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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi41 ↔ 115Combined sources
Disulfide bondi169 ↔ 225Combined sources

Proteomic databases

PaxDbiQ5EBM2.
PRIDEiQ5EBM2.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2I5YX-ray2.20H/R21-243[»]
ProteinModelPortaliQ5EBM2.
SMRiQ5EBM2. Positions 20-519.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Immunoglobulin domainSAAS annotation

Phylogenomic databases

eggNOGiNOG313034.
HOVERGENiHBG005814.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5EBM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDCTWRILLL VAVATGTHAQ VQLVQSGAEV KKPGASVKVS CEVSGHTLTE
60 70 80 90 100
LSRHWVRQAP GKGLEWMGGF DPEDGETVYA QTFQGRVTMT EDTSTDTAYM
110 120 130 140 150
DLSNLRSDDT AVYYCATGVY DVLTGYSRFD YWGQGTQVTV SSASTKGPSV
160 170 180 190 200
FPLAPCSRST SGGTAALGCL VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ
210 220 230 240 250
SSGLYSLSSV VTVPSSSLGT QTYTCNVNHK PSNTKVDKRV ELKTPLGDTT
260 270 280 290 300
HTCPRCPEPK SCDTPPPCPR CPEPKSCDTP PPCPRCPEPK SCDTPPPCPR
310 320 330 340 350
CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVQFKWY
360 370 380 390 400
VDGVEVHNAK TKPREEQYNS TFRVVSVLTV LHQDWLNGKE YKCKVSNKAL
410 420 430 440 450
PAPIEKTISK TKGQPREPQV YTLPPSREEM TKNQVSLTCL VKGFYPSDIA
460 470 480 490 500
VEWESSGQPE NNYNTTPPML DSDGSFFLYS KLTVDKSRWQ QGNIFSCSVM
510
HEALHNRFTQ KSLSLSPGK
Length:519
Mass (Da):56,813
Last modified:March 15, 2005 - v1
Checksum:i988C5C2F92B9E34C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089421 mRNA. Translation: AAH89421.1.
UniGeneiHs.510635.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089421 mRNA. Translation: AAH89421.1.
UniGeneiHs.510635.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2I5YX-ray2.20H/R21-243[»]
ProteinModelPortaliQ5EBM2.
SMRiQ5EBM2. Positions 20-519.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ5EBM2.
PRIDEiQ5EBM2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiNOG313034.
HOVERGENiHBG005814.

Miscellaneous databases

NextBioi35539127.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LymphImported.
  2. "Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein."
    Stricher F., Huang C.C., Descours A., Duquesnoy S., Combes O., Decker J.M., Kwon Y.D., Lusso P., Shaw G.M., Vita C., Kwong P.D., Martin L.
    J. Mol. Biol. 382:510-524(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 21-243, ACTIVE SITE.

Entry informationi

Entry nameiQ5EBM2_HUMAN
AccessioniPrimary (citable) accession number: Q5EBM2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: April 29, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.