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Protein

Allergen Ste b 1

Gene

alta1

Organism
Pleospora tarda (Stemphylium botryosum)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

On the 2D-gel the determined pI of this protein is: 4.67.

Names & Taxonomyi

Protein namesi
Recommended name:
Allergen Ste b 1
Alternative name(s):
Alt a 1-like protein
Allergen: Ste b 1
Gene namesi
Name:alta1
OrganismiPleospora tarda (Stemphylium botryosum)
Taxonomic identifieri120510 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePleosporaceaeStemphylium

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei2636. Ste b 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei‹1 – 18Sequence analysisAdd BLAST›18
ChainiPRO_000032021119 – 137Allergen Ste b 1Add BLAST119

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Homodimer; disulfide-linked.By similarity

Structurei

3D structure databases

SMRiQ5EZC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 133AltA1Sequence analysisAdd BLAST99

Sequence similaritiesi

Belongs to the ALTA1 family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR032382. AltA1.
PfamiView protein in Pfam
PF16541. AltA1. 1 hit.

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5EZC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ALFAAAGLAA AAPFETRQDY ASCPVSTQGD YVWKISEFSG RKPEGTYYNS
60 70 80 90 100
LSFNIKATNE GTLDFTCSAQ ADKLEDDKFY PCGENSSMSF AFQSDRNGLL
110 120 130
FRQDVSNDIT YVATATLPNY CRAGGDGPKD VICQGAS
Length:137
Mass (Da):14,790
Last modified:March 15, 2005 - v1
Checksum:i4420CE1B8F63358E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Sequence conflicti39S → Y AA sequence (Ref. 2) Curated1
Sequence conflicti52S → G AA sequence (Ref. 2) Curated1
Sequence conflicti60E → G AA sequence (Ref. 2) Curated1
Sequence conflicti77 – 81DKFYP → HKWYS AA sequence (Ref. 2) Curated5
Sequence conflicti87S → F AA sequence (Ref. 2) Curated1
Sequence conflicti91 – 93AFQ → SFD AA sequence (Ref. 2) Curated3
Non-terminal residuei137Imported1

Mass spectrometryi

Molecular mass is 15001 Da from positions 19 - ?. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY563274 Genomic DNA. Translation: AAT66565.1.

Similar proteinsi

Entry informationi

Entry nameiALTA1_PLETA
AccessioniPrimary (citable) accession number: Q5EZC5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: March 15, 2005
Last modified: September 27, 2017
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families