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Q5F4T5

- Q5F4T5_9CALI

UniProt

Q5F4T5 - Q5F4T5_9CALI

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Protein
Submitted name: Capsid protein
Gene
N/A
Organism
Norwalk virus
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei299 – 2991GalactoseImported
Binding sitei381 – 3811Fucose
Binding sitei382 – 3821N-acetyl-D-glucosamineImported
Binding sitei385 – 3851FucoseImported
Binding sitei449 – 4491N-acetyl-D-glucosamine; via carbonyl oxygenImported

Names & Taxonomyi

Protein namesi
Submitted name:
Capsid proteinImported
OrganismiNorwalk virusImported
Taxonomic identifieri11983 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeNorovirus

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3ONUX-ray1.40A/B225-538[»]
3ONYX-ray1.85A/B/C225-538[»]
3PA1X-ray1.48A/B224-538[»]
3PA2X-ray1.48A/B224-538[»]
3Q38X-ray1.28A/B224-538[»]
3Q39X-ray1.25A/B224-538[»]
3Q3AX-ray1.40A/B224-538[»]
3Q6QX-ray1.43A/B224-538[»]
3Q6RX-ray1.40A/B224-538[»]
3RY8X-ray1.40A/B225-538[»]
3V7AX-ray3.30A/B224-538[»]
ProteinModelPortaliQ5F4T5.

Miscellaneous databases

EvolutionaryTraceiQ5F4T5.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni355 – 3562Fucose bindingImported
Regioni400 – 4012N-acetyl-D-glucosamine binding
Regioni451 – 4522Fucose bindingImported

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR004005. Calicivirus_coat.
IPR013643. Calicivirus_coat_C.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00915. Calici_coat. 1 hit.
PF08435. Calici_coat_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5F4T5-1 [UniParc]FASTAAdd to Basket

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MKMASNDAAP SNDGAAGLVP ESNNEVMALE PVAGASLAAP VTGQTNIIDP    50
WIRMNFVQAP NGEFTVSPRN SPGEVLLNLE LGPELNPYLA HLSRMYNGYA 100
GGMEVQIMLA GNAFTAGKLI FAAVPPHFPI ENLSPPQITM FPHVIIDVRT 150
LEPVLLPMPD IRNSFFHFIQ RDEPKMRLVA MLYTPLRSNG SGDDVFTVSC 200
RVLTRPTPDF DFTYLVPPTV ESKSKPFTLP ILTLGELTNS RFPLPIDVLY 250
TNPNESAIVQ CQNGRCTLDG ELQGTTQLLP TGICAFRGKV TQQVQDEHRG 300
THWNMTVTNL NGTPFDPTED VPAPLGTPDF SGQIYGVISQ RNTNTVPGEG 350
NLPANRAHEA VIATYSPKFT PKLGNIQFST WETQDVSSGQ PTKFTPVGLA 400
SVDANSHFDQ WTLPSYSGAL TLNMNLAPSV APVFPGECLL FFRSFIPLKG 450
GYGNPAIDCL MPQEWVQHLY QESAPSLSDV ALVRYVNPET GRTLFEAKLH 500
RNGFLTVARN SAGPVVAPTN GYFRFDSWVN QFYTLAPMGN GSGRRRMQ 548
Length:548
Mass (Da):59,900
Last modified:March 15, 2005 - v1
Checksum:iFDB134B87D09A39B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF504671 Genomic RNA. Translation: AAT12445.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF504671 Genomic RNA. Translation: AAT12445.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3ONU X-ray 1.40 A/B 225-538 [» ]
3ONY X-ray 1.85 A/B/C 225-538 [» ]
3PA1 X-ray 1.48 A/B 224-538 [» ]
3PA2 X-ray 1.48 A/B 224-538 [» ]
3Q38 X-ray 1.28 A/B 224-538 [» ]
3Q39 X-ray 1.25 A/B 224-538 [» ]
3Q3A X-ray 1.40 A/B 224-538 [» ]
3Q6Q X-ray 1.43 A/B 224-538 [» ]
3Q6R X-ray 1.40 A/B 224-538 [» ]
3RY8 X-ray 1.40 A/B 225-538 [» ]
3V7A X-ray 3.30 A/B 224-538 [» ]
ProteinModelPortali Q5F4T5.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei Q5F4T5.

Family and domain databases

Gene3Di 2.60.120.20. 1 hit.
InterProi IPR004005. Calicivirus_coat.
IPR013643. Calicivirus_coat_C.
IPR029053. Viral_coat.
[Graphical view ]
Pfami PF00915. Calici_coat. 1 hit.
PF08435. Calici_coat_C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Detection of norovirus and sapovirus infection among children with gastroenteritis in Ho Chi Minh City, Vietnam."
    Hansman G.S., Doan L.T., Kguyen T.A., Okitsu S., Katayama K., Ogawa S., Natori K., Takeda N., Kato Y., Nishio O., Noda M., Ushijima H.
    Arch. Virol. 149:1673-1688(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Vietnam 026Imported.
  2. "Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability."
    Hansman G.S., Biertumpfel C., Georgiev I., McLellan J.S., Chen L., Zhou T., Katayama K., Kwong P.D.
    J. Virol. 85:6687-6701(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS) OF 224-538 IN COMPLEX WITH FUCOSE; GALACTOSE AND N-ACETYL-D-GLUCOSAMINE.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS) OF 225-538.
  4. "Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle."
    Hansman G.S., Taylor D.W., McLellan J.S., Smith T.J., Georgiev I., Tame J.R., Park S.Y., Yamazaki M., Gondaira F., Miki M., Katayama K., Murata K., Kwong P.D.
    J. Virol. 86:3635-3646(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.30 ANGSTROMS) OF 224-538.

Entry informationi

Entry nameiQ5F4T5_9CALI
AccessioniPrimary (citable) accession number: Q5F4T5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: September 3, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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