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Q5E6W6 (Q5E6W6_VIBF1) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:VF_0735 EMBL AAW85230.1
OrganismVibrio fischeri (strain ATCC 700601 / ES114) [Reference proteome] [HAMAP] EMBL AAW85230.1
Taxonomic identifier312309 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio

Protein attributes

Sequence length403 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site711Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2961Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1701Substrate By similarity HAMAP-Rule MF_01201
Binding site3441Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue711N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q5E6W6 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: DD94B7C66EAD39D7

FASTA40344,248
        10         20         30         40         50         60 
MKFTKCALAL SLALPSIANS APLLSLDTLT NQEKIQQTNA WLEIDTQAFQ NNIDTLRASL 

        70         80         90        100        110        120 
EQDTKVCAIM KADAYGNGIE GLMASVIERN VECIGITSNE EARIVRAKGF VGELMRVRAA 

       130        140        150        160        170        180 
SPNEIESGLQ YKIEELIGSS EQANIIAKLA KQNNTIIPVH LALNAGGMGR NGLDLSQPQG 

       190        200        210        220        230        240 
KKEALNIAFN GHVNIVGIMT HFPNESVDEI RTKLNLFKQE SQWLIDEAQL NRDDITLHVA 

       250        260        270        280        290        300 
NSYTTINLPE AHLDMVRPGG LLYGDMPNNP EYKRIVQFKT SVASLNYLPK GSTIGYSSTY 

       310        320        330        340        350        360 
VLGRDSILAN LPLGYSDGYV RSIGNNGYVL INGQKANVVG VTSMNTTMVD ITDIKNVQPG 

       370        380        390        400 
DEVVLFGKQN EFTIEAKEME AFSSRSMPEL YVIWGSTNPK IYK 

« Hide

References

[1]"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners."
Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P.
Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700601 / ES114.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000020 Genomic DNA. Translation: AAW85230.1.
RefSeqYP_204118.1. NC_006840.2.

3D structure databases

ProteinModelPortalQ5E6W6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING312309.VF_0735.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW85230; AAW85230; VF_0735.
GeneID3277953.
KEGGvfi:VF_0735.
PATRIC20112014. VBIVibFis127983_0728.

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000279190.
KOK01775.
OMAQQIPCVA.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycAFIS312309:GIWP-770-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5E6W6_VIBF1
AccessionPrimary (citable) accession number: Q5E6W6
Entry history
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: July 9, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)