Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5E7L5

- IF2_VIBF1

UniProt

Q5E7L5 - IF2_VIBF1

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Vibrio fischeri (strain ATCC 700601 / ES114)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (15 Mar 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi401 – 4088GTPUniRule annotation
    Nucleotide bindingi447 – 4515GTPUniRule annotation
    Nucleotide bindingi501 – 5044GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAFIS312309:GIWP-503-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:VF_0486
    OrganismiVibrio fischeri (strain ATCC 700601 / ES114)
    Taxonomic identifieri312309 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
    ProteomesiUP000000537: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 893893Translation initiation factor IF-2PRO_0000228258Add
    BLAST

    Proteomic databases

    PRIDEiQ5E7L5.

    Interactioni

    Protein-protein interaction databases

    STRINGi312309.VF_0486.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5E7L5.
    SMRiQ5E7L5. Positions 2-50.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini392 – 561170tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni401 – 4088G1By similarity
    Regioni426 – 4305G2By similarity
    Regioni447 – 4504G3By similarity
    Regioni501 – 5044G4By similarity
    Regioni537 – 5393G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000076907.
    KOiK02519.
    OMAiDNRTGGY.
    OrthoDBiEOG67HJSV.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_B. IF_2_B.
    InterProiIPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view]
    SUPFAMiSSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5E7L5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKLTVKALS EEIGTPVDRL LQQFSDAGIN KKDGDSVTES EKQSLLVHLK    50
    KEHGSVDDSA SPTRLTLQRK TRSTLSVAGS GGKSKDVQVE VRKKRTYVKA 100
    SALEEEKKAE QLKAEAEEQA KRDAEEAAVR ELEQKAQREA EEQAKREAEA 150
    EAKAKREAEE KAKRAEADKA KKEMTKKNEQ AKKEAEELKA RQELEATRKA 200
    EAEAAKLVEE ARKLAEENEA RWKEEEQKKS AAEKDADYHV TTSSHAREAE 250
    DAADRKEEQQ PRRRKKKAKP AEAAAPRGGR NQRGGRNKKA QVNKPTSMQH 300
    GFDKSATVAK QDVAIGETIV VSELASKMSV KATEVIKVMM KMGAMATINQ 350
    VIDQETAQLV AEEMGHKVIL RKENELEEAV LSDRDNSAEA EGRAPVVTIM 400
    GHVDHGKTST LDYIRRAHVA DAEAGGITQH IGAYHVETDN GMITFLDTPG 450
    HAAFTAMRAR GAQATDIVVL VVAADDGVMP QTIEAIQHAK AAGVPLIVAV 500
    NKIDKEDANP DNVKNELAQY DVIPEEWGGE NMFVHISAKQ GTNIDGLLEA 550
    ILLQSEVLEL TAVREGMASG VVVESRLDKG RGPVATVLVQ SGTLNKGDIV 600
    LCGQEYGRVR AMRDENGKEI ESAGPSIPVE ILGLSGVPAS GDEATVVRDE 650
    RKAREVANYR QGKFRDVKLA RQQKAKLENM FSNMTAGEVA ELNVVLKADV 700
    QGSVEAIADS LRKLSTDEVK VNIVGSGVGG ITETDAVLAA ASNAIILGFN 750
    VRADATARRT IENENLDLRY YSIIYQLIDE VKAAMGGMLA PEFKQEIIGL 800
    AQVRDVFKSP KLGAIAGCMV TEGTIKRSNP IRVLRDNVVI YEGELESLRR 850
    FKDDVAEVKN GYECGIGVKN YNDVRVGDQI EVFEIVEIKR TLD 893
    Length:893
    Mass (Da):97,555
    Last modified:March 15, 2005 - v1
    Checksum:i7FE41029382211C6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000020 Genomic DNA. Translation: AAW84981.1.
    RefSeqiYP_203869.1. NC_006840.2.

    Genome annotation databases

    EnsemblBacteriaiAAW84981; AAW84981; VF_0486.
    GeneIDi3278169.
    KEGGivfi:VF_0486.
    PATRICi20111482. VBIVibFis127983_0476.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000020 Genomic DNA. Translation: AAW84981.1 .
    RefSeqi YP_203869.1. NC_006840.2.

    3D structure databases

    ProteinModelPortali Q5E7L5.
    SMRi Q5E7L5. Positions 2-50.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 312309.VF_0486.

    Proteomic databases

    PRIDEi Q5E7L5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW84981 ; AAW84981 ; VF_0486 .
    GeneIDi 3278169.
    KEGGi vfi:VF_0486.
    PATRICi 20111482. VBIVibFis127983_0476.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000076907.
    KOi K02519.
    OMAi DNRTGGY.
    OrthoDBi EOG67HJSV.

    Enzyme and pathway databases

    BioCyci AFIS312309:GIWP-503-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_B. IF_2_B.
    InterProi IPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700601 / ES114.

    Entry informationi

    Entry nameiIF2_VIBF1
    AccessioniPrimary (citable) accession number: Q5E7L5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 21, 2006
    Last sequence update: March 15, 2005
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3