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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

RCJMB04_17g4

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
ORF Names:RCJMB04_17g4Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

PTM / Processingi

Proteomic databases

PaxDbiQ5F3G9.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000012720.

Structurei

3D structure databases

ProteinModelPortaliQ5F3G9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 126Lipoyl-bindingInterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

eggNOGiKOG0557. Eukaryota.
COG0508. LUCA.
HOGENOMiHOG000281566.
HOVERGENiHBG005063.
KOiK13997.
PhylomeDBiQ5F3G9.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5F3G9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASWWRSGG AGVLRLLRGG RPVLSAGLAV PARGGWRFLH GTQELLGTPA
60 70 80 90 100
IKVLMPALSP TMEEGNIVKW LKKEGEMVNA GDALCEIETD KAVVTMESSD
110 120 130 140 150
DGILAKILVE EGSKNVRLGS LIGLLVEEGQ DWKQVEIPAD ANDQSSLAPP
160 170 180 190 200
AAAVTSTPAG PSVSAPPKVE HQPGKLQFRL SPAARNIVET HGLDPSSVTP
210 220 230 240 250
SGPRGIFTKE DALKLLQGKQ KDKPSELKPV VSPATPQPTA VPSALPAAAV
260 270 280 290 300
PSAYPRPIVP PVSTPGQPAA PGTFTEIPAS NIRRVIAKRL TESKTTIPHA
310 320 330 340 350
YAAADCDIDA ILKLRSELAK DDIKVSVNDF IIKAAAVTLK QMPDVNATWD
360 370 380 390 400
GEGCRQLQSI DISIAVATDR GLITPIIKDV PAKGIQEIAA SAKALAKKAR
410 420 430 440 450
DGKLLPEEYQ GGSFSISNLG MFGINDFIAV INPPQACILA VGRARPELKI
460 470 480 490 500
VEDEEGNEKL KQHQLMTVTL SSDGRVVDDE LASKFLETFK ANIENPIRLA

LC
Length:502
Mass (Da):53,219
Last modified:March 15, 2005 - v1
Checksum:iB2AB7FA272AC9D5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ851681 mRNA. Translation: CAH65315.1.
RefSeqiNP_001026358.1. NM_001031187.1.
UniGeneiGga.20259.
Gga.44627.

Genome annotation databases

GeneIDi423154.
KEGGigga:423154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ851681 mRNA. Translation: CAH65315.1.
RefSeqiNP_001026358.1. NM_001031187.1.
UniGeneiGga.20259.
Gga.44627.

3D structure databases

ProteinModelPortaliQ5F3G9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000012720.

Proteomic databases

PaxDbiQ5F3G9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi423154.
KEGGigga:423154.

Organism-specific databases

CTDi8050.

Phylogenomic databases

eggNOGiKOG0557. Eukaryota.
COG0508. LUCA.
HOGENOMiHOG000281566.
HOVERGENiHBG005063.
KOiK13997.
PhylomeDBiQ5F3G9.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5F3G9_CHICK
AccessioniPrimary (citable) accession number: Q5F3G9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: October 5, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.