Q5E9Q1 (PGLT1_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein O-glucosyltransferase 1
EC=2.4.1.-

Alternative name(s):
CAP10-like 46 kDa protein
KTEL motif-containing protein 1

Gene names

Name:	POGLUT1
Synonyms:	CLP46, KTELC1

Organism

Bos taurus (Bovine) [Reference proteome]

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	UDP-glucosyltransferase By similarity.
Pathway	Protein modification; protein glycosylation.
Subcellular location	Endoplasmic reticulum lumen By similarity.
Sequence similarities	Belongs to the glycosyltransferase 90 family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Domain	Signal
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cardiovascular system development Inferred from electronic annotation. Source: Compara protein O-linked glycosylation Inferred from electronic annotation. Source: Compara regulation of Notch signaling pathway Inferred from electronic annotation. Source: Compara
Cellular_component	endoplasmic reticulum lumen Inferred from sequence or structural similarity. Source: UniProtKB
Molecular_function	UDP-glucosyltransferase activity Inferred from sequence or structural similarity. Source: UniProtKB UDP-xylosyltransferase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 392	369	Protein O-glucosyltransferase 1		PRO_0000246684
Regions
	Motif	389 – 392	4	Prevents secretion from ER Potential
Amino acid modifications
	Glycosylation	53	1	N-linked (GlcNAc...) Potential
	Glycosylation	204	1	N-linked (GlcNAc...) Potential
	Glycosylation	373	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5E9Q1 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 59FF5C0B59429DEC	FASTA	392	46,009
	10 20 30 40 50 60 MELGVSSQLW LWLLLLLLPP VPGREKESGS KWKVFIDQIN RALENYEPCS SPNCSCYHGV 70 80 90 100 110 120 IEEDLTPFRG GISRKMMAEV VRRKLGTHYQ IIKNRLYRES DCMFPSRCSG VEHFILEVIG 130 140 150 160 170 180 RLPDMEMVIN VRDYPQVPKW MEPAIPIFSF SKTLEYHDIM YPAWTFWEGG PAVWPIYPMG 190 200 210 220 230 240 LGRWDLFRED LVRSAAQWPW KKKNSTAYFR GSRTSPERDP LILLSRKNPK LVDAEYTKNQ 250 260 270 280 290 300 AWKSMKDTLG KPAAKDVHLV DHCKYKYLFN FRGVAASFRF KHLFLCGSLV FHVGDEWLEF 310 320 330 340 350 360 FYPQLKPWVH YIPVKTDLSN VQELLQFVKA NDDVAQEIAE RGSQFILNHL KMDDITCYWE 370 380 390 NLLTEYSKFL SYNVTRRKGY DQIVPKILKI EL

References

[1]

"Characterization of 954 bovine full-CDS cDNA sequences." Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L., Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L. BMC Genomics 6:166-166(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT020869 mRNA. Translation: AAX08886.1.
IPI	IPI00711288.
RefSeq	NP_001014903.1. NM_001014903.1.
UniGene	Bt.33308.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	9913.ENSBTAP00000011287.
Protein family/group databases
CAZy	GT90. Glycosyltransferase Family 90.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000011287; ENSBTAP00000011287; ENSBTAG00000008562.
GeneID	511862.
KEGG	bta:511862.
Organism-specific databases
CTD	56983.
Phylogenomic databases
eggNOG	NOG248922.
GeneTree	ENSGT00530000063132.
HOVERGEN	HBG069044.
InParanoid	Q5E9Q1.
KO	K13667.
OMA	WGATEIT.
OrthoDB	EOG4SN1P0.
Enzyme and pathway databases
UniPathway	UPA00378.
Family and domain databases
InterPro	IPR006598. LipoPS_modifying. [Graphical view]
Pfam	PF05686. Glyco_transf_90. 1 hit. [Graphical view]
SMART	SM00672. CAP10. 1 hit. [Graphical view]
PROSITE	PS00014. ER_TARGET. False negative. [Graphical view]
ProtoNet	Search...
Other
NextBio	20870134.

Entry information

Entry name

PGLT1_BOVIN

Accession

Primary (citable) accession number: Q5E9Q1

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	March 15, 2005
Last modified:	May 29, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program