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Q5E6X8 (RLMG_VIBF1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174
Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG
Gene names
Name:rlmG
Ordered Locus Names:VF_0723
OrganismVibrio fischeri (strain ATCC 700601 / ES114)
Taxonomic identifier312309 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859

Catalytic activity

S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859

Subcellular location

Cytoplasm Potential HAMAP MF_01859.

Sequence similarities

Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionrRNA (guanine-N2-)-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 382382Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859
PRO_0000366532

Sequences

Sequence LengthMass (Da)Tools
Q5E6X8 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 53EF7373E34B5DF6

FASTA38243,458
        10         20         30         40         50         60 
MKTELSLLDR SLNLQRYPKR AQELLQAWDA GDEYIIKYVE EELNLEDGKN ILILNDNFGA 

        70         80         90        100        110        120 
LSCWFSDKHN VTMMTDSFVS QRGTLKNLQR NQCNRVQLIT STEEMPQGFD LVLMQIPKNN 

       130        140        150        160        170        180 
RMLTWQLQQL RQSMDSSCPI IAVNKAKEIH SSTLELFEDY LGETKTSLAW KKHRLVFSNA 

       190        200        210        220        230        240 
NVSNPKTIAE AVCWSVDNED IDLLNYPNVY SGEKLDQGAR FMLDHIPSDP ELRHIIDLGC 

       250        260        270        280        290        300 
GNGVLSVKAG QLNPEARITC VDESFMAVES AHRNLEVNLG KERQFQFIAN NCLDGFKKHS 

       310        320        330        340        350        360 
SYLVLCNPPF HQGQAITDHI AWQMFCDAKH ILCKDGKLLV IGNRHLDYDG KLCRLFGEEN 

       370        380 
VTTVASNSKF VILEAVKAEK SK

« Hide

References

[1]"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners."
Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P.
Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005) [PubMed: 15703294] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700601 / ES114.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000020 Genomic DNA. Translation: AAW85218.1.
RefSeqYP_204106.1. NC_006840.2.

3D structure databases

ProteinModelPortalQ5E6X8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5E6X8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3277945.
GenomeReviewsGene locus VF_0723 in contig CP000020_GR.
KEGGvfi:VF_0723.
NMPDRfig|312309.3.peg.1224.
PATRIC20111992. VBIVibFis127983_0717.

Phylogenomic databases

eggNOGCOG2813.
HOGENOMHBG321931.
OMANRHLGYH.
PhylomeDBQ5E6X8.
ProtClustDBCLSK874746.

Enzyme and pathway databases

BioCycVFIS312309:VF0723-MONOMER.

Family and domain databases

HAMAPMF_01859. 23SrRNA_methyltr_G.
[Tree]
InterProIPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR007848. Small_mtfrase.
[Graphical view]
KOK11391.
PfamPF05175. MTS. 1 hit.
[Graphical view]
PIRSFPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRLMG_VIBF1
AccessionPrimary (citable) accession number: Q5E6X8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: March 15, 2005
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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