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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei145GTPUniRule annotation1
Binding sitei189GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciNGON242231:G1FZ9-1373-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:NGO_1528Imported
OrganismiNeisseria gonorrhoeae (strain ATCC 700825 / FA 1090)Imported
Taxonomic identifieri242231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000535 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ5F6M3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 207TubulinInterPro annotationAdd BLAST192
Domaini210 – 330Tubulin_CInterPro annotationAdd BLAST121

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5F6M3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFVYDVAES AVSPAVIKVI GLGGGGCNAI NNMVANNVRS VEFISANTDA
60 70 80 90 100
QSLAKNHAAK RIQLGTNLTR GLGAGANPDI GRAAAQEDRE AIEEAIRGAN
110 120 130 140 150
MLFITTGMGG GTGTGSAPVV AEIAKSLGIL TVAVVTRPFS YEGKRVHVAQ
160 170 180 190 200
AGLEQLKEYV DSLIIIPNDK LMTALGEDVT MREAFRAADN VLRDAVAGIS
210 220 230 240 250
EVVTCPSEII NLDFADVKTV MSNRGIAMMG SGYAQGIDRA RMATDQAISS
260 270 280 290 300
PLLDDVTLDG ARGVLVNITT APGCLKMSEL SEVMKIVNQS AHPDLECKFG
310 320 330 340 350
AAEDETMSED AIRITIIATG LKEKGAVDPT PAREVEAVAP SKQEQSHNVE
360 370 380 390
GMIRTNRGIR TMNLTAADFD NQSVLDDFEI PAILRRQHNS DK
Length:392
Mass (Da):41,511
Last modified:March 15, 2005 - v1
Checksum:iFF64B713FDD69DE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004969 Genomic DNA Translation: AAW90164.1
RefSeqiWP_003689432.1, NC_002946.2
YP_208576.1, NC_002946.2

Genome annotation databases

EnsemblBacteriaiAAW90164; AAW90164; NGO_1528
GeneIDi3281491
KEGGingo:NGO1528
PATRICifig|242231.10.peg.1824

Similar proteinsi

Entry informationi

Entry nameiQ5F6M3_NEIG1
AccessioniPrimary (citable) accession number: Q5F6M3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: March 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health