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Protein
Submitted name:

Glucose transporter 9b

Gene

Slc2a9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glucose transmembrane transport Source: GOC
  • glucose transport Source: MGI
  • organic acid transmembrane transport Source: MGI
  • urate metabolic process Source: MGI
Complete GO annotation...

Keywords - Biological processi

Sugar transportImported, Transport

Protein family/group databases

TCDBi2.A.1.1.47. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Submitted name:
Glucose transporter 9bImported
Gene namesi
Name:Slc2a9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2152844. Slc2a9.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 3920HelicalSequence analysisAdd
BLAST
Transmembranei74 – 9421HelicalSequence analysisAdd
BLAST
Transmembranei106 – 12823HelicalSequence analysisAdd
BLAST
Transmembranei134 – 15522HelicalSequence analysisAdd
BLAST
Transmembranei167 – 18519HelicalSequence analysisAdd
BLAST
Transmembranei197 – 21822HelicalSequence analysisAdd
BLAST
Transmembranei283 – 30422HelicalSequence analysisAdd
BLAST
Transmembranei319 – 34123HelicalSequence analysisAdd
BLAST
Transmembranei348 – 37023HelicalSequence analysisAdd
BLAST
Transmembranei376 – 40328HelicalSequence analysisAdd
BLAST
Transmembranei415 – 43824HelicalSequence analysisAdd
BLAST
Transmembranei444 – 46522HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ5ERC7.

Expressioni

Gene expression databases

GenevisibleiQ5ERC7. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063352.

Structurei

3D structure databases

ProteinModelPortaliQ5ERC7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini26 – 469444MFSInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the major facilitator superfamily.SAAS annotation
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
HOVERGENiHBG014816.
KOiK08146.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ERC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSEKNSAE TKESQRKWSF SLVVAALVGA FGSSFLYGYN LSVVNAPTPY
60 70 80 90 100
IKAFYNGTWY RRHGQPIDPD TLTLLWSVTV SIFAIGGLVG TLMVKMIGKF
110 120 130 140 150
LGRKSTLLVN NGFAISAALL MACSLRAGTF EMLIVGRFIM GVDGGIALSA
160 170 180 190 200
LPMYLNEISP KEIRGSLGQV TAIFICIGVF SGQLLGLPEL LGRESTWPYL
210 220 230 240 250
FGVIIVPALV QLASLPFLPE SPRYLLFEKH DEAGAMKAFQ TFLGKADVSQ
260 270 280 290 300
ELEEALAESR VQRNLRLVSV LELLRAPFVR WQVITVIITM ASYQLCGLNA
310 320 330 340 350
IWFYTNSIFG KAGIPQDKIP YITLSTGGIE TLAAIFSGLV IERLGRGPLL
360 370 380 390 400
IGGFGLMALF FGTLTATLTL QDQAPWVPYL SIVCILAIIA SFCSGPGGIP
410 420 430 440 450
FILTGEFFQQ SERPAAFMIA GTVNWLSNFA VGLLFPFIQK SLDSYCFLVF
460 470 480 490 500
ATICIAGATY FYFVLPETKN RTHAEISQAF AKRNKAQPPE VKADSAMTEE
510 520
KANSQTEPDS SSTLDSYGQN KIV
Length:523
Mass (Da):57,044
Last modified:March 15, 2005 - v1
Checksum:i9216757422FE2FF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY776155 mRNA. Translation: AAW78908.1.
RefSeqiNP_001012363.2. NM_001012363.2.
UniGeneiMm.260137.

Genome annotation databases

GeneIDi117591.
KEGGimmu:117591.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY776155 mRNA. Translation: AAW78908.1.
RefSeqiNP_001012363.2. NM_001012363.2.
UniGeneiMm.260137.

3D structure databases

ProteinModelPortaliQ5ERC7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063352.

Protein family/group databases

TCDBi2.A.1.1.47. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiQ5ERC7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi117591.
KEGGimmu:117591.

Organism-specific databases

CTDi56606.
MGIiMGI:2152844. Slc2a9.

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
HOVERGENiHBG014816.
KOiK08146.

Miscellaneous databases

ChiTaRSiSlc2a9. mouse.
SOURCEiSearch...

Gene expression databases

GenevisibleiQ5ERC7. MM.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Mouse glucose transporter 9 splice variants are expressed in adult liver and kidney and are up-regulated in diabetes."
    Keembiyehetty C., Augustin R., Carayannopoulos M.O., Steer S., Manolescu A., Cheeseman C.I., Moley K.H.
    Mol. Endocrinol. 20:686-697(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6J x SJL F1Imported.

Entry informationi

Entry nameiQ5ERC7_MOUSE
AccessioniPrimary (citable) accession number: Q5ERC7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: June 8, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.