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Q5F694 (G6PI2_NEIG1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase 2

Short name=GPI 2
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 2
Short name=PGI 2
Phosphohexose isomerase 2
Short name=PHI 2
Gene names
Name:pgi2
Ordered Locus Names:NGO1668
OrganismNeisseria gonorrhoeae (strain ATCC 700825 / FA 1090) [Reference proteome] [HAMAP]
Taxonomic identifier242231 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length547 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 547547Glucose-6-phosphate isomerase 2 HAMAP-Rule MF_00473
PRO_0000180690

Sites

Active site3511Proton donor By similarity
Active site3821 By similarity
Active site5081 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5F694 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: FAD6BFEE1FD7D6F3

FASTA54760,317
        10         20         30         40         50         60 
MDAFTRAWYA LERHYQDTCH ILLRDRFAAE PDRFERMHER LDGMLFDYSK NRFGEDTLQL 

        70         80         90        100        110        120 
LCRLAETADL EGKMRALRTG AKVNGSEGRA ALHTALRLPD GADAVYADGR DVLPEIRREL 

       130        140        150        160        170        180 
NRALKFAHSL DDGLYQGITG KRIADFVHIG IGGSDLGPAM CVQALEPFRR QISVHFVSNA 

       190        200        210        220        230        240 
DPACLDEVLC RLNPETTMFC VASKSFKTPE TLLNAEAVKA WYRGAGFSES ETAHHFCAVS 

       250        260        270        280        290        300 
ADTEAAQSFG IAAERVFAMY DWVGGRYSVW SPVGLPVMVA VGGARFRELL AGAHAMDSHF 

       310        320        330        340        350        360 
FHTPPRRNIP VLMALIAVWY NNFQHADGQT AVPYSHNLRL LPAWLNQLDM ESLGKSRASD 

       370        380        390        400        410        420 
GSPAACKTGG IVFGGEGVNC QHAYFQLLHQ GTRLIPCDFI VPMTAQGAED GRSRFTVANA 

       430        440        450        460        470        480 
FAQAEALMKG KTLDEARAEL ADLPEAERER LAPHKEFPGN RPSNSILLDR LTPCNLGMLM 

       490        500        510        520        530        540 
AAYEHKTFVQ GAIWNVNPFD QWGVEYGKQL AKTIIGELEG GTSVHDASTE GLMAFYRECR 


LKGGGAA 

« Hide

References

[1]"The complete genome sequence of Neisseria gonorrhoeae."
Lewis L.A., Gillaspy A.F., McLaughlin R.E., Gipson M., Ducey T.F., Ownbey T., Hartman K., Nydick C., Carson M.B., Vaughn J., Thomson C., Song L., Lin S., Yuan X., Najar F., Zhan M., Ren Q., Zhu H. expand/collapse author list , Qi S., Kenton S.M., Lai H., White J.D., Clifton S., Roe B.A., Dyer D.W.
Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700825 / FA 1090.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004969 Genomic DNA. Translation: AAW90293.1.
RefSeqYP_208705.1. NC_002946.2.

3D structure databases

ProteinModelPortalQ5F694.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING242231.NGO1668.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW90293; AAW90293; NGO1668.
GeneID3281318.
KEGGngo:NGO1668.
PATRIC20336886. VBINeiGon24812_1988.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMASPAACKT.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycNGON242231:GI2G-1562-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI2_NEIG1
AccessionPrimary (citable) accession number: Q5F694
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 15, 2005
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways