Q5F6H4 (MAFA2_NEIG1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adhesin MafA 2/3

Gene names

Name:	mafA2
Ordered Locus Names:	NGO1393
AND
Name:	mafA3
Ordered Locus Names:	NGO1584

Organism

Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) [Reference proteome] [HAMAP]

Taxonomic identifier

242231 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › Neisseria gonorrhoeae

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell outer membrane; Lipid-anchor Potential.
Sequence similarities	Belongs to the MafA family.

Ontologies

Keywords
Biological process	Cell adhesion Virulence
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: UniProtKB-KW pathogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 14	14	Potential
	Chain	15 – 313	299	Adhesin MafA 2/3		PRO_0000344484
Amino acid modifications
	Lipidation	15	1	N-palmitoyl cysteine Potential
	Lipidation	15	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5F6H4 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: E94135BC6B476162	FASTA	313	33,926
	10 20 30 40 50 60 MKTLLLLIPL VLTACGTLTG IPAHGGGKRF AVEQELVAAS SRAAVKEMDL SALKGRKAAL 70 80 90 100 110 120 YVSVMGDQGS GNISGGRYSI DALIRGGYHN NPDSATRYSY PAYDTTATTK SDALSGVTTS 130 140 150 160 170 180 TSLLNAPAAA LTKNNGRKGE RSAGLSVNGT GDYRNETLLA NPRDVSFLTN LIQTVFYLRG 190 200 210 220 230 240 IEVVPPEYAD TDVFVTVDVF GTVRSRTELH LYNAETLKAQ TKLEYFAVDR DSRKLLIAPK 250 260 270 280 290 300 TAAYESQYQE QYALWMGPYS VGKTVKASDR LMVDFSDITP YGDTTAQNRP DFKQNNGKNP 310 DVGNEVIRRR KGG

References

[1]

"The complete genome sequence of Neisseria gonorrhoeae." Lewis L.A., Gillaspy A.F., McLaughlin R.E., Gipson M., Ducey T.F., Ownbey T., Hartman K., Nydick C., Carson M.B., Vaughn J., Thomson C., Song L., Lin S., Yuan X., Najar F., Zhan M., Ren Q., Zhu H. , Qi S., Kenton S.M., Lai H., White J.D., Clifton S., Roe B.A., Dyer D.W. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700825 / FA 1090.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004969 Genomic DNA. Translation: AAW90041.1. AE004969 Genomic DNA. Translation: AAW90213.1.
RefSeq	YP_208453.1. NC_002946.2. YP_208625.1. NC_002946.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	242231.NGO1584.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAW90041; AAW90041; NGO1393. AAW90213; AAW90213; NGO1584.
GeneID	3281326. 3281439.
KEGG	ngo:NGO1393. ngo:NGO1584.
PATRIC	20336177. VBINeiGon24812_1637.
Phylogenomic databases
eggNOG	NOG76105.
HOGENOM	HOG000071263.
OMA	ATRYSYP.
ProtClustDB	CLSK877525.
Enzyme and pathway databases
BioCyc	NGON242231:GI2G-1269-MONOMER. NGON242231:GI2G-1441-MONOMER.
Family and domain databases
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MAFA2_NEIG1

Accession

Primary (citable) accession number: Q5F6H4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	March 15, 2005
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program