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Q5E6W6

- Q5E6W6_VIBF1

UniProt

Q5E6W6 - Q5E6W6_VIBF1

Protein

Alanine racemase

Gene

VF_0735

Organism
Vibrio fischeri (strain ATCC 700601 / ES114)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (15 Mar 2005)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei71 – 711Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei170 – 1701SubstrateUniRule annotation
    Active sitei296 – 2961Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei344 – 3441Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciAFIS312309:GIWP-770-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:VF_0735Imported
    OrganismiVibrio fischeri (strain ATCC 700601 / ES114)Imported
    Taxonomic identifieri312309 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
    ProteomesiUP000000537: Chromosome I

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei71 – 711N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi312309.VF_0735.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5E6W6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000279190.
    KOiK01775.
    OMAiQQIPCVA.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5E6W6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFTKCALAL SLALPSIANS APLLSLDTLT NQEKIQQTNA WLEIDTQAFQ    50
    NNIDTLRASL EQDTKVCAIM KADAYGNGIE GLMASVIERN VECIGITSNE 100
    EARIVRAKGF VGELMRVRAA SPNEIESGLQ YKIEELIGSS EQANIIAKLA 150
    KQNNTIIPVH LALNAGGMGR NGLDLSQPQG KKEALNIAFN GHVNIVGIMT 200
    HFPNESVDEI RTKLNLFKQE SQWLIDEAQL NRDDITLHVA NSYTTINLPE 250
    AHLDMVRPGG LLYGDMPNNP EYKRIVQFKT SVASLNYLPK GSTIGYSSTY 300
    VLGRDSILAN LPLGYSDGYV RSIGNNGYVL INGQKANVVG VTSMNTTMVD 350
    ITDIKNVQPG DEVVLFGKQN EFTIEAKEME AFSSRSMPEL YVIWGSTNPK 400
    IYK 403
    Length:403
    Mass (Da):44,248
    Last modified:March 15, 2005 - v1
    Checksum:iDD94B7C66EAD39D7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000020 Genomic DNA. Translation: AAW85230.1.
    RefSeqiWP_011261446.1. NC_006840.2.
    YP_204118.1. NC_006840.2.

    Genome annotation databases

    EnsemblBacteriaiAAW85230; AAW85230; VF_0735.
    GeneIDi3277953.
    KEGGivfi:VF_0735.
    PATRICi20112014. VBIVibFis127983_0728.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000020 Genomic DNA. Translation: AAW85230.1 .
    RefSeqi WP_011261446.1. NC_006840.2.
    YP_204118.1. NC_006840.2.

    3D structure databases

    ProteinModelPortali Q5E6W6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 312309.VF_0735.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW85230 ; AAW85230 ; VF_0735 .
    GeneIDi 3277953.
    KEGGi vfi:VF_0735.
    PATRICi 20112014. VBIVibFis127983_0728.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000279190.
    KOi K01775.
    OMAi QQIPCVA.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci AFIS312309:GIWP-770-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700601 / ES114Imported.

    Entry informationi

    Entry nameiQ5E6W6_VIBF1
    AccessioniPrimary (citable) accession number: Q5E6W6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 15, 2005
    Last sequence update: March 15, 2005
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3