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Protein
Submitted name:

C-X-C motif chemokine receptor 6

Gene

CXCR6

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-BTA-380108. Chemokine receptors bind chemokines.
R-BTA-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
C-X-C motif chemokine receptor 6Imported
Submitted name:
G protein-coupled receptor TYMSTRImported
Gene namesi
Name:CXCR6Imported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 22

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 58HelicalSequence analysisAdd BLAST28
Transmembranei70 – 91HelicalSequence analysisAdd BLAST22
Transmembranei103 – 124HelicalSequence analysisAdd BLAST22
Transmembranei145 – 168HelicalSequence analysisAdd BLAST24
Transmembranei188 – 209HelicalSequence analysisAdd BLAST22
Transmembranei230 – 247HelicalSequence analysisAdd BLAST18
Transmembranei267 – 289HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSBTAG00000015708.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000020855.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 286G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST240

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118785.
HOVERGENiHBG106917.
KOiK04191.
OMAiTPFNLVK.
OrthoDBiEOG091G0D3V.
TreeFamiTF330966.

Family and domain databases

CDDicd15173. 7tmA_CXCR6. 1 hit.
InterProiView protein in InterPro
IPR002235. Chemokine_CXCR6.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR10489:SF785. PTHR10489:SF785. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00657. CCCHEMOKINER.
PR01105. CXCCHMKINER6.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5EA94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEYNYEDLG FFNGSNDSSQ GHQDFLRFSK FFLPCMYVVV FTCGLVGNSL
60 70 80 90 100
VLVIYVFYQK LKSLTDVFLM NLPLADLVFV CTLPFWAYAG IHEWVFGNVM
110 120 130 140 150
CKALLGIYTL NFYTSMLVLT CITVDRFVAV VRATKAYNQQ AKRMAWGKAI
160 170 180 190 200
CSSIWVVSLL VSLPQIIYGN VLYHDKPFCG YHEAISTMVL AIQMTLGFFL
210 220 230 240 250
PLLAMILCYS VIIKTLLQAR GFRKHKSLKI IFLVVAVFLL TQTPFNLVKL
260 270 280 290 300
IRSTSWEYHT MTSFDYAITV TEAIAYLRAC LNPVLYAFVG LKFRKNFWKL
310 320 330 340
VKDAGCLPYL GVSGQHMYSE DTSRSASASH NVEATSMFHL
Length:340
Mass (Da):38,612
Last modified:March 15, 2005 - v1
Checksum:i9CA4459A8C872482
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02054509 Genomic DNA. No translation available.
BT020675 mRNA. Translation: AAX08692.1.
RefSeqiNP_001014859.1. NM_001014859.1.
UniGeneiBt.91115.

Genome annotation databases

EnsembliENSBTAT00000020855; ENSBTAP00000020855; ENSBTAG00000015708.
GeneIDi506807.
KEGGibta:506807.

Similar proteinsi

Entry informationi

Entry nameiQ5EA94_BOVIN
AccessioniPrimary (citable) accession number: Q5EA94
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: August 30, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported