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Q5F4T5

- Q5F4T5_9CALI

UniProt

Q5F4T5 - Q5F4T5_9CALI

Protein
Submitted name:

Capsid protein

Gene
N/A
Organism
Norwalk virus
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (15 Mar 2005)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei299 – 2991GalactoseImported
    Binding sitei381 – 3811Fucose
    Binding sitei382 – 3821N-acetyl-D-glucosamineImported
    Binding sitei385 – 3851FucoseImported
    Binding sitei449 – 4491N-acetyl-D-glucosamine; via carbonyl oxygenImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Capsid proteinImported
    OrganismiNorwalk virusImported
    Taxonomic identifieri11983 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeNorovirus

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ONUX-ray1.40A/B225-538[»]
    3ONYX-ray1.85A/B/C225-538[»]
    3PA1X-ray1.48A/B224-538[»]
    3PA2X-ray1.48A/B224-538[»]
    3Q38X-ray1.28A/B224-538[»]
    3Q39X-ray1.25A/B224-538[»]
    3Q3AX-ray1.40A/B224-538[»]
    3Q6QX-ray1.43A/B224-538[»]
    3Q6RX-ray1.40A/B224-538[»]
    3RY8X-ray1.40A/B225-538[»]
    3V7AX-ray3.30A/B224-538[»]
    ProteinModelPortaliQ5F4T5.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ5F4T5.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni355 – 3562Fucose bindingImported
    Regioni400 – 4012N-acetyl-D-glucosamine binding
    Regioni451 – 4522Fucose bindingImported

    Family and domain databases

    Gene3Di2.60.120.20. 1 hit.
    InterProiIPR004005. Calicivirus_coat.
    IPR013643. Calicivirus_coat_C.
    IPR029053. Viral_coat.
    [Graphical view]
    PfamiPF00915. Calici_coat. 1 hit.
    PF08435. Calici_coat_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5F4T5-1 [UniParc]FASTAAdd to Basket

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    MKMASNDAAP SNDGAAGLVP ESNNEVMALE PVAGASLAAP VTGQTNIIDP    50
    WIRMNFVQAP NGEFTVSPRN SPGEVLLNLE LGPELNPYLA HLSRMYNGYA 100
    GGMEVQIMLA GNAFTAGKLI FAAVPPHFPI ENLSPPQITM FPHVIIDVRT 150
    LEPVLLPMPD IRNSFFHFIQ RDEPKMRLVA MLYTPLRSNG SGDDVFTVSC 200
    RVLTRPTPDF DFTYLVPPTV ESKSKPFTLP ILTLGELTNS RFPLPIDVLY 250
    TNPNESAIVQ CQNGRCTLDG ELQGTTQLLP TGICAFRGKV TQQVQDEHRG 300
    THWNMTVTNL NGTPFDPTED VPAPLGTPDF SGQIYGVISQ RNTNTVPGEG 350
    NLPANRAHEA VIATYSPKFT PKLGNIQFST WETQDVSSGQ PTKFTPVGLA 400
    SVDANSHFDQ WTLPSYSGAL TLNMNLAPSV APVFPGECLL FFRSFIPLKG 450
    GYGNPAIDCL MPQEWVQHLY QESAPSLSDV ALVRYVNPET GRTLFEAKLH 500
    RNGFLTVARN SAGPVVAPTN GYFRFDSWVN QFYTLAPMGN GSGRRRMQ 548
    Length:548
    Mass (Da):59,900
    Last modified:March 15, 2005 - v1
    Checksum:iFDB134B87D09A39B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF504671 Genomic RNA. Translation: AAT12445.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF504671 Genomic RNA. Translation: AAT12445.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ONU X-ray 1.40 A/B 225-538 [» ]
    3ONY X-ray 1.85 A/B/C 225-538 [» ]
    3PA1 X-ray 1.48 A/B 224-538 [» ]
    3PA2 X-ray 1.48 A/B 224-538 [» ]
    3Q38 X-ray 1.28 A/B 224-538 [» ]
    3Q39 X-ray 1.25 A/B 224-538 [» ]
    3Q3A X-ray 1.40 A/B 224-538 [» ]
    3Q6Q X-ray 1.43 A/B 224-538 [» ]
    3Q6R X-ray 1.40 A/B 224-538 [» ]
    3RY8 X-ray 1.40 A/B 225-538 [» ]
    3V7A X-ray 3.30 A/B 224-538 [» ]
    ProteinModelPortali Q5F4T5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q5F4T5.

    Family and domain databases

    Gene3Di 2.60.120.20. 1 hit.
    InterProi IPR004005. Calicivirus_coat.
    IPR013643. Calicivirus_coat_C.
    IPR029053. Viral_coat.
    [Graphical view ]
    Pfami PF00915. Calici_coat. 1 hit.
    PF08435. Calici_coat_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Detection of norovirus and sapovirus infection among children with gastroenteritis in Ho Chi Minh City, Vietnam."
      Hansman G.S., Doan L.T., Kguyen T.A., Okitsu S., Katayama K., Ogawa S., Natori K., Takeda N., Kato Y., Nishio O., Noda M., Ushijima H.
      Arch. Virol. 149:1673-1688(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Vietnam 026Imported.
    2. "Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability."
      Hansman G.S., Biertumpfel C., Georgiev I., McLellan J.S., Chen L., Zhou T., Katayama K., Kwong P.D.
      J. Virol. 85:6687-6701(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS) OF 224-538 IN COMPLEX WITH FUCOSE; GALACTOSE AND N-ACETYL-D-GLUCOSAMINE.
    3. Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS) OF 225-538.
    4. "Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle."
      Hansman G.S., Taylor D.W., McLellan J.S., Smith T.J., Georgiev I., Tame J.R., Park S.Y., Yamazaki M., Gondaira F., Miki M., Katayama K., Murata K., Kwong P.D.
      J. Virol. 86:3635-3646(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.30 ANGSTROMS) OF 224-538.

    Entry informationi

    Entry nameiQ5F4T5_9CALI
    AccessioniPrimary (citable) accession number: Q5F4T5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 15, 2005
    Last sequence update: March 15, 2005
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3