prss1

Functionⁱ

GO - Molecular functionⁱ

serine-type endopeptidase activity Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Molecular function

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	S01.387.

MEROPSⁱ

S01.387.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MGC108396 proteinImported
Gene namesⁱ	Name:prss1Imported Synonyms:MGC108396Imported ORF Names:XENTR_v90029047mgImported
Organismⁱ	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifierⁱ	8364 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana
Proteomesⁱ	UP000008143 Componentⁱ: Unassembled WGS sequence

Organism-specific databases

Xenbaseⁱ	XB-GENE-5776262. prss1.

Xenbaseⁱ

XB-GENE-5776262. prss1.

PTM / Processingⁱ

Keywords - PTMⁱ

Disulfide bondSAAS annotation

Proteomic databases

PaxDbⁱ	Q5EBE2.

PaxDbⁱ

Q5EBE2.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	22 – 242	Peptidase S1InterPro annotationAdd BLAST		221

Sequence similaritiesⁱ

Belongs to the peptidase S1 family.SAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG3627. Eukaryota. COG5640. LUCA.
HOGENOMⁱ	HOG000251820.
HOVERGENⁱ	HBG013304.
KEGG Orthology (KO) More...KOⁱ	K01312.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0DF7.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00190. Tryp_SPc. 1 hit.
InterProⁱ	View protein in InterPro IPR009003. Peptidase_S1_PA. IPR001314. Peptidase_S1A. IPR001254. Trypsin_dom. IPR018114. TRYPSIN_HIS. IPR033116. TRYPSIN_SER.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00089. Trypsin. 1 hit.
PRINTSⁱ	PR00722. CHYMOTRYPSIN.
SMARTⁱ	View protein in SMART SM00020. Tryp_SPc. 1 hit.
SUPFAMⁱ	SSF50494. SSF50494. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50240. TRYPSIN_DOM. 1 hit. PS00134. TRYPSIN_HIS. 1 hit. PS00135. TRYPSIN_SER. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5EBE2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKFLIVLVLL GAAVAFEDDD KIVGGFTCTK NAVPYQVSLN AGYHFCGGSL 
        60         70         80         90        100
INSQWVVSAA HCYKSRIQVR LGEHNIAVNE GTEQFIESQK VIKHPSYNSR 
       110        120        130        140        150
NLDNDIMLIK LSTTARLSSN IQSVPLPSAC ASAGTNCLIS GWGNTLSSGT 
       160        170        180        190        200
NYPDLLQCLN APILTASECS NSYPGEITNN MFCAGFLAGG KDSCQGDSGG 
       210        220        230        240 
PVVCNGQLQG VVSWGYGCAQ RNYPGVYTKV CNYVSWIQNT IAAN

Length:244

Mass (Da):26,038

Last modified:March 15, 2005 - v1

Checksum:ⁱ5302AE87A7C69B46

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC089741 mRNA. Translation: AAH89741.1. KV460722 Genomic DNA. Translation: OCA15846.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001015792.1. NM_001015792.1.
UniGeneⁱ	Str.68833.

Genome annotation databases

GeneIDⁱ	548509.
KEGGⁱ	xtr:548509.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q5EBE2	F7D9G1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	254	UniRef100_F7D9G1	Cluster: Protease, serine 1	2

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q5EBE2	P70059 A0A1L8FHX9 Q7SZT1 Q4QR60 F7D9G1 Q3B898 Q05AV3 Q6GNU2 A0A1L8FDN4 UPI00084DF72E	Xenopus laevis (African clawed frog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	244	UniRef90_P70059	Cluster: Trypsin	11

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q5EBE2	P00760 UPI0000032F17 UPI000951D0BE UPI000011149D UPI0000112FBD UPI0000110A36 UPI000011184A UPI00072F6C77 L8HNC2 L8HM14 +263	Bos taurus (Bovine) Bos indicus (Zebu) Ovis aries (Sheep) Bos mutus (wild yak) Odocoileus virginianus texanus Bubalus bubalis (Domestic water buffalo) Bison bison bison Pantholops hodgsonii (Chiru) (Tibetan antelope) Capra hircus (Goat) Poecilia reticulata (Guppy) (Acanthophacelus reticulatus) And more	246	UniRef50_P00760	Cluster: Cationic trypsin	274

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC089741 mRNA. Translation: AAH89741.1. KV460722 Genomic DNA. Translation: OCA15846.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001015792.1. NM_001015792.1.
UniGeneⁱ	Str.68833.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	S01.387.

MEROPSⁱ

S01.387.

Proteomic databases

PaxDbⁱ	Q5EBE2.

PaxDbⁱ

Q5EBE2.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	548509.
KEGGⁱ	xtr:548509.

Organism-specific databases

Xenbaseⁱ	XB-GENE-5776262. prss1.

Xenbaseⁱ

XB-GENE-5776262. prss1.

Phylogenomic databases

eggNOGⁱ	KOG3627. Eukaryota. COG5640. LUCA.
HOGENOMⁱ	HOG000251820.
HOVERGENⁱ	HBG013304.
KEGG Orthology (KO) More...KOⁱ	K01312.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0DF7.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00190. Tryp_SPc. 1 hit.
InterProⁱ	View protein in InterPro IPR009003. Peptidase_S1_PA. IPR001314. Peptidase_S1A. IPR001254. Trypsin_dom. IPR018114. TRYPSIN_HIS. IPR033116. TRYPSIN_SER.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00089. Trypsin. 1 hit.
PRINTSⁱ	PR00722. CHYMOTRYPSIN.
SMARTⁱ	View protein in SMART SM00020. Tryp_SPc. 1 hit.
SUPFAMⁱ	SSF50494. SSF50494. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50240. TRYPSIN_DOM. 1 hit. PS00134. TRYPSIN_HIS. 1 hit. PS00135. TRYPSIN_SER. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5EBE2_XENTR
Accessionⁱ	Q5EBE2Primary (citable) accession number: Q5EBE2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 15, 2005
	Last sequence update:	March 15, 2005
	Last modified:	August 30, 2017
	This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q5EBE2 (Q5EBE2_XENTR)

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MGC108396 protein

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Protein family/group databases

Names & Taxonomyⁱ

Organism-specific databases

PTM / Processingⁱ

Keywords - PTMⁱ

Proteomic databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5EBE2 (Q5EBE2_XENTR)

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MGC108396 protein

prss1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ