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Q5DUX5 (NDUS2_NYCOV) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH-ubiquinone oxidoreductase 49 kDa subunit

EC=1.6.5.3
EC=1.6.99.3
Alternative name(s):
NADH dehydrogenase subunit 7
Gene names
Name:nad7
Encoded onHydrogenosome
OrganismNyctotherus ovalis
Taxonomic identifier70075 [NCBI]
Taxonomic lineageEukaryotaAlveolataCiliophoraIntramacronucleataArmophoreaArmophoridaMetopidaeNyctotherus

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Component of the iron-sulfur (IP) fragment of the enzyme.

Catalytic activity

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).

NADH + acceptor = NAD+ + reduced acceptor.

Subcellular location

Hydrogenosome.

Sequence similarities

Belongs to the complex I 49 kDa subunit family.

Ontologies

Keywords
   Cellular componentHydrogenosome
   LigandNAD
Ubiquinone
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Cellular_componenthydrogenosome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionNAD binding

Inferred from electronic annotation. Source: InterPro

NADH dehydrogenase (ubiquinone) activity

Inferred from electronic annotation. Source: UniProtKB-EC

quinone binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 412412NADH-ubiquinone oxidoreductase 49 kDa subunit
PRO_0000118595

Sequences

Sequence LengthMass (Da)Tools
Q5DUX5 [UniParc].

Last modified March 29, 2005. Version 1.
Checksum: 2760DF6EB2DB6E89

FASTA41246,974
        10         20         30         40         50         60 
MMRSSSLQKN IMLLRVGSKD STRFRILILN FGPQHPASHG VLRLVIVIIG EVVTKLDPHI 

        70         80         90        100        110        120 
GFLHRGTERL VEEHSYMNAA VFMDRLDYTT VLTQTHAYCL AVEQALAKSR LCIRTQLLRT 

       130        140        150        160        170        180 
IFDELSRILN HLLSIATHAL DIGTMAMLFW AFEDRERIME LYEYISGARM HTALYYPNQT 

       190        200        210        220        230        240 
LDHILTNELL AKILIFSRNS EKTYTEIYIA LYNNRVWRLR LCGIGVVSTE ISTSTTISGP 

       250        260        270        280        290        300 
VARSTGLQLD MRSGENYQYG YYASLTLRIF LGISGDSFDR FIIRLRELFE STRLIYNSLI 

       310        320        330        340        350        360 
ELSAYINISV YNMCSYSNNP HLKIESLIEL FRYSLGEYLL NISLVSGFVE SGKGIFGIML 

       370        380        390        400        410 
AANNTNRPYR LYIRSPAYMH LQLLPKLGAG HHIADLATLL GSIDVVFGEV DR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ871267 Genomic DNA. Translation: CAI38863.1.

3D structure databases

ProteinModelPortalQ5DUX5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.645.10. 1 hit.
InterProIPR001135. NADH_Q_OxRdtase_suD.
IPR029014. NiFe_Hase-like.
[Graphical view]
PfamPF00346. Complex1_49kDa. 1 hit.
[Graphical view]
SUPFAMSSF56762. SSF56762. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNDUS2_NYCOV
AccessionPrimary (citable) accession number: Q5DUX5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2005
Last sequence update: March 29, 2005
Last modified: June 11, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families