Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q5E847 (G6PI_VIBF1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:VF_0304
OrganismVibrio fischeri (strain ATCC 700601 / ES114) [Reference proteome] [HAMAP]
Taxonomic identifier312309 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 550550Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180763

Sites

Active site3561Proton donor By similarity
Active site3871 By similarity
Active site5151 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5E847 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 515E6EEB2743024F

FASTA55060,931
        10         20         30         40         50         60 
MLKNINPTET QAWADLTAHF ETAQDFNLSD LFAADAQRFD KFSATFGQDI LVDFSKNLIT 

        70         80         90        100        110        120 
EETMKKLFAL AEQTELSSAI TAMFSGEKIN KTEGRSVLHT ALRNRSNTPV MVDGEDVMPA 

       130        140        150        160        170        180 
VNAVLEKMKG FTERLISGEW KGYTGKEITD IVNIGIGGSD LGPYMVSEAL APYKTRLNMH 

       190        200        210        220        230        240 
FVSNVDGTHI VETLKPLNPE TTLFLIASKT FTTQETMTNA HSARDWFLAE AGDQAHVAKH 

       250        260        270        280        290        300 
FAALSTNAQS VSEFGIDTDN MFEFWDWVGG RYSLWSAIGL SIALAVGFDN FIELLEGAHE 

       310        320        330        340        350        360 
VDKHFAETDL ENNVPVILAL IGLWYNNFHG AESESILPYD QYLHRFAAYF QQGNMESNGK 

       370        380        390        400        410        420 
CVDRNGNPVD YQTGPIIWGE PGTNGQHAFY QLIHQGTKLI PCDFIAPAIS HNQVGDHHQK 

       430        440        450        460        470        480 
LMSNFFAQTE ALAFGKTEET VKAEFAAAGK TEAEVAELVP FKVFEGNRPT NSILVKQVTP 

       490        500        510        520        530        540 
KTLGNLIAMY EHKIFVQGVI WNIFSFDQWG VELGKQLANQ ILPELADDKA VTSHDSSTNG 

       550 
LINAFKAFQA 

« Hide

References

[1]"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners."
Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P.
Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700601 / ES114.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000020 Genomic DNA. Translation: AAW84799.1.
RefSeqYP_203687.1. NC_006840.2.

3D structure databases

ProteinModelPortalQ5E847.
SMRQ5E847. Positions 17-546.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING312309.VF_0304.

Proteomic databases

PRIDEQ5E847.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW84799; AAW84799; VF_0304.
GeneID3277256.
KEGGvfi:VF_0304.
PATRIC20111080. VBIVibFis127983_0297.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycAFIS312309:GIWP-300-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_VIBF1
AccessionPrimary (citable) accession number: Q5E847
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 15, 2005
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways