Reviewed, UniProtKB/Swiss-Prot Q5E6L4 (ACKA1_VIBF1)

Names and origin

Protein names

Recommended name:
    Acetate kinase 1
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 1

Gene names

Name:	ackA1
Ordered Locus Names:	VF_0837

Organism

Vibrio fischeri (strain ATCC 700601 / ES114) [Complete proteome] [HAMAP]

Taxonomic identifier

312309 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 398	398	Acetate kinase 1 HAMAP MF_00020		PRO_0000107637

Sequences

	Sequence		Length	Mass (Da)
	Q5E6L4-1 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 97632DCDD786CD52	FASTA	398	42,661
	10 20 30 40 50 60 MSKLVLVLNC GSSSLKFAVV DAESGAEHLT GLAECLGLPE ARMKWKLDGK HEAQLGAGAA 70 80 90 100 110 120 HVEALSFMVE TILASKPELK ANLGAIGHRI VHGGEQFTKS ALITDEVLKG IQDAATFAPL 130 140 150 160 170 180 HNPAHIIGIE AAKANFPGLK NVAVFDTAFH QTMPEESYLY ALPYNLYKEH GIRRYGMHGT 190 200 210 220 230 240 SHLFITREVA GLLNKPVEEV NIINCHLGNG ASVCAIKNGE SVDTSMGLTP LEGLVMGTRC 250 260 270 280 290 300 GDIDPAIVFH LHDALGYSVE QINNMLTKES GLQGLTQVTS DCRFVEDNYG EKEEATRAMD 310 320 330 340 350 360 VFCHRLAKYV AGYTATLEGR LDAITFTGGI GENSAPIREM VLNRLGIFGI EVDGEANLKA 370 380 390 RFGGEGTITT ANSRIPAMVI STNEELVIAE DTAKLAGL

References

[1]

"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners." Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P. Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005) [PubMed: 15703294] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000020 Genomic DNA. Translation: AAW85332.1.
RefSeq	YP_204220.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5E6L4.
Genome annotation databases
GeneID	3278383.
GenomeReviews	Gene locus VF_0837 in contig CP000020_GR.
KEGG	vfi:VF_0837.
NMPDR	fig|312309.3.peg.649.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5E6L4.
OMA	PHLKDKN.
Enzyme and pathway databases
BioCyc	VFIS312309:VF0837-MON.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA1_VIBF1

Accession

Primary (citable) accession number: Q5E6L4

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2005
Last sequence update:	March 15, 2005
Last modified:	November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)