Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Translation initiation factor eIF-2B subunit beta

Gene

EIF2B2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor eIF-2B subunit beta
Alternative name(s):
eIF-2B GDP-GTP exchange factor subunit beta
Gene namesi
Name:EIF2B2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 10

Organism-specific databases

VGNCiVGNC:28385 EIF2B2

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002234701 – 351Translation initiation factor eIF-2B subunit betaAdd BLAST351

Proteomic databases

PaxDbiQ5E9B4
PRIDEiQ5E9B4

Expressioni

Gene expression databases

BgeeiENSBTAG00000008664

Interactioni

Subunit structurei

Complex of five different subunits; alpha, beta, gamma, delta and epsilon.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000011424

Structurei

3D structure databases

ProteinModelPortaliQ5E9B4
SMRiQ5E9B4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1465 Eukaryota
COG1184 LUCA
GeneTreeiENSGT00550000074908
HOGENOMiHOG000208487
HOVERGENiHBG051458
InParanoidiQ5E9B4
KOiK03754
OMAiSNAGELM
OrthoDBiEOG091G09RO
TreeFamiTF101506

Family and domain databases

InterProiView protein in InterPro
IPR000649 IF-2B-related
IPR037171 NagB/RpiA_transferase-like
PfamiView protein in Pfam
PF01008 IF-2B, 1 hit
SUPFAMiSSF100950 SSF100950, 2 hits

Sequencei

Sequence statusi: Complete.

Q5E9B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGAAAKGSE LSERIESFVE ALKRGGGRRS SEDMARETLG LLRRIITDHR
60 70 80 90 100
WSNAGELMEL IRREGRRMTA AQPSETTVGN MVRRVLRIIR EEYGRLHGRS
110 120 130 140 150
DESDQQESLH KLLTSGGLSE DFRSHYAQLQ SNIIEAINEL LVELEGTTEN
160 170 180 190 200
IAAQALEHIH SNEVIMTIGF SRTVEAFLRE AARKRKFHVI VAECAPFCQG
210 220 230 240 250
HEMAVNLSKA GIETTVMTDA AIFAVMSRVN KVIIGTKTIL ANGALRAVAG
260 270 280 290 300
THTLALAAKH HSTPLIVCAP MFKLSPQFPN EEDSFHKFVA PEEVLPFTEG
310 320 330 340 350
DILEKVSVHC PVFDYVPPEL ITLFISNIGG NAPSYIYRLM SELYHPDDHV

L
Length:351
Mass (Da):38,995
Last modified:March 15, 2005 - v1
Checksum:i557604221B37F8A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT021006 mRNA Translation: AAX09023.1
BC123823 mRNA Translation: AAI23824.1
RefSeqiNP_001015593.1, NM_001015593.1
UniGeneiBt.3050

Genome annotation databases

EnsembliENSBTAT00000011424; ENSBTAP00000011424; ENSBTAG00000008664
GeneIDi513958
KEGGibta:513958

Similar proteinsi

Entry informationi

Entry nameiEI2BB_BOVIN
AccessioniPrimary (citable) accession number: Q5E9B4
Secondary accession number(s): A4FV73
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: March 15, 2005
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health