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Protein
Submitted name:

Peroxisome proliferative activated receptor, alpha isoform 1

Gene

PPARA

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi101 – 175Nuclear receptorPROSITE-ProRule annotationAdd BLAST75

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-BTA-383280. Nuclear Receptor transcription pathway.
R-BTA-400206. Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha).

Names & Taxonomyi

Protein namesi
Submitted name:
Peroxisome proliferative activated receptor, alpha isoform 1Imported
Submitted name:
Peroxisome proliferator activated receptor alphaImported
Gene namesi
Name:PPARAImported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSBTAG00000008063.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000010606.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 175Nuclear receptor DNA-bindingInterPro annotationAdd BLAST75

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00870000136388.
HOGENOMiHOG000261626.
HOVERGENiHBG106004.
KOiK07294.
OMAiFSFTEYQ.
OrthoDBiEOG091G05U8.
TreeFamiTF316304.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR003074. 1Cnucl_rcpt.
IPR003076. 1Cnucl_rcpt_A.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01288. PROXISOMEPAR.
PR01289. PROXISOMPAAR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5EA13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMVDTESPI GPLSPLEADD LESPLSADFL QEMGTIQEIS QSIGEDSSGS
60 70 80 90 100
FSFTEYQYLG SGPGSDGSVI TDTLSPASSP SSVSYPAVPG SAEESSSIAL
110 120 130 140 150
NIECRICGDK ASGYHYGVHA CEGCKGFFRR TIRLKLVYDK CDRSCKIQKK
160 170 180 190 200
NRNKCQYCRF HKCLSVGMSH NAIRFGRMPR SEKAKLKAEI LTCEHDLEDS
210 220 230 240 250
ETADLKSLAK RIYEAYLKNF NMNKIKARVI LAGKTNNNPP FVIHDMETLC
260 270 280 290 300
MAEKTLVAKL VANGIQNKEA EVRIFHCCQC TSVETVTELT EFAKSIPGFA
310 320 330 340 350
NLDLNDQVTL LKYGVYEAIF AMLSSVMNKD GMLVAYGNGF ITREFLKSLR
360 370 380 390 400
KPFCDIMEPK FDFAMKFNAL ELDDSDISLF VAAIICCGDR PGLLNVGHIE
410 420 430 440 450
KMQEGIVHVL KLHLQNNHPD DVFLFPKLLQ KMADLRQLVT EHAQLVQVIK
460 470
KTESDAALHP LLQEIYRDMY
Length:470
Mass (Da):52,428
Last modified:March 15, 2005 - v1
Checksum:i9F36D23325D247C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02014949 Genomic DNA. No translation available.
DAAA02014950 Genomic DNA. No translation available.
DAAA02014951 Genomic DNA. No translation available.
DAAA02014952 Genomic DNA. No translation available.
BT020756 mRNA. Translation: AAX08773.1.
RefSeqiNP_001029208.1. NM_001034036.1.
XP_005207529.1. XM_005207472.3.
XP_015326928.1. XM_015471442.1.
UniGeneiBt.18241.

Genome annotation databases

EnsembliENSBTAT00000010606; ENSBTAP00000010606; ENSBTAG00000008063.
GeneIDi281992.
KEGGibta:281992.

Similar proteinsi

Entry informationi

Entry nameiQ5EA13_BOVIN
AccessioniPrimary (citable) accession number: Q5EA13
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: August 30, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported