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Q5E6W6

- Q5E6W6_VIBF1

UniProt

Q5E6W6 - Q5E6W6_VIBF1

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Protein

Alanine racemase

Gene

VF_0735

Organism
Vibrio fischeri (strain ATCC 700601 / ES114)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei71 – 711Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei170 – 1701SubstrateUniRule annotation
Active sitei296 – 2961Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei344 – 3441Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAFIS312309:GIWP-770-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:VF_0735Imported
OrganismiVibrio fischeri (strain ATCC 700601 / ES114)Imported
Taxonomic identifieri312309 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
ProteomesiUP000000537: Chromosome I

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei71 – 711N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi312309.VF_0735.

Structurei

3D structure databases

ProteinModelPortaliQ5E6W6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000279190.
KOiK01775.
OMAiQQIPCVA.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5E6W6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKFTKCALAL SLALPSIANS APLLSLDTLT NQEKIQQTNA WLEIDTQAFQ
60 70 80 90 100
NNIDTLRASL EQDTKVCAIM KADAYGNGIE GLMASVIERN VECIGITSNE
110 120 130 140 150
EARIVRAKGF VGELMRVRAA SPNEIESGLQ YKIEELIGSS EQANIIAKLA
160 170 180 190 200
KQNNTIIPVH LALNAGGMGR NGLDLSQPQG KKEALNIAFN GHVNIVGIMT
210 220 230 240 250
HFPNESVDEI RTKLNLFKQE SQWLIDEAQL NRDDITLHVA NSYTTINLPE
260 270 280 290 300
AHLDMVRPGG LLYGDMPNNP EYKRIVQFKT SVASLNYLPK GSTIGYSSTY
310 320 330 340 350
VLGRDSILAN LPLGYSDGYV RSIGNNGYVL INGQKANVVG VTSMNTTMVD
360 370 380 390 400
ITDIKNVQPG DEVVLFGKQN EFTIEAKEME AFSSRSMPEL YVIWGSTNPK

IYK
Length:403
Mass (Da):44,248
Last modified:March 15, 2005 - v1
Checksum:iDD94B7C66EAD39D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000020 Genomic DNA. Translation: AAW85230.1.
RefSeqiWP_011261446.1. NC_006840.2.
YP_204118.1. NC_006840.2.

Genome annotation databases

EnsemblBacteriaiAAW85230; AAW85230; VF_0735.
GeneIDi3277953.
KEGGivfi:VF_0735.
PATRICi20112014. VBIVibFis127983_0728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000020 Genomic DNA. Translation: AAW85230.1 .
RefSeqi WP_011261446.1. NC_006840.2.
YP_204118.1. NC_006840.2.

3D structure databases

ProteinModelPortali Q5E6W6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 312309.VF_0735.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAW85230 ; AAW85230 ; VF_0735 .
GeneIDi 3277953.
KEGGi vfi:VF_0735.
PATRICi 20112014. VBIVibFis127983_0728.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000279190.
KOi K01775.
OMAi QQIPCVA.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci AFIS312309:GIWP-770-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700601 / ES114Imported.

Entry informationi

Entry nameiQ5E6W6_VIBF1
AccessioniPrimary (citable) accession number: Q5E6W6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: November 26, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3