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Q5E7S8

- GLSA_VIBF1

UniProt

Q5E7S8 - GLSA_VIBF1

Protein

Glutaminase

Gene

glsA

Organism
Vibrio fischeri (strain ATCC 700601 / ES114)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (15 Mar 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei64 – 641SubstrateUniRule annotation
    Binding sitei115 – 1151SubstrateUniRule annotation
    Binding sitei159 – 1591SubstrateUniRule annotation
    Binding sitei166 – 1661SubstrateUniRule annotation
    Binding sitei190 – 1901SubstrateUniRule annotation
    Binding sitei242 – 2421SubstrateUniRule annotation
    Binding sitei260 – 2601Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciAFIS312309:GIWP-440-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:VF_0423
    OrganismiVibrio fischeri (strain ATCC 700601 / ES114)
    Taxonomic identifieri312309 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
    ProteomesiUP000000537: Chromosome I

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306GlutaminasePRO_1000048366Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi312309.VF_0423.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5E7S8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiMSIAVWS.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5E7S8-1 [UniParc]FASTAAdd to Basket

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    MKPTKQILED ILDEVRPLIG QGKVADYIPA LACVPNDKLG IAVFTNDGEM    50
    LTAGDATECF SIQSISKALS LTLAMELYQP EELWQRVGKE PSGQAFNSLI 100
    QLEMEQGVPR NPFINAGAIV ISDMLYSRFS APKHRLLEFV RKLSGNDHII 150
    YDRVVANSEM DHSDRNASIA YLMRSFGNFD NEVMPVLKNY FHACALSMNC 200
    VDLARTFGYL ANKGIQPGIS EPIVTPMQCK QINALMATCG LYDGAGEFAY 250
    RVGMPGKSGV GGGIIAIVPG EMTIAVWSPE LDPSGNSLAG TKALELLSER 300
    IGRSIF 306
    Length:306
    Mass (Da):33,314
    Last modified:March 15, 2005 - v1
    Checksum:i1DB15690D11AA3A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000020 Genomic DNA. Translation: AAW84918.1.
    RefSeqiYP_203806.1. NC_006840.2.

    Genome annotation databases

    EnsemblBacteriaiAAW84918; AAW84918; VF_0423.
    GeneIDi3278193.
    KEGGivfi:VF_0423.
    PATRICi20111352. VBIVibFis127983_0413.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000020 Genomic DNA. Translation: AAW84918.1 .
    RefSeqi YP_203806.1. NC_006840.2.

    3D structure databases

    ProteinModelPortali Q5E7S8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 312309.VF_0423.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW84918 ; AAW84918 ; VF_0423 .
    GeneIDi 3278193.
    KEGGi vfi:VF_0423.
    PATRICi 20111352. VBIVibFis127983_0413.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi MSIAVWS.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci AFIS312309:GIWP-440-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700601 / ES114.

    Entry informationi

    Entry nameiGLSA_VIBF1
    AccessioniPrimary (citable) accession number: Q5E7S8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: March 15, 2005
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3