Pak2

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: InterPro
protein serine/threonine kinase activity Source: InterPro

GO - Biological processⁱ

regulation of apoptotic process Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MKIAA4182 proteinImported
Gene namesⁱ	Name:Pak2Imported Synonyms:mKIAA4182Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:1339984. Pak2.

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q5DTJ2.
PeptideAtlas More...PeptideAtlasⁱ	Q5DTJ2.
PRIDEⁱ	Q5DTJ2.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000022781.

Bgeeⁱ

ENSMUSG00000022781.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5DTJ2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 201	Protein kinaseInterPro annotationAdd BLAST		201

Phylogenomic databases

eggNOGⁱ	KOG0578. Eukaryota. ENOG410XP4K. LUCA.
HOVERGENⁱ	HBG108518.
KEGG Orthology (KO) More...KOⁱ	K04410.

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009. Kinase-like_dom. IPR035065. PAK2. IPR000719. Prot_kinase_dom. IPR008271. Ser/Thr_kinase_AS.
PANTHERⁱ	PTHR24361:SF592. PTHR24361:SF592. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069. Pkinase. 1 hit.
SMARTⁱ	View protein in SMART SM00220. S_TKc. 1 hit.
SUPFAMⁱ	SSF56112. SSF56112. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q5DTJ2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
ELKNPNIVNF LDSYLVGDEL FVVMEYLAGG SLTDVVTETC MDEAQIAAVC 
        60         70         80         90        100
RECLQALEFL HANQVIHRDI KSDNVLLGME GSVKLTDFGF CAQITPEQSK 
       110        120        130        140        150
RSTMVGTPYW MAPEVVTRKA YGPKVDIWSL GIMAIEMVEG EPPYLNENPL 
       160        170        180        190        200
RALYLIATNG TPELQNPEKL SPIFRDFLNR CLEMDVEKRG SAKELLQHPF 
       210        220 
LKLAKPLSSL TPLILAAKEA MKSNR

Length:225

Mass (Da):25,134

Last modified:March 29, 2005 - v1

Checksum:ⁱAD225E439372BAB5

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK220528 mRNA. Translation: BAD90309.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_796300.1. NM_177326.3.
UniGeneⁱ	Mm.234204.

Genome annotation databases

GeneIDⁱ	224105.
KEGGⁱ	mmu:224105.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK220528 mRNA. Translation: BAD90309.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_796300.1. NM_177326.3.
UniGeneⁱ	Mm.234204.

3D structure databases

ProteinModelPortalⁱ	Q5DTJ2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	Q5DTJ2.
PeptideAtlas More...PeptideAtlasⁱ	Q5DTJ2.
PRIDEⁱ	Q5DTJ2.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	224105.
KEGGⁱ	mmu:224105.

Organism-specific databases

CTDⁱ	5062.
MGIⁱ	MGI:1339984. Pak2.

Phylogenomic databases

eggNOGⁱ	KOG0578. Eukaryota. ENOG410XP4K. LUCA.
HOVERGENⁱ	HBG108518.
KEGG Orthology (KO) More...KOⁱ	K04410.

Miscellaneous databases

ChiTaRSⁱ	Pak2. mouse.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000022781.

Bgeeⁱ

ENSMUSG00000022781.

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009. Kinase-like_dom. IPR035065. PAK2. IPR000719. Prot_kinase_dom. IPR008271. Ser/Thr_kinase_AS.
PANTHERⁱ	PTHR24361:SF592. PTHR24361:SF592. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069. Pkinase. 1 hit.
SMARTⁱ	View protein in SMART SM00220. S_TKc. 1 hit.
SUPFAMⁱ	SSF56112. SSF56112. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5DTJ2_MOUSE
Accessionⁱ	Q5DTJ2Primary (citable) accession number: Q5DTJ2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 29, 2005
	Last sequence update:	March 29, 2005
	Last modified:	July 5, 2017
	This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q5DTJ2 (Q5DTJ2_MOUSE)

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MKIAA4182 protein

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5DTJ2 (Q5DTJ2_MOUSE)

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MKIAA4182 protein

Pak2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ