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Protein

Protein ABHD15

Gene

Abhd15

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei351 – 3511Charge relay systemBy similarity
Active sitei382 – 3821Charge relay systemBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Protein family/group databases

ESTHERimouse-ABH15. abh_upf0017.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ABHD15Curated (EC:3.1.1.-)
Alternative name(s):
Alpha/beta hydrolase domain-containing protein 15Curated
Short name:
Abhydrolase domain-containing protein 15Imported
Gene namesi
Name:Abhd15Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1914727. Abhd15.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 459431Protein ABHD15PRO_0000345396Add
BLAST

Proteomic databases

EPDiQ5F2F2.
MaxQBiQ5F2F2.
PaxDbiQ5F2F2.
PRIDEiQ5F2F2.

PTM databases

iPTMnetiQ5F2F2.
PhosphoSiteiQ5F2F2.

Expressioni

Gene expression databases

BgeeiQ5F2F2.
ExpressionAtlasiQ5F2F2. baseline and differential.
GenevisibleiQ5F2F2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091541.

Structurei

3D structure databases

ProteinModelPortaliQ5F2F2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1838. Eukaryota.
COG0429. LUCA.
GeneTreeiENSGT00530000062981.
HOGENOMiHOG000033769.
InParanoidiQ5F2F2.
KOiK13707.
OMAiETLFCHT.
OrthoDBiEOG7J70FM.
PhylomeDBiQ5F2F2.
TreeFamiTF332985.

Family and domain databases

Gene3Di3.40.50.1820. 2 hits.
InterProiIPR029058. AB_hydrolase.
IPR012020. ABHD4.
[Graphical view]
PIRSFiPIRSF005211. Ab_hydro_YheT. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5F2F2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPWAAALAL LLAALALLLL RPWKRAVGAR TSVRDHEEQE VASGGPADQF
60 70 80 90 100
SDRREALPGG CSLICKPSAL AQCLLRALRR SAALEPSPRS WLSGPHLQTF
110 120 130 140 150
CHFILPVGPG PELAREYLQL ADDGLVALDW VIGPCARGRR VTNPGSLPPV
160 170 180 190 200
LLVIPNAWGR LTRNVLGLCL LALERGYYPV IFHRRGHHGC PLVSPRLQPF
210 220 230 240 250
GDPSDLKEAV TYIRFRHPAA PLFAVSEGSG SALLLSYLGE CGSSSYVTGA
260 270 280 290 300
ACISPVLRCR EWFEAGLPWP YERGFLLHQK ISLSRYASAL EDTVDTGKLF
310 320 330 340 350
RSGSLREFEE TLFCHTKSCP ISWDTYWDLN DPLRDVDEAA VPVLCICSAD
360 370 380 390 400
DPVCGPPEHT LPAELFHSNP YFFLLLSHHG GHCGFLRPEP LPAWSHEVIL
410 420 430 440 450
ESFRALTEFF RMEERMKGLS RRRTSFLGGR RRWGGLQKRE VSPSSNLEEI

FNWKRSYTR
Length:459
Mass (Da):51,152
Last modified:March 15, 2005 - v1
Checksum:i30D897F050943B82
GO

Sequence cautioni

The sequence BAB31349.1 differs from that shown. Reason: Frameshift at position 385. Curated
The sequence BAC25102.1 differs from that shown. Reason: Frameshift at position 358. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti106 – 1061P → L in BAB31349 (PubMed:16141072).Curated
Sequence conflicti147 – 1471L → H in BAE20655 (PubMed:16141072).Curated
Sequence conflicti305 – 3051L → V in BAB31349 (PubMed:16141072).Curated
Sequence conflicti308 – 3081F → C in BAB31349 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018696 mRNA. Translation: BAB31349.1. Frameshift.
AK004929 mRNA. Translation: BAC25102.1. Frameshift.
AK042032 mRNA. Translation: BAC31138.1.
AK046590 mRNA. Translation: BAE20655.1.
AL591136 Genomic DNA. Translation: CAI51872.1.
CCDSiCCDS36234.1.
RefSeqiNP_080461.3. NM_026185.4.
UniGeneiMm.432526.
Mm.487555.

Genome annotation databases

EnsembliENSMUST00000094004; ENSMUSP00000091541; ENSMUSG00000000686.
GeneIDi67477.
KEGGimmu:67477.
UCSCiuc007kha.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018696 mRNA. Translation: BAB31349.1. Frameshift.
AK004929 mRNA. Translation: BAC25102.1. Frameshift.
AK042032 mRNA. Translation: BAC31138.1.
AK046590 mRNA. Translation: BAE20655.1.
AL591136 Genomic DNA. Translation: CAI51872.1.
CCDSiCCDS36234.1.
RefSeqiNP_080461.3. NM_026185.4.
UniGeneiMm.432526.
Mm.487555.

3D structure databases

ProteinModelPortaliQ5F2F2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091541.

Protein family/group databases

ESTHERimouse-ABH15. abh_upf0017.

PTM databases

iPTMnetiQ5F2F2.
PhosphoSiteiQ5F2F2.

Proteomic databases

EPDiQ5F2F2.
MaxQBiQ5F2F2.
PaxDbiQ5F2F2.
PRIDEiQ5F2F2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000094004; ENSMUSP00000091541; ENSMUSG00000000686.
GeneIDi67477.
KEGGimmu:67477.
UCSCiuc007kha.1. mouse.

Organism-specific databases

CTDi116236.
MGIiMGI:1914727. Abhd15.

Phylogenomic databases

eggNOGiKOG1838. Eukaryota.
COG0429. LUCA.
GeneTreeiENSGT00530000062981.
HOGENOMiHOG000033769.
InParanoidiQ5F2F2.
KOiK13707.
OMAiETLFCHT.
OrthoDBiEOG7J70FM.
PhylomeDBiQ5F2F2.
TreeFamiTF332985.

Miscellaneous databases

PROiQ5F2F2.
SOURCEiSearch...

Gene expression databases

BgeeiQ5F2F2.
ExpressionAtlasiQ5F2F2. baseline and differential.
GenevisibleiQ5F2F2. MM.

Family and domain databases

Gene3Di3.40.50.1820. 2 hits.
InterProiIPR029058. AB_hydrolase.
IPR012020. ABHD4.
[Graphical view]
PIRSFiPIRSF005211. Ab_hydro_YheT. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Adipose tissue, Liver and Thymus.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brown adipose tissue and Liver.

Entry informationi

Entry nameiABH15_MOUSE
AccessioniPrimary (citable) accession number: Q5F2F2
Secondary accession number(s): Q3V371
, Q8C9I5, Q8CF57, Q9CU23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: March 15, 2005
Last modified: June 8, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.