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Protein

Cyclin-G1

Gene

CCNG1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Cyclin

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-G1
Gene namesi
Name:CCNG1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 7

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 295295Cyclin-G1PRO_0000282331Add
BLAST

Proteomic databases

PaxDbiQ5E9I1.
PRIDEiQ5E9I1.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000008669.

Structurei

3D structure databases

ProteinModelPortaliQ5E9I1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family. Cyclin G subfamily.Curated

Phylogenomic databases

eggNOGiKOG0653. Eukaryota.
COG5024. LUCA.
GeneTreeiENSGT00530000062971.
HOGENOMiHOG000059559.
HOVERGENiHBG050839.
InParanoidiQ5E9I1.
KOiK10145.
OMAiSDMMRME.
OrthoDBiEOG7HB59M.
TreeFamiTF101007.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR028860. CCNG1.
IPR013763. Cyclin-like.
IPR006671. Cyclin_N.
[Graphical view]
PANTHERiPTHR10177:SF59. PTHR10177:SF59. 2 hits.
PfamiPF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5E9I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEVLTTTDS QKLLHQLNAL LEQELRCQPK VCGLRLIESA HDNGLRMTAR
60 70 80 90 100
LRDFEVKDLL SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS
110 120 130 140 150
CFYLAVKSTE EERNVPLATD LIRISQYRFT VSDLMRMEKI VLEKVCWKVK
160 170 180 190 200
ATTAFQFLQL YYSLLQENVP HERKSSLNFE RLEAQLKACY CRIIFSKAKP
210 220 230 240 250
SVLALSIIAL EIQAQKYIEL TEGVERLQKH SKISGRDLTF WQELVSKCLA
260 270 280 290
EYSSNKCAKP NVQKLKWIVS GRTARQLRHS YYRITHLPTI PETVP
Length:295
Mass (Da):34,107
Last modified:March 15, 2005 - v1
Checksum:i551AA72198F9224E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT020939 mRNA. Translation: AAX08956.1.
BT021183 mRNA. Translation: AAX31365.1.
BC102254 mRNA. Translation: AAI02255.1.
BC150004 mRNA. Translation: AAI50005.1.
RefSeqiNP_001013382.1. NM_001013364.1.
UniGeneiBt.62415.

Genome annotation databases

EnsembliENSBTAT00000008669; ENSBTAP00000008669; ENSBTAG00000006607.
GeneIDi281671.
KEGGibta:281671.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT020939 mRNA. Translation: AAX08956.1.
BT021183 mRNA. Translation: AAX31365.1.
BC102254 mRNA. Translation: AAI02255.1.
BC150004 mRNA. Translation: AAI50005.1.
RefSeqiNP_001013382.1. NM_001013364.1.
UniGeneiBt.62415.

3D structure databases

ProteinModelPortaliQ5E9I1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000008669.

Proteomic databases

PaxDbiQ5E9I1.
PRIDEiQ5E9I1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000008669; ENSBTAP00000008669; ENSBTAG00000006607.
GeneIDi281671.
KEGGibta:281671.

Organism-specific databases

CTDi900.

Phylogenomic databases

eggNOGiKOG0653. Eukaryota.
COG5024. LUCA.
GeneTreeiENSGT00530000062971.
HOGENOMiHOG000059559.
HOVERGENiHBG050839.
InParanoidiQ5E9I1.
KOiK10145.
OMAiSDMMRME.
OrthoDBiEOG7HB59M.
TreeFamiTF101007.

Miscellaneous databases

NextBioi20805600.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR028860. CCNG1.
IPR013763. Cyclin-like.
IPR006671. Cyclin_N.
[Graphical view]
PANTHERiPTHR10177:SF59. PTHR10177:SF59. 2 hits.
PfamiPF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. NIH - Mammalian Gene Collection (MGC) project
    Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus and Hereford.
    Tissue: Hypothalamus and Ileum.

Entry informationi

Entry nameiCCNG1_BOVIN
AccessioniPrimary (citable) accession number: Q5E9I1
Secondary accession number(s): A6QQV2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: March 15, 2005
Last modified: November 11, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.