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Protein

Thiol:disulfide interchange protein

Gene

NGO_1438

Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.UniRule annotation

GO - Biological processi

Enzyme and pathway databases

BioCyciNGON242231:GI2G-1345-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thiol:disulfide interchange proteinUniRule annotation
Gene namesi
ORF Names:NGO_1438Imported
OrganismiNeisseria gonorrhoeae (strain ATCC 700825 / FA 1090)Imported
Taxonomic identifieri242231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000535 Componenti: Chromosome

Subcellular locationi

  • Periplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

PeriplasmUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19UniRule annotationAdd BLAST19
ChainiPRO_501000944120 – 261Thiol:disulfide interchange proteinUniRule annotationAdd BLAST242

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3GV1X-ray2.00A/B/C126-261[»]
ProteinModelPortaliQ5F6V7.
SMRiQ5F6V7.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5F6V7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini98 – 261ThioredoxinInterPro annotationAdd BLAST164

Sequence similaritiesi

Belongs to the thioredoxin family. DsbC subfamily.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation, SignalUniRule annotation

Phylogenomic databases

HOGENOMiHOG000222078.
KOiK03981.
OMAiQMIVYKA.

Family and domain databases

CDDicd03020. DsbA_DsbC_DsbG. 1 hit.
InterProiView protein in InterPro
IPR033954. DiS-bond_Isoase_DsbC/G.
IPR018950. DiS-bond_isomerase_DsbC/G_N.
IPR012336. Thioredoxin-like_fold.
IPR013766. Thioredoxin_domain.
PfamiView protein in Pfam
PF10411. DsbC_N. 1 hit.
PF13098. Thioredoxin_2. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.
SSF54423. SSF54423. 1 hit.
PROSITEiView protein in PROSITE
PS51352. THIOREDOXIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5F6V7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTKLIKILT PFTVLPLLAC GQTPVSNANA ESAVKAESAG KSVAASLKAR
60 70 80 90 100
LEKTYSAQDL KVLSVSETPV KGIYEVVVSG RQIIYTDAEG GYMFVGELIN
110 120 130 140 150
IDTRKNLTEE RAADLNKIDF ASLPLDKAIK EVRGNGKLKV AVFSDPDCPF
160 170 180 190 200
CKRLEHEFEK MTDVTVYSFM MPIAGLHPDA ARKAQILWCQ PDRAKAWTDW
210 220 230 240 250
MRKGKFPVGG SICDNPVAET TSLGEQFGFN GTPTLVFPNG RTQSGYSPMP
260
QLEEIIRKNQ Q
Length:261
Mass (Da):28,706
Last modified:March 15, 2005 - v1
Checksum:i5807D9B6C4F912D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004969 Genomic DNA. Translation: AAW90080.1.
RefSeqiWP_003689299.1. NC_002946.2.
YP_208492.1. NC_002946.2.

Genome annotation databases

EnsemblBacteriaiAAW90080; AAW90080; NGO_1438.
GeneIDi3281709.
KEGGingo:NGO_1438.
PATRICifig|242231.10.peg.1696.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ5F6V7_NEIG1
AccessioniPrimary (citable) accession number: Q5F6V7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: July 5, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported