERLEUKIN_7_9. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5FBX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFHVSFRYIF GLPPLILVLL PVASSDCDIE GKDGKQYESV LMVSIDQLLD
60 70 80 90 100
SMKEIGSNCL NNEFNFFKRH ICDANKEENK SLKEQKKLND LCFLKRLLQE
110
IKTCWNKILM GTKEH
Length:115
Mass (Da):13,370
Last modified:March 15, 2005 - v1
Checksum:iB64AFDB2BBFE3E7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC083837 Genomic DNA. No translation available.
AC100854 Genomic DNA. No translation available.
AB102893 mRNA. Translation: BAD89422.1.
RefSeqiNP_001186817.1. NM_001199888.1.
UniGeneiHs.591873.

Genome annotation databases

EnsembliENST00000379113; ENSP00000368408; ENSG00000104432.
GeneIDi3574.
UCSCiuc022awj.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC083837 Genomic DNA. No translation available.
AC100854 Genomic DNA. No translation available.
AB102893 mRNA. Translation: BAD89422.1.
RefSeqiNP_001186817.1. NM_001199888.1.
UniGeneiHs.591873.

3D structure databases

ProteinModelPortaliQ5FBX5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000263851.

Proteomic databases

PeptideAtlasiQ5FBX5.
PRIDEiQ5FBX5.

Protocols and materials databases

DNASUi3574.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379113; ENSP00000368408; ENSG00000104432.
GeneIDi3574.
UCSCiuc022awj.2. human.

Organism-specific databases

CTDi3574.
HGNCiHGNC:6023. IL7.
OpenTargetsiENSG00000104432.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IW6Q. Eukaryota.
ENOG41114MI. LUCA.
GeneTreeiENSGT00390000004451.
HOVERGENiHBG004609.

Miscellaneous databases

ChiTaRSiIL7. human.
GenomeRNAii3574.

Gene expression databases

BgeeiENSG00000104432.
ExpressionAtlasiQ5FBX5. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR001181. IL-7.
IPR018049. IL-7/IL-9_CS.
IPR000226. IL-7/IL-9_fam.
PfamiView protein in Pfam
PF01415. IL7. 2 hits.
PRINTSiPR00435. INTERLEUKIN7.
SMARTiView protein in SMART
SM00127. IL7. 1 hit.
PROSITEiView protein in PROSITE
PS00255. INTERLEUKIN_7_9. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5FBX5_HUMAN
AccessioniPrimary (citable) accession number: Q5FBX5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: February 15, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.