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Reviewed, UniProtKB/Swiss-Prot Q5EMU8 (MTLD_MAGGR)

Last modified November 3, 2009. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Mannitol-1-phosphate 5-dehydrogenase
      Short name=M1PDH
      Short name=MPDH
      Short name=MPD
    EC=1.1.1.17
Gene names
ORF Names: MGG_10503
OrganismMagnaporthe grisea (Rice blast fungus) (Pyricularia grisea) [Complete proteome]
Taxonomic identifier148305 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeMagnaporthalesMagnaporthaceaeMagnaporthe

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway By similarity.

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH.

Subunit structure

Monomer By similarity.

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Mannitol-1-phosphate 5-dehydrogenase
PRO_0000371528

Regions

Nucleotide binding12 – 2312NAD By similarity

Sites

Active site2211 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5EMU8-1 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: AAB005CB5590EADE

FASTA40044,518
        10         20         30         40         50         60 
MSQTNGTHTK KAVHFGAGNI GRGFVACFLH NSGYEVVFAD VTDRTCDALN NQTSYKVIEV 

        70         80         90        100        110        120 
GAEGTEEKTI TNYRAINSKT KEDELLQEIA TADVVTCSVG PNILKFIAPV IAKGLDMRSE 

       130        140        150        160        170        180 
ELKPAAVIAC ENAIGATDTL AEHIKEHLPA TRVEDLSTRA RFANSAIDRI VPAQDPNSGL 

       190        200        210        220        230        240 
DVKLEKFYEW VVDRTPFADH EVPSIEGIHW VDNLEPYIER KLYTVNTGHA TAAYHGYNRQ 

       250        260        270        280        290        300 
KRTVYDALQD REIQSEVRRA LENTSKLITA KHGINPEEQQ AYVRKIMTRI GNPHLEDAVE 

       310        320        330        340        350        360 
RVGRAPLRKL SRKERFVGPA AELAEKGEDC SALLDAAEMA LRFQNVEEDA ESKELAKIMA 

       370        380        390        400 
ENSAEQVVSQ VCGLQPSEKL YPKMVEIVHR VQQDSMDDTE 

« Hide

Cross-references

Sequence databases

AY849685 mRNA. Translation: AAX07705.1.
CH476786 Genomic DNA. Translation: EDK06587.1.
RefSeqXP_366284.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2682115.
KEGGmgr:MGG_10503.
NMPDRfig|242507.1.peg.8023.

Phylogenomic databases

OMAVDRIVPN.

Family and domain databases

InterProIPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR000669. Mannitol_DH_core.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
PROSITEPS00974. MANNITOL_DHGENASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_MAGGR
AccessionPrimary (citable) accession number: Q5EMU8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: March 15, 2005
Last modified: November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents