Q5EZC5 (ALTA1_PLETA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Allergen Ste b 1

Alternative name(s):
Alt a 1-like protein
Allergen=Ste b 1

Gene names

Name:

alta1

Organism

Pleospora tarda (Stemphylium botryosum)

Taxonomic identifier

120510 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › dothideomyceta › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Pleosporaceae › Pleospora

Protein attributes

Sequence length	137 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Homodimer; disulfide-linked By similarity. UniProtKB P79085
Subcellular location	Secreted By similarity UniProtKB P79085.
Allergenic properties	Causes an allergic reaction in human.
Miscellaneous	On the 2D-gel the determined pI of this protein is: 4.67. Ref.2
Sequence similarities	Belongs to the ALTA1 family.
Mass spectrometry	Molecular mass is 15001 Da from positions 19 - ?. Determined by MALDI. Ref.2

Ontologies

Keywords
Cellular component	Secreted
Disease	Allergen
Domain	Signal
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	‹1 – 18	›18	Potential
	Chain	19 – 137	119	Allergen Ste b 1		PRO_0000320211
Experimental info
	Sequence conflict	39	1	S → Y AA sequence Ref.2
	Sequence conflict	52	1	S → G AA sequence Ref.2
	Sequence conflict	60	1	E → G AA sequence Ref.2
	Sequence conflict	77 – 81	5	DKFYP → HKWYS AA sequence Ref.2
	Sequence conflict	87	1	S → F AA sequence Ref.2
	Sequence conflict	91 – 93	3	AFQ → SFD AA sequence Ref.2
	Non-terminal residue	1	1
	Non-terminal residue	137	1

Sequences

	Sequence		Length	Mass (Da)
	Q5EZC5 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 4420CE1B8F63358E	FASTA	137	14,790
	10 20 30 40 50 60 ALFAAAGLAA AAPFETRQDY ASCPVSTQGD YVWKISEFSG RKPEGTYYNS LSFNIKATNE 70 80 90 100 110 120 GTLDFTCSAQ ADKLEDDKFY PCGENSSMSF AFQSDRNGLL FRQDVSNDIT YVATATLPNY 130 CRAGGDGPKD VICQGAS

References

[1]	"Alt a 1 allergen homologs from Alternaria and related taxa: analysis of phylogenetic content and secondary structure." Hong S.G., Cramer R.A., Lawrence C.B., Pryor B.M. Fungal Genet. Biol. 42:119-129(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: BMP 0360.
[2]	Gutierrez A., Postigo I., Sunen E., Guisantes J.A., Martinez J. Submitted (JAN-2008) to UniProtKB Cited for: PROTEIN SEQUENCE OF 35-96, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY563274 Genomic DNA. Translation: AAT66565.1.
3D structure databases
ModBase	Search...
Protein family/group databases
Allergome	2636. Ste b 1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ALTA1_PLETA

Accession

Primary (citable) accession number: Q5EZC5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	March 15, 2005
Last modified:	October 19, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program