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Protein
Submitted name:

G protein-coupled receptor TYMSTR

Gene

CXCR6

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-BTA-380108. Chemokine receptors bind chemokines.
R-BTA-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor TYMSTRImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CXCR6Imported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 22

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei31 – 5828HelicalSequence analysisAdd
BLAST
Transmembranei70 – 9122HelicalSequence analysisAdd
BLAST
Transmembranei103 – 12422HelicalSequence analysisAdd
BLAST
Transmembranei145 – 16824HelicalSequence analysisAdd
BLAST
Transmembranei188 – 20922HelicalSequence analysisAdd
BLAST
Transmembranei230 – 24718HelicalSequence analysisAdd
BLAST
Transmembranei267 – 28923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSBTAG00000015708.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000020855.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini47 – 286240G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118785.
HOVERGENiHBG106917.
KOiK04191.
OMAiTPFNLVK.
OrthoDBiEOG091G0D3V.
TreeFamiTF330966.

Family and domain databases

InterProiIPR002235. Chemokine_CXCR6.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01105. CXCCHMKINER6.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5EA94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEYNYEDLG FFNGSNDSSQ GHQDFLRFSK FFLPCMYVVV FTCGLVGNSL
60 70 80 90 100
VLVIYVFYQK LKSLTDVFLM NLPLADLVFV CTLPFWAYAG IHEWVFGNVM
110 120 130 140 150
CKALLGIYTL NFYTSMLVLT CITVDRFVAV VRATKAYNQQ AKRMAWGKAI
160 170 180 190 200
CSSIWVVSLL VSLPQIIYGN VLYHDKPFCG YHEAISTMVL AIQMTLGFFL
210 220 230 240 250
PLLAMILCYS VIIKTLLQAR GFRKHKSLKI IFLVVAVFLL TQTPFNLVKL
260 270 280 290 300
IRSTSWEYHT MTSFDYAITV TEAIAYLRAC LNPVLYAFVG LKFRKNFWKL
310 320 330 340
VKDAGCLPYL GVSGQHMYSE DTSRSASASH NVEATSMFHL
Length:340
Mass (Da):38,612
Last modified:March 15, 2005 - v1
Checksum:i9CA4459A8C872482
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02054509 Genomic DNA. No translation available.
BT020675 mRNA. Translation: AAX08692.1.
RefSeqiNP_001014859.1. NM_001014859.1.
UniGeneiBt.91115.

Genome annotation databases

EnsembliENSBTAT00000020855; ENSBTAP00000020855; ENSBTAG00000015708.
GeneIDi506807.
KEGGibta:506807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02054509 Genomic DNA. No translation available.
BT020675 mRNA. Translation: AAX08692.1.
RefSeqiNP_001014859.1. NM_001014859.1.
UniGeneiBt.91115.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000020855.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000020855; ENSBTAP00000020855; ENSBTAG00000015708.
GeneIDi506807.
KEGGibta:506807.

Organism-specific databases

CTDi10663.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118785.
HOVERGENiHBG106917.
KOiK04191.
OMAiTPFNLVK.
OrthoDBiEOG091G0D3V.
TreeFamiTF330966.

Enzyme and pathway databases

ReactomeiR-BTA-380108. Chemokine receptors bind chemokines.
R-BTA-418594. G alpha (i) signalling events.

Gene expression databases

BgeeiENSBTAG00000015708.

Family and domain databases

InterProiIPR002235. Chemokine_CXCR6.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01105. CXCCHMKINER6.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5EA94_BOVIN
AccessioniPrimary (citable) accession number: Q5EA94
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.