Q5F6M8 (Q5F6M8_NEIG1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase 2 HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase 2 HAMAP MF_00020

Gene names

Name:	ackA2 HAMAP MF_00020
Ordered Locus Names:	NGO1521

Organism

Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)

Taxonomic identifier

242231 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020 RuleBase RU003835

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00020 SAAS SAAS000890 RuleBase RU003835 EMBL AAW90159.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5F6M8 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 3D6451212818C4D0	FASTA	399	42,970
	10 20 30 40 50 60 MSDQLILVLN CVSSSLKGAV IDRKSGSVVL SCLGERLTTP EAVITFNKDG NKRQVPLSGR 70 80 90 100 110 120 NCHAGAVGML LNELEKHGLH DRIKAIGRRI AHGGEKYHES VLIDQDVLDE LKACIPFAPL 130 140 150 160 170 180 HNPANISGIL AAQEHFPGLP NVGVMDTSFH QTMPERAYTY AVPRELRKKY AFRRYGFHGT 190 200 210 220 230 240 GMRYVAPEAA RILGKPLEDI RMIIAHLGNG ASITAVKNGK SVDTGMGFTP IEGLVMGTRC 250 260 270 280 290 300 GDTDPGVYSY PTFHAGMDVA QVDEMLNEKS GFPGISELPN DCRTLEIAAD EGREGARLAL 310 320 330 340 350 360 EVMTCRLAKY IASMAVACGS VDALVFTGGI GENSRNIRAK TVSYLDFLGL HIDTKANMEK 370 380 390 RYGNSGIISP TDSSPAVLVV PTNEELMIAC DTAELAGIL

References

[1]

"The complete genome sequence of Neisseria gonorrhoeae." Lewis L.A., Gillaspy A.F., McLaughlin R.E., Gipson M., Ducey T.F., Ownbey T., Hartman K., Nydick C., Carson M.B., Vaughn J., Thomson C., Song L., Lin S., Yuan X., Najar F., Zhan M., Ren Q., Zhu H. , Qi S., Kenton S.M., Lai H., White J.D., Clifton S., Roe B.A., Dyer D.W. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700825 / FA 1090.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004969 Genomic DNA. Translation: AAW90159.1.
RefSeq	YP_208571.1. NC_002946.2.
3D structure databases
ProteinModelPortal	Q5F6M8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5F6M8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBNEIT00000003992; EBNEIP00000003833; EBNEIG00000003992.
GeneID	3281543.
GenomeReviews	Gene locus NGO1521 in contig AE004969_GR.
KEGG	ngo:NGO1521.
NMPDR	fig|242231.4.peg.1571.
PATRIC	20336526. VBINeiGon24812_1811.
Phylogenomic databases
eggNOG	COG0282.
GeneTree	EBGT00050000020921.
HOGENOM	HBG285863.
OMA	AMEEGHE.
PhylomeDB	Q5F6M8.
ProtClustDB	PRK00180.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5F6M8_NEIG1

Accession

Primary (citable) accession number: Q5F6M8

Entry history

Integrated into UniProtKB/TrEMBL:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)