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Q5E330 (TRUD_VIBF1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase D

EC=5.4.99.27
Alternative name(s):
tRNA pseudouridine(13) synthase
tRNA pseudouridylate synthase D
tRNA-uridine isomerase D
Gene names
Name:truD
Ordered Locus Names:VF_2071
OrganismVibrio fischeri (strain ATCC 700601 / ES114) [Reference proteome] [HAMAP]
Taxonomic identifier312309 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio

Protein attributes

Sequence length351 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs By similarity. HAMAP-Rule MF_01082

Catalytic activity

tRNA uridine13 = tRNA pseudouridine13. HAMAP-Rule MF_01082

Sequence similarities

Belongs to the pseudouridine synthase TruD family.

Contains 1 TRUD domain.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 351351tRNA pseudouridine synthase D HAMAP-Rule MF_01082
PRO_0000152526

Regions

Domain158 – 304147TRUD

Sites

Active site811Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5E330 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: A84C37A4A2C98745

FASTA35139,609
        10         20         30         40         50         60 
MSDIMSNFSW LYGKPVATGK LKQLPEHFIV KEILGFEFTG NGEHLMVKIR KTGENTKYVA 

        70         80         90        100        110        120 
NELAKFCGVK SKNVSWAGLK DRHAVTEQWL SVQVANSDEL NFAKFEATHP GVEILEVTRH 

       130        140        150        160        170        180 
NKKLRPGDLQ GNQFQVIATE VTDIDDVLAR LEKVKLAGVP NYFGSQRFGH EGNNVNEARR 

       190        200        210        220        230        240 
WGRDNVRTRD NSKRSFYLSA ARSWIFNHIV SQRITEGYFS QPVDGDILLD RNDRIVNENV 

       250        260        270        280        290        300 
TSEESIQKIQ NGELSITAAL AGDNQLPTTG TALTLEQPHL DAEPDLMALI RGNRMRHERR 

       310        320        330        340        350 
AIELHPENLT WSAEGDTLTL NFSLTSGSFA TVIVRELLQE IEVERTYSSN D 

« Hide

References

[1]"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners."
Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P.
Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700601 / ES114.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000020 Genomic DNA. Translation: AAW86566.1.
RefSeqYP_205454.1. NC_006840.2.

3D structure databases

ProteinModelPortalQ5E330.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING312309.VF_2071.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW86566; AAW86566; VF_2071.
GeneID3279153.
KEGGvfi:VF_2071.
PATRIC20114866. VBIVibFis127983_2114.

Phylogenomic databases

eggNOGCOG0585.
HOGENOMHOG000224848.
KOK06176.
OMAALTRQWF.
OrthoDBEOG6FRCSP.

Enzyme and pathway databases

BioCycAFIS312309:GIWP-2183-MONOMER.

Family and domain databases

HAMAPMF_01082. TruD.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERPTHR13326. PTHR13326. 1 hit.
PfamPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
PROSITEPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRUD_VIBF1
AccessionPrimary (citable) accession number: Q5E330
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 15, 2005
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families