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Protein

Purine nucleoside phosphorylase DeoD-type 2

Gene

deoD2

Organism
Vibrio fischeri (strain ATCC 700601 / ES114)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.UniRule annotation
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei5Purine nucleoside; shared with dimeric partnerBy similarity1
Binding sitei21Phosphate; via amide nitrogenBy similarity1
Binding sitei25PhosphateBy similarity1
Binding sitei44Phosphate; shared with dimeric partnerBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylase DeoD-type 2UniRule annotation (EC:2.4.2.1UniRule annotation)
Short name:
PNP 2UniRule annotation
Gene namesi
Name:deoD2UniRule annotation
Ordered Locus Names:VF_A0402
OrganismiVibrio fischeri (strain ATCC 700601 / ES114)
Taxonomic identifieri312309 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
Proteomesi
  • UP000000537 Componenti: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000631721 – 236Purine nucleoside phosphorylase DeoD-type 2Add BLAST236

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi312309.VF_A0402.

Structurei

3D structure databases

ProteinModelPortaliQ5E0H4.
SMRiQ5E0H4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni88 – 91Phosphate bindingBy similarity4
Regioni180 – 182Purine nucleoside bindingBy similarity3
Regioni204 – 205Purine nucleoside bindingBy similarity2

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D3A. Bacteria.
COG0813. LUCA.
HOGENOMiHOG000274896.
KOiK03784.
OMAiQYNSIRN.
OrthoDBiPOG091H02M1.

Family and domain databases

HAMAPiMF_01627. Pur_nucleosid_phosp. 1 hit.
InterProiView protein in InterPro
IPR004402. DeoD-type.
IPR000845. Nucleoside_phosphorylase_d.
PANTHERiPTHR43691:SF1. PTHR43691:SF1. 1 hit.
PfamiView protein in Pfam
PF01048. PNP_UDP_1. 1 hit.
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5E0H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPHINAQA GDFAETVLMP GDPLRAKFIA ENFLEDVKQV CDVRNMFGYT
60 70 80 90 100
GTYKGKKVSV MGHGMGIPSC CIYVHELIAE YGVKNVIRVG SCGAVHDDVK
110 120 130 140 150
LMDVVIGMGA STDSKVNRIR FNNHDFAAIA DFGLLETAVG QARELNVPVK
160 170 180 190 200
VGNVFSADLF YSPEADLFDK MEKLGILGVD MEAAGIYGVA ADLGAKALTI
210 220 230
LTVSDHIKRG EKLSSEDRQK SFNDMMTVAL ETAIKL
Length:236
Mass (Da):25,511
Last modified:March 15, 2005 - v1
Checksum:iF0274918A6D90B2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000021 Genomic DNA. Translation: AAW87472.1.
RefSeqiWP_005422471.1. NC_006841.2.
YP_206360.1. NC_006841.2.

Genome annotation databases

EnsemblBacteriaiAAW87472; AAW87472; VF_A0402.
GeneIDi3280648.
KEGGivfi:VF_A0402.
PATRICi20116784. VBIVibFis127983_3005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000021 Genomic DNA. Translation: AAW87472.1.
RefSeqiWP_005422471.1. NC_006841.2.
YP_206360.1. NC_006841.2.

3D structure databases

ProteinModelPortaliQ5E0H4.
SMRiQ5E0H4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi312309.VF_A0402.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW87472; AAW87472; VF_A0402.
GeneIDi3280648.
KEGGivfi:VF_A0402.
PATRICi20116784. VBIVibFis127983_3005.

Phylogenomic databases

eggNOGiENOG4105D3A. Bacteria.
COG0813. LUCA.
HOGENOMiHOG000274896.
KOiK03784.
OMAiQYNSIRN.
OrthoDBiPOG091H02M1.

Family and domain databases

HAMAPiMF_01627. Pur_nucleosid_phosp. 1 hit.
InterProiView protein in InterPro
IPR004402. DeoD-type.
IPR000845. Nucleoside_phosphorylase_d.
PANTHERiPTHR43691:SF1. PTHR43691:SF1. 1 hit.
PfamiView protein in Pfam
PF01048. PNP_UDP_1. 1 hit.
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDEOD2_VIBF1
AccessioniPrimary (citable) accession number: Q5E0H4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 15, 2005
Last modified: May 10, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.