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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Vibrio fischeri (strain ATCC 700601 / ES114)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei81 – 811NucleophileUniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: UniProtKB-HAMAP
  2. RNA binding Source: InterPro

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciAFIS312309:GIWP-2183-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:VF_2071
OrganismiVibrio fischeri (strain ATCC 700601 / ES114)
Taxonomic identifieri312309 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
ProteomesiUP000000537: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351tRNA pseudouridine synthase DPRO_0000152526Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi312309.VF_2071.

Structurei

3D structure databases

ProteinModelPortaliQ5E330.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini158 – 304147TRUDUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation
Contains 1 TRUD domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0585.
HOGENOMiHOG000224848.
KOiK06176.
OMAiLWLWVEK.
OrthoDBiEOG6FRCSP.

Family and domain databases

HAMAPiMF_01082. TruD.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5E330-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDIMSNFSW LYGKPVATGK LKQLPEHFIV KEILGFEFTG NGEHLMVKIR
60 70 80 90 100
KTGENTKYVA NELAKFCGVK SKNVSWAGLK DRHAVTEQWL SVQVANSDEL
110 120 130 140 150
NFAKFEATHP GVEILEVTRH NKKLRPGDLQ GNQFQVIATE VTDIDDVLAR
160 170 180 190 200
LEKVKLAGVP NYFGSQRFGH EGNNVNEARR WGRDNVRTRD NSKRSFYLSA
210 220 230 240 250
ARSWIFNHIV SQRITEGYFS QPVDGDILLD RNDRIVNENV TSEESIQKIQ
260 270 280 290 300
NGELSITAAL AGDNQLPTTG TALTLEQPHL DAEPDLMALI RGNRMRHERR
310 320 330 340 350
AIELHPENLT WSAEGDTLTL NFSLTSGSFA TVIVRELLQE IEVERTYSSN

D
Length:351
Mass (Da):39,609
Last modified:March 15, 2005 - v1
Checksum:iA84C37A4A2C98745
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000020 Genomic DNA. Translation: AAW86566.1.
RefSeqiYP_205454.1. NC_006840.2.

Genome annotation databases

EnsemblBacteriaiAAW86566; AAW86566; VF_2071.
GeneIDi3279153.
KEGGivfi:VF_2071.
PATRICi20114866. VBIVibFis127983_2114.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000020 Genomic DNA. Translation: AAW86566.1.
RefSeqiYP_205454.1. NC_006840.2.

3D structure databases

ProteinModelPortaliQ5E330.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi312309.VF_2071.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW86566; AAW86566; VF_2071.
GeneIDi3279153.
KEGGivfi:VF_2071.
PATRICi20114866. VBIVibFis127983_2114.

Phylogenomic databases

eggNOGiCOG0585.
HOGENOMiHOG000224848.
KOiK06176.
OMAiLWLWVEK.
OrthoDBiEOG6FRCSP.

Enzyme and pathway databases

BioCyciAFIS312309:GIWP-2183-MONOMER.

Family and domain databases

HAMAPiMF_01082. TruD.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700601 / ES114.

Entry informationi

Entry nameiTRUD_VIBF1
AccessioniPrimary (citable) accession number: Q5E330
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 15, 2005
Last modified: January 7, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.