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Protein

Lipoma-preferred partner homolog

Gene

LPP

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a structural role at sites of cell adhesion in maintaining cell shape and motility. May be involved in signal transduction from cell adhesion sites to the nucleus (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Lipoma-preferred partner homolog
Gene namesi
Name:LPP
ORF Names:RCJMB04_2l20
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 9

Subcellular locationi

  • Nucleus By similarity
  • Cytoplasm By similarity
  • Cell junction By similarity

  • Note: Found in the nucleus, in the cytoplasm and at cell adhesion sites.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 604604Lipoma-preferred partner homologPRO_0000075835Add
BLAST

Proteomic databases

PaxDbiQ5F464.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000011857.

Structurei

3D structure databases

ProteinModelPortaliQ5F464.
SMRiQ5F464. Positions 413-525.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini406 – 46560LIM zinc-binding 1PROSITE-ProRule annotationAdd
BLAST
Domaini466 – 52661LIM zinc-binding 2PROSITE-ProRule annotationAdd
BLAST
Domaini527 – 59569LIM zinc-binding 3PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi42 – 381340Pro-richAdd
BLAST

Sequence similaritiesi

Belongs to the zyxin/ajuba family.Curated
Contains 3 LIM zinc-binding domains.PROSITE-ProRule annotation

Keywords - Domaini

LIM domain, Repeat

Phylogenomic databases

eggNOGiKOG1701. Eukaryota.
ENOG410Y3GP. LUCA.
GeneTreeiENSGT00760000119039.
HOGENOMiHOG000220910.
HOVERGENiHBG093602.
InParanoidiQ5F464.
KOiK16676.
OMAiRNDSDPA.
OrthoDBiEOG7992Q6.
PhylomeDBiQ5F464.
TreeFamiTF320310.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiIPR028771. LPP.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR24207:SF0. PTHR24207:SF0. 2 hits.
PfamiPF00412. LIM. 3 hits.
[Graphical view]
SMARTiSM00132. LIM. 3 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5F464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHPSWLPPK STNEPVGHVT ARMETTHAFG TPSISVSTQQ TPKKFAPVVA
60 70 80 90 100
PKPKYNPYKQ PGGDGDFLPP PPPPVDDLGN ITSQGAFPPP PPLDDVAFNV
110 120 130 140 150
QVNPGGKTLE ERRSSLDAEI DSLTSILADL ESSSPYKPRI QQGSGTSSSA
160 170 180 190 200
ATTPSVSTPV TGHKRMIIPN QPPLTATKKS TAKGPGQPAP IPVTPIGTLK
210 220 230 240 250
PQPVPASYTT ASTPSRPTFN VQVRTAQPSP HYQPPGPQPT HYGSLGPGQP
260 270 280 290 300
YAAPPARPPG AQQYGSPQPR GPDYGYAPPP ARPSEPSYGY APQQGRYQDP
310 320 330 340 350
YYGGYGGRNG SEAPYMPQST WKVEPAYPSS NTVGQAPPGM YQHPGPKKTY
360 370 380 390 400
ITDPVLAPQP LQQKSGYPSS GPTSSTPAFR PEDELEHLTK KMLYDMENPP
410 420 430 440 450
SDDYFGRCAR CGENVVGEGT GCTAMDQVFH VECFTCMMCN NKLRGQPFYA
460 470 480 490 500
VEKKAYCEPC YINTLEQCSV CAKPIMERIL RATGKAYHPH CFTCVMCHRS
510 520 530 540 550
LDGIPFTVDA GGNIHCIEDF HKKFAPRCSV CKEPIMPAPG QEETVRIVAL
560 570 580 590 600
DRDFHVQCYR CEDCGGLLSE GDNQGCYPLD GHILCKTCNS ARIQALTAKA

STDL
Length:604
Mass (Da):65,139
Last modified:March 15, 2005 - v1
Checksum:iE3DBF28A196F4C43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ851436 mRNA. Translation: CAH65070.1.
RefSeqiNP_001026738.1. NM_001031567.1.
XP_015146918.1. XM_015291432.1.
XP_015146919.1. XM_015291433.1.
XP_015146921.1. XM_015291435.1.
XP_015146922.1. XM_015291436.1.
XP_015146923.1. XM_015291437.1.
XP_015146924.1. XM_015291438.1.
XP_015146925.1. XM_015291439.1.
XP_015146926.1. XM_015291440.1.
UniGeneiGga.22742.

Genome annotation databases

EnsembliENSGALT00000011871; ENSGALP00000011857; ENSGALG00000007337.
GeneIDi429148.
KEGGigga:429148.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ851436 mRNA. Translation: CAH65070.1.
RefSeqiNP_001026738.1. NM_001031567.1.
XP_015146918.1. XM_015291432.1.
XP_015146919.1. XM_015291433.1.
XP_015146921.1. XM_015291435.1.
XP_015146922.1. XM_015291436.1.
XP_015146923.1. XM_015291437.1.
XP_015146924.1. XM_015291438.1.
XP_015146925.1. XM_015291439.1.
XP_015146926.1. XM_015291440.1.
UniGeneiGga.22742.

3D structure databases

ProteinModelPortaliQ5F464.
SMRiQ5F464. Positions 413-525.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000011857.

Proteomic databases

PaxDbiQ5F464.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000011871; ENSGALP00000011857; ENSGALG00000007337.
GeneIDi429148.
KEGGigga:429148.

Organism-specific databases

CTDi4026.

Phylogenomic databases

eggNOGiKOG1701. Eukaryota.
ENOG410Y3GP. LUCA.
GeneTreeiENSGT00760000119039.
HOGENOMiHOG000220910.
HOVERGENiHBG093602.
InParanoidiQ5F464.
KOiK16676.
OMAiRNDSDPA.
OrthoDBiEOG7992Q6.
PhylomeDBiQ5F464.
TreeFamiTF320310.

Miscellaneous databases

NextBioi20829961.
PROiQ5F464.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiIPR028771. LPP.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR24207:SF0. PTHR24207:SF0. 2 hits.
PfamiPF00412. LIM. 3 hits.
[Graphical view]
SMARTiSM00132. LIM. 3 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: CB.
    Tissue: Bursa of Fabricius.

Entry informationi

Entry nameiLPP_CHICK
AccessioniPrimary (citable) accession number: Q5F464
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: March 15, 2005
Last modified: March 16, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.