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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 18FADUniRule annotation6
Nucleotide bindingi273 – 287NADUniRule annotationAdd BLAST15

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein, NAD

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:NGO1788
OrganismiNeisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Taxonomic identifieri242231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000535 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001171391 – 628tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGAdd BLAST628

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ5F5Y0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000201059.
KOiK03495.
OMAiFRPGYAI.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5F5Y0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYPKTYDVI VVGGGHAGTE AALAAARMGA QTLLLTHNIE TLGQMSCNPS
60 70 80 90 100
IGGIGKGHLV RELDALGGAM ALATDKSGIQ FRRLNASKGA AVRATRAQAD
110 120 130 140 150
RILYKASIRE MLENQENLDL FQQAVEDVTL EGERISGVIT AMGVEFKARA
160 170 180 190 200
VVLTAGTFLS GKIHIGLENY EGGRAGDPAA KSLGGRLREL KLPQGRLKTG
210 220 230 240 250
TPPRIDGRTI DFSQLTEQPG DTPVPVMSVR GNAEMHPRQV SCWITHTNTQ
260 270 280 290 300
THDIIRSGFD RSPMFTGKIE GVGPRYCPSI EDKINRFADK DSHQIFLEPE
310 320 330 340 350
GLTTHEYYPN GISTSLPFDI QIALVRSMKG LENAHILRPG YAIEYDYFDP
360 370 380 390 400
RNLKASLETK TIEGLFFAGQ INGTTGYEEA AAQGLLAGAN AVQYVRGQDP
410 420 430 440 450
LLLRREQAYL GVLVDDLITK GLNEPYRMFT SRAEYRLQLR EDNADMRLTE
460 470 480 490 500
DGYKIGLVGE AQWRMFNEKR EAVEREIQRL KTTWYTPQKL AEDEQIRVFG
510 520 530 540 550
QKLSREANLH DLLRRPNLDY AALMTLEGAM PSENLSAEVI EQVEIQVKYQ
560 570 580 590 600
GYIDRQNEEI DSRRDIETLK LPDGIDYGRV KGLSAEVQQK LNQHKPETVG
610 620
QASRISGVTP AAVALLMVHL KRGFKDAK
Length:628
Mass (Da):69,624
Last modified:March 15, 2005 - v1
Checksum:i71AE232546B197F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004969 Genomic DNA. Translation: AAW90407.1.
RefSeqiWP_010951347.1. NC_002946.2.
YP_208819.1. NC_002946.2.

Genome annotation databases

EnsemblBacteriaiAAW90407; AAW90407; NGO_1788.
GeneIDi3282494.
KEGGingo:NGO_1788.
PATRICi20337220. VBINeiGon24812_2146.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004969 Genomic DNA. Translation: AAW90407.1.
RefSeqiWP_010951347.1. NC_002946.2.
YP_208819.1. NC_002946.2.

3D structure databases

ProteinModelPortaliQ5F5Y0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW90407; AAW90407; NGO_1788.
GeneIDi3282494.
KEGGingo:NGO_1788.
PATRICi20337220. VBINeiGon24812_2146.

Phylogenomic databases

HOGENOMiHOG000201059.
KOiK03495.
OMAiFRPGYAI.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMNMG_NEIG1
AccessioniPrimary (citable) accession number: Q5F5Y0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 15, 2005
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.