Q5DZD2 (ACKA2_VIBF1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase 2
EC=2.7.2.1

Alternative name(s):
Acetokinase 2

Gene names

Name:	ackA2
Ordered Locus Names:	VF_A0794

Organism

Vibrio fischeri (strain ATCC 700601 / ES114)

Taxonomic identifier

312309 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.
Sequence caution	The sequence AAW87864.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase 2 HAMAP MF_00020		PRO_0000107638

Sequences

	Sequence		Length	Mass (Da)
	Q5DZD2 [UniParc]. Last modified August 2, 2005. Version 2. Checksum: C10F689FF0FB3FC4	FASTA	397	42,742
	10 20 30 40 50 60 MNNEYVLVIN SGSSSLKFAV IDSVSGDAVL SGLGECFGLE DARMSWKYQG QKTEIAIEGN 70 80 90 100 110 120 ENHHKIAIGK LVGLTEELGF TDGIVAIGHR IVHGGEKFTK TVRINEEVTK EIESLSDLAP 130 140 150 160 170 180 LHNPAGAIGI RAAVEAFPSL PQFAVFDTAF HQTMPKRAYT GAIAKELYTD FGVRRYGFHG 190 200 210 220 230 240 TSHYFVSREA AKMINKPIEE SNFISVHLGN GASVCAIKDG NSVDTSMGFT PLSGLMMGTR 250 260 270 280 290 300 CGDLDPGIIE YLLKKGWSQE QVFNSLNKES GFLGVSGLTS DARGILEAME EGHEGATLAF 310 320 330 340 350 360 QVFTYRVAKY VASYLAALDS LDGIIFTGGI GENSLPIRRE ILSNLKILGF VEDVAGNEGA 370 380 390 RFGADGIIAK SEMLNAVAMV IPTNEEFVIA QQSVELL

References

[1]

"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners." Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P. Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005) [PubMed: 15703294] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700601 / ES114.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000021 Genomic DNA. Translation: AAW87864.1. Different initiation.
RefSeq	YP_206752.1. NC_006841.2.
3D structure databases
ProteinModelPortal	Q5DZD2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5DZD2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3280580.
GenomeReviews	Gene locus VF_A0794 in contig CP000021_GR.
KEGG	vfi:VF_A0794.
NMPDR	fig|312309.3.peg.3711.
PATRIC	20117585. VBIVibFis127983_3396.
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	AMEEGHE.
PhylomeDB	Q5DZD2.
ProtClustDB	PRK12440.
Enzyme and pathway databases
BioCyc	VFIS312309:VFA0794-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA2_VIBF1

Accession

Primary (citable) accession number: Q5DZD2

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2005
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 50 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program