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Q5E6W6

- Q5E6W6_VIBF1

UniProt

Q5E6W6 - Q5E6W6_VIBF1

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Protein

Alanine racemase

Gene
VF_0735
Organism
Vibrio fischeri (strain ATCC 700601 / ES114)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei71 – 711Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei170 – 1701Substrate By similarityUniRule annotation
Active sitei296 – 2961Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei344 – 3441Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAFIS312309:GIWP-770-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:VF_0735Imported
OrganismiVibrio fischeri (strain ATCC 700601 / ES114)Imported
Taxonomic identifieri312309 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
ProteomesiUP000000537: Chromosome I

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei71 – 711N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi312309.VF_0735.

Structurei

3D structure databases

ProteinModelPortaliQ5E6W6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000279190.
KOiK01775.
OMAiQQIPCVA.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5E6W6-1 [UniParc]FASTAAdd to Basket

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MKFTKCALAL SLALPSIANS APLLSLDTLT NQEKIQQTNA WLEIDTQAFQ    50
NNIDTLRASL EQDTKVCAIM KADAYGNGIE GLMASVIERN VECIGITSNE 100
EARIVRAKGF VGELMRVRAA SPNEIESGLQ YKIEELIGSS EQANIIAKLA 150
KQNNTIIPVH LALNAGGMGR NGLDLSQPQG KKEALNIAFN GHVNIVGIMT 200
HFPNESVDEI RTKLNLFKQE SQWLIDEAQL NRDDITLHVA NSYTTINLPE 250
AHLDMVRPGG LLYGDMPNNP EYKRIVQFKT SVASLNYLPK GSTIGYSSTY 300
VLGRDSILAN LPLGYSDGYV RSIGNNGYVL INGQKANVVG VTSMNTTMVD 350
ITDIKNVQPG DEVVLFGKQN EFTIEAKEME AFSSRSMPEL YVIWGSTNPK 400
IYK 403
Length:403
Mass (Da):44,248
Last modified:March 15, 2005 - v1
Checksum:iDD94B7C66EAD39D7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000020 Genomic DNA. Translation: AAW85230.1.
RefSeqiWP_011261446.1. NC_006840.2.
YP_204118.1. NC_006840.2.

Genome annotation databases

EnsemblBacteriaiAAW85230; AAW85230; VF_0735.
GeneIDi3277953.
KEGGivfi:VF_0735.
PATRICi20112014. VBIVibFis127983_0728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000020 Genomic DNA. Translation: AAW85230.1 .
RefSeqi WP_011261446.1. NC_006840.2.
YP_204118.1. NC_006840.2.

3D structure databases

ProteinModelPortali Q5E6W6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 312309.VF_0735.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAW85230 ; AAW85230 ; VF_0735 .
GeneIDi 3277953.
KEGGi vfi:VF_0735.
PATRICi 20112014. VBIVibFis127983_0728.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000279190.
KOi K01775.
OMAi QQIPCVA.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci AFIS312309:GIWP-770-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700601 / ES114.

Entry informationi

Entry nameiQ5E6W6_VIBF1
AccessioniPrimary (citable) accession number: Q5E6W6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 15, 2005
Last sequence update: March 15, 2005
Last modified: September 3, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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