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Protein

Sister chromatid cohesion protein PDS5 homolog A

Gene

PDS5A

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May regulate sister chromatid cohesion during mitosis and couple it to DNA replication.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Names & Taxonomyi

Protein namesi
Recommended name:
Sister chromatid cohesion protein PDS5 homolog A
Gene namesi
Name:PDS5ABy similarity
ORF Names:RCJMB04_6f4
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

  • Nucleus By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13301330Sister chromatid cohesion protein PDS5 homolog APRO_0000296344Add
BLAST

Proteomic databases

PaxDbiQ5F3V3.

Interactioni

Subunit structurei

Interacts with the cohesin complex. Binds chromatin in a cohesin-dependent manner (By similarity).By similarity

Protein-protein interaction databases

STRINGi9031.ENSGALP00000023059.

Structurei

3D structure databases

ProteinModelPortaliQ5F3V3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati387 – 42337HEATSequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the PDS5 family.Curated
Contains 1 HEAT repeat.Sequence analysis

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG1525. Eukaryota.
ENOG410XQW7. LUCA.
HOGENOMiHOG000230672.
HOVERGENiHBG108241.
InParanoidiQ5F3V3.
KOiK11267.
PhylomeDBiQ5F3V3.

Family and domain databases

Gene3Di1.25.10.10. 7 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 4 hits.

Sequencei

Sequence statusi: Complete.

Q5F3V3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFPAAQPKP AADGKIIYYP PGVKETTDKI TNDEVVKRLK MVVKTFMDMD
60 70 80 90 100
QDSEDEKQQY LPLALHLASE FFLRNPNKDV RLLVACCLAD IFRIYAPEAP
110 120 130 140 150
YTSHDKLKDI FLFITRQLKG LEDTKSPQFN RYFYLLENLA WVKSYNICFE
160 170 180 190 200
LEDCNEIFIQ LFRTLFSVIN NSHNQKVQMH MLDLMSSIIM EGDGVTQELL
210 220 230 240 250
DSILINLIPA HKNLNKQAFD LAKVLLKRTV QTIEPCIANF FNQVLVLGKS
260 270 280 290 300
SVSDLSEHVF DLILELFAID PHLLLSVMPQ LEFKLKSNDG EERLAVVRLL
310 320 330 340 350
AKLFGSKDSD LATQNRPLWQ CFLGRFNDIH VPVRLESVKF ASHCLMNHPD
360 370 380 390 400
LAKDLTEYLK VRSHDPEEAI RHDVIVTIIT AGKRDLSLVN DQLLGFVRER
410 420 430 440 450
TLDKRWRVRK EAMMGLAQLY KKYCLHAEAG KDAAEKVSWI KDKLLHIYYQ
460 470 480 490 500
NSIDDKLLVE KIFAQYLVPH NLETEERMKC LYYLYASLDP NAVKALNEMW
510 520 530 540 550
KCQNMLRSHV RELLDLHKQP TSEANSAAMF GKLMTIAKNL PDPGKAQDFV
560 570 580 590 600
KKFNQVLGDD EKLRSQLELL ISPTCSCKQA DVCVREIARK LANPKQPTNP
610 620 630 640 650
FLEMVKFLLE RIAPVHIDSE AISALVKLMN KSIEGTADDE EEGVSPDTAI
660 670 680 690 700
RAGLELLKVL SFTHPTSFHS AETYESLLQC LRMEDDKVAE AAIQIFRNTG
710 720 730 740 750
HKIETDLPQI RSTLIPILHQ KAKRGTPHQA KQAVHCIHAI FSNKEVQLAQ
760 770 780 790 800
IFEPLSRSLN ADVPEQLITP LVSLGHISML APDQFASPMK SVVANFVVKD
810 820 830 840 850
LLMNDRSTGE KNGKLWSPDE EVSPEVLAKV QAIKLLVRWL LGMKNNQSKS
860 870 880 890 900
ANSTLRLLSA MLVSEGDLTE QKRISKSDMS RLRLAAGSAI MKLAQEPCYH
910 920 930 940 950
EIITPEQFQL CALVINDECY QVRQIFAQKL HKALVKLLLP LEYMAIFALC
960 970 980 990 1000
AKDPVKERRA HARQCLLKNI SIRREYIKQN PMANEKLLSL LPEYVVPYMI
1010 1020 1030 1040 1050
HLLAHDPDFT KPQDVDQLRD VKECLWFMLE VLMTKNENNS HAFMKKMAEN
1060 1070 1080 1090 1100
IKLTRDAQSP DEPKANEKLY TVCDVALCVI NSKSALCNAD SPKDPVLPTK
1110 1120 1130 1140 1150
FFTQPEKDFS NDRNYISEET RVLLLTGKPK PTGVLDTVNK PLSATGRRPY
1160 1170 1180 1190 1200
IRTTGSETGS NISVNSELSS SAGNRSREQS SDISETGVSE NDENPVRIIS
1210 1220 1230 1240 1250
VTPAKTEPVK NKEINSDQAT QGNSTERGKK RTATASGTEN IHQKAEENNA
1260 1270 1280 1290 1300
DETGPSLAAK TRRGRPPKPE PQGTTAKNEE TNKPPVRGRK RAAASQESPG
1310 1320 1330
SLEAGNAKAP KQQDTAKKPA AAQRQIDLQR
Length:1,330
Mass (Da):150,132
Last modified:July 24, 2007 - v2
Checksum:i0241C02AEF8C1AF4
GO

Sequence cautioni

The sequence CAH65181.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ851547 mRNA. Translation: CAH65181.1. Different initiation.
RefSeqiNP_001012598.1. NM_001012580.1.
UniGeneiGga.17541.

Genome annotation databases

GeneIDi422787.
KEGGigga:422787.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ851547 mRNA. Translation: CAH65181.1. Different initiation.
RefSeqiNP_001012598.1. NM_001012580.1.
UniGeneiGga.17541.

3D structure databases

ProteinModelPortaliQ5F3V3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000023059.

Proteomic databases

PaxDbiQ5F3V3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi422787.
KEGGigga:422787.

Organism-specific databases

CTDi23244.

Phylogenomic databases

eggNOGiKOG1525. Eukaryota.
ENOG410XQW7. LUCA.
HOGENOMiHOG000230672.
HOVERGENiHBG108241.
InParanoidiQ5F3V3.
KOiK11267.
PhylomeDBiQ5F3V3.

Miscellaneous databases

PROiQ5F3V3.

Family and domain databases

Gene3Di1.25.10.10. 7 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 4 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: CBImported.
    Tissue: Bursa of FabriciusImported.

Entry informationi

Entry nameiPDS5A_CHICK
AccessioniPrimary (citable) accession number: Q5F3V3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: June 8, 2016
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.