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Q5F2J0 (PTP1_ENCIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Polar tube protein 1
Alternative name(s):
Major polar tube protein
Short name=Major PTP
Gene names
Name:PTP1
OrganismEncephalitozoon intestinalis (Microsporidian parasite)
Taxonomic identifier58839 [NCBI]
Taxonomic lineageEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved with PTP2 and PTP3 in formation of a polar tube through which the infectious agent is passed on to the host cell By similarity.

Subcellular location

Spore polar tube By similarity.

Post-translational modification

Glycosylated. Ref.2

Miscellaneous

The host antibody response is directed against the post-translational carbohydrate modification.

Ontologies

Keywords
   Biological processSporulation
   DomainSignal
   PTMGlycoprotein
Gene Ontology (GO)
   Biological_processsporulation resulting in formation of a cellular spore

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentpolar tube

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 371349Polar tube protein 1
PRO_0000377522

Sequences

Sequence LengthMass (Da)Tools
Q5F2J0 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 1A9733EB8B5B6625

FASTA37137,520
        10         20         30         40         50         60 
MKGISKVLSA SIVLMKLKGV YSTTVLCGDS TQGLQGTTQP SYVLVPSAPE TIANCGYSPQ 

        70         80         90        100        110        120 
NMYVPSTPTT MPSTVPGTTG ESETPTSPTS SPTEDVGTCK IAVVKHCDAP GTSSTPCEPE 

       130        140        150        160        170        180 
QTLAPSQPVA ATIATPLVVA SVQTPQAAVT ILTPKAVSAQ PATIISPFNQ APGYYNSAIP 

       190        200        210        220        230        240 
GQILTGNVLS PSASSCQVVP GTTGSSTPQQ LPGAVSSGTI PCQIVQGTQS SGNTPGQQFL 

       250        260        270        280        290        300 
PGIVPVGSLQ PDQATSGTPT PSVSQSQSGQ QCCCTPPITN PVMPTPMGIS SNGYPSSTAY 

       310        320        330        340        350        360 
APTLGQLGPC IDTQKSTSSC EPKEKPVAQY GMEACAAPTP TAVLGNAEYL LSPGMYNSLN 

       370 
SPCNACCQQQ C 

« Hide

References

[1]"Microsporidian invasion apparatus: identification of a novel polar tube protein and evidence for clustering of ptp1 and ptp2 genes in three Encephalitozoon species."
Delbac F., Peuvel I., Metenier G., Peyretaillade E., Vivares C.P.
Infect. Immun. 69:1016-1024(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Carbohydrate moieties of microsporidian polar tube proteins are targeted by immunoglobulin G in immunocompetent individuals."
Peek R., Delbac F., Speijer D., Polonais V., Greve S., Wentink-Bonnema E., Ringrose J., van Gool T.
Infect. Immun. 73:7906-7913(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION AS AN ANTIGEN, GLYCOSYLATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AX007051 Genomic DNA. No translation available.
AJ880382 Genomic DNA. Translation: CAI54279.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry namePTP1_ENCIN
AccessionPrimary (citable) accession number: Q5F2J0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: March 15, 2005
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program