prss1

Functionⁱ

GO - Molecular functionⁱ

serine-type endopeptidase activity Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase, Protease, Serine proteaseUniRule annotation

Molecular function

Hydrolase, Protease, Serine proteaseUniRule annotation

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	S01.387

MEROPSⁱ

S01.387

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MGC108396 proteinImported
Gene namesⁱ	Name:prss1Imported Synonyms:MGC108396Imported ORF Names:XENTR_v90029047mgImported
Organismⁱ	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifierⁱ	8364 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana
Proteomesⁱ	UP000008143 Componentⁱ: Unassembled WGS sequence

Organism-specific databases

Xenbaseⁱ	XB-GENE-5776262 prss1

Xenbaseⁱ

XB-GENE-5776262 prss1

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 15	Sequence analysisAdd BLAST		15
ChainⁱPRO_5014309757	16 – 244	Sequence analysisAdd BLAST		229

Keywords - PTMⁱ

Disulfide bondSAAS annotation

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	22 – 242	Peptidase S1InterPro annotationAdd BLAST		221

Sequence similaritiesⁱ

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domainⁱ

SignalSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG3627 Eukaryota COG5640 LUCA
HOGENOMⁱ	HOG000251820
HOVERGENⁱ	HBG013304
KEGG Orthology (KO) More...KOⁱ	K01312
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0DF7

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00190 Tryp_SPc, 1 hit
InterProⁱ	View protein in InterPro IPR009003 Peptidase_S1_PA IPR001314 Peptidase_S1A IPR001254 Trypsin_dom IPR018114 TRYPSIN_HIS IPR033116 TRYPSIN_SER
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00089 Trypsin, 1 hit
PRINTSⁱ	PR00722 CHYMOTRYPSIN
SMARTⁱ	View protein in SMART SM00020 Tryp_SPc, 1 hit
SUPFAMⁱ	SSF50494 SSF50494, 1 hit
PROSITEⁱ	View protein in PROSITE PS50240 TRYPSIN_DOM, 1 hit PS00134 TRYPSIN_HIS, 1 hit PS00135 TRYPSIN_SER, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5EBE2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKFLIVLVLL GAAVAFEDDD KIVGGFTCTK NAVPYQVSLN AGYHFCGGSL 
        60         70         80         90        100
INSQWVVSAA HCYKSRIQVR LGEHNIAVNE GTEQFIESQK VIKHPSYNSR 
       110        120        130        140        150
NLDNDIMLIK LSTTARLSSN IQSVPLPSAC ASAGTNCLIS GWGNTLSSGT 
       160        170        180        190        200
NYPDLLQCLN APILTASECS NSYPGEITNN MFCAGFLAGG KDSCQGDSGG 
       210        220        230        240 
PVVCNGQLQG VVSWGYGCAQ RNYPGVYTKV CNYVSWIQNT IAAN

Length:244

Mass (Da):26,038

Last modified:March 15, 2005 - v1

Checksum:ⁱ5302AE87A7C69B46

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC089741 mRNA Translation: AAH89741.1 KV460722 Genomic DNA Translation: OCA15846.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001015792.1, NM_001015792.1
UniGeneⁱ	Str.68833

Genome annotation databases

GeneIDⁱ	548509
KEGGⁱ	xtr:548509

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5EBE2	F7D9G1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	254	UniRef100_F7D9G1	Cluster: Serine protease 1	2

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5EBE2	P70059 A0A1L8FHX9 Q7SZT1 Q4QR60 F7D9G1 Q3B898 Q05AV3 Q6GNU2 A0A1L8FDN4 UPI00084DF72E	Xenopus laevis (African clawed frog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	244	UniRef90_P70059	Cluster: Trypsin	11

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5EBE2	P00760 UPI000011149D UPI0000112FBD UPI000951D0BE UPI0000110A36 UPI000011184A UPI0000032F17 UPI00072F6C77 L8HNC2 L8HM14 +269	Bos taurus (Bovine) Bos indicus (Zebu) Ovis aries (Sheep) Bos mutus (wild yak) Odocoileus virginianus texanus Bubalus bubalis (Domestic water buffalo) Bison bison bison Pantholops hodgsonii (Chiru) (Tibetan antelope) Capra hircus (Goat) Poecilia reticulata (Guppy) (Acanthophacelus reticulatus) And more	246	UniRef50_P00760	Cluster: Cationic trypsin	280

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC089741 mRNA Translation: AAH89741.1 KV460722 Genomic DNA Translation: OCA15846.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001015792.1, NM_001015792.1
UniGeneⁱ	Str.68833

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	S01.387

MEROPSⁱ

S01.387

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	548509
KEGGⁱ	xtr:548509

Organism-specific databases

Xenbaseⁱ	XB-GENE-5776262 prss1

Xenbaseⁱ

XB-GENE-5776262 prss1

Phylogenomic databases

eggNOGⁱ	KOG3627 Eukaryota COG5640 LUCA
HOGENOMⁱ	HOG000251820
HOVERGENⁱ	HBG013304
KEGG Orthology (KO) More...KOⁱ	K01312
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0DF7

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00190 Tryp_SPc, 1 hit
InterProⁱ	View protein in InterPro IPR009003 Peptidase_S1_PA IPR001314 Peptidase_S1A IPR001254 Trypsin_dom IPR018114 TRYPSIN_HIS IPR033116 TRYPSIN_SER
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00089 Trypsin, 1 hit
PRINTSⁱ	PR00722 CHYMOTRYPSIN
SMARTⁱ	View protein in SMART SM00020 Tryp_SPc, 1 hit
SUPFAMⁱ	SSF50494 SSF50494, 1 hit
PROSITEⁱ	View protein in PROSITE PS50240 TRYPSIN_DOM, 1 hit PS00134 TRYPSIN_HIS, 1 hit PS00135 TRYPSIN_SER, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5EBE2_XENTR
Accessionⁱ	Q5EBE2Primary (citable) accession number: Q5EBE2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 15, 2005
	Last sequence update:	March 15, 2005
	Last modified:	April 25, 2018
	This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q5EBE2 (Q5EBE2_XENTR)

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MGC108396 protein

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Functionⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Protein family/group databases

Names & Taxonomyⁱ

Organism-specific databases

PTM / Processingⁱ

Molecule processing

Keywords - PTMⁱ

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5EBE2 (Q5EBE2_XENTR)

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MGC108396 protein

prss1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ