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Protein
Submitted name:

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, isoform CRA_b

Gene

Atp2a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, isoform CRA_bImported
Submitted name:
MKIAA4195 proteinImported
Gene namesi
Name:Atp2a2Imported
Synonyms:mKIAA4195Imported
ORF Names:mCG_12168Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88110. Atp2a2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei77 – 95HelicalSequence analysisAdd BLAST19
Transmembranei101 – 124HelicalSequence analysisAdd BLAST24
Transmembranei277 – 297HelicalSequence analysisAdd BLAST21
Transmembranei309 – 338HelicalSequence analysisAdd BLAST30
Transmembranei776 – 799HelicalSequence analysisAdd BLAST24
Transmembranei850 – 873HelicalSequence analysisAdd BLAST24
Transmembranei947 – 966HelicalSequence analysisAdd BLAST20
Transmembranei1032 – 1050HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ5DTI2.
PRIDEiQ5DTI2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000029467.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031423.

Structurei

3D structure databases

ProteinModelPortaliQ5DTI2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 94Cation_ATPase_NInterPro annotationAdd BLAST75

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0202. Eukaryota.
COG0474. LUCA.
HOGENOMiHOG000265621.
HOVERGENiHBG105648.
KOiK05853.

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR005782. P-type_ATPase_IIA.
IPR001757. P_typ_ATPase.
IPR030327. SERCA2.
[Graphical view]
PANTHERiPTHR24093:SF234. PTHR24093:SF234. 2 hits.
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF08282. Hydrolase_3. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01116. ATPase-IIA1_Ca. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5DTI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ARRPRGREAR PAGAPAAMEN AHTKTVEEVL GHFGVNESTG LSLEQVKKLK
60 70 80 90 100
ERWGSNELPA EEGKTLLELV IEQFEDLLVR ILLLAACISF VLAWFEEGEE
110 120 130 140 150
TITAFVEPFV ILLILVANAI VGVWQERNAE NAIEALKEYE PEMGKVYRQD
160 170 180 190 200
RKSVQRIKAK DIVPGDIVEI AVGDKVPADI RLTSIKSTTL RVDQSILTGE
210 220 230 240 250
SVSVIKHTDP VPDPRAVNQD KKNMLFSGTN IAAGKAMGVV VATGVNTEIG
260 270 280 290 300
KIRDEMVATE QERTPLQQKL DEFGEQLSKV ISLICIAVWI INIGHFNDPV
310 320 330 340 350
HGGSWIRGAI YYFKIAVALA VAAIPEGLPA VITTCLALGT RRMAKKNAIV
360 370 380 390 400
RSLPSVETLG CTSVICSDKT GTLTTNQMSV CRMFILDKVE GDTCSLNEFS
410 420 430 440 450
ITGSTYAPIG EVQKDDKPVK CHQYDGLVEL ATICALCNDS ALDYNEAKGV
460 470 480 490 500
YEKVGEATET ALTCLVEKMN VFDTELKGLS KIERANACNS VIKQLMKKEF
510 520 530 540 550
TLEFSRDRKS MSVYCTPNKP SRTSMSKMFV KGAPEGVIDR CTHIRVGSTK
560 570 580 590 600
VPMTPGVKQK IMSVIREWGS GSDTLRCLAL ATHDNPLKRE EMHLEDSANF
610 620 630 640 650
IKYETNLTFV GCVGMLDPPR IEVASSVKLC RQAGIRVIMI TGDNKGTAVA
660 670 680 690 700
ICRRIGIFGQ DEDVTSKAFT GREFDELSPS AQRDACLNAR CFARVEPSHK
710 720 730 740 750
SKIVEFLQSF DEITAMTGDG VNDAPALKKS EIGIAMGSGT AVAKTASEMV
760 770 780 790 800
LADDNFSTIV AAVEEGRAIY NNMKQFIRYL ISSNVGEVVC IFLTAALGFP
810 820 830 840 850
EALIPVQLLW VNLVTDGLPA TALGFNPPDL DIMNKPPRNP KEPLISGWLF
860 870 880 890 900
FRYLAIGCYV GAATVGAAAW WFIAADGGPR VSFYQLSHFL QCKEDNPDFD
910 920 930 940 950
GVDCAIFESP YPMTMALSVL VTIEMCNALN SLSENQSLLR MPPWENIWLV
960 970 980 990 1000
GSICLSMSLH FLILYVEPLP LIFQITPLNL TQWLMVLKIS LPVILMDETL
1010 1020 1030 1040 1050
KFVARNYLEQ PGKECVQPAT KSSCSLSACT DGISWPFVLL IMPLVVWVYS
1060
TDTNFSDMFW S
Length:1,061
Mass (Da):116,600
Last modified:March 29, 2005 - v1
Checksum:i36926C3C74B87480
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK220538 mRNA. Translation: BAD90532.1.
CH466529 Genomic DNA. Translation: EDL19677.1.
RefSeqiNP_001103610.1. NM_001110140.3.
NP_033852.1. NM_009722.3.
UniGeneiMm.227583.

Genome annotation databases

GeneIDi11938.
KEGGimmu:11938.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK220538 mRNA. Translation: BAD90532.1.
CH466529 Genomic DNA. Translation: EDL19677.1.
RefSeqiNP_001103610.1. NM_001110140.3.
NP_033852.1. NM_009722.3.
UniGeneiMm.227583.

3D structure databases

ProteinModelPortaliQ5DTI2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031423.

Proteomic databases

PeptideAtlasiQ5DTI2.
PRIDEiQ5DTI2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11938.
KEGGimmu:11938.

Organism-specific databases

CTDi488.
MGIiMGI:88110. Atp2a2.

Phylogenomic databases

eggNOGiKOG0202. Eukaryota.
COG0474. LUCA.
HOGENOMiHOG000265621.
HOVERGENiHBG105648.
KOiK05853.

Miscellaneous databases

ChiTaRSiAtp2a2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029467.

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR005782. P-type_ATPase_IIA.
IPR001757. P_typ_ATPase.
IPR030327. SERCA2.
[Graphical view]
PANTHERiPTHR24093:SF234. PTHR24093:SF234. 2 hits.
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF08282. Hydrolase_3. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01116. ATPase-IIA1_Ca. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5DTI2_MOUSE
AccessioniPrimary (citable) accession number: Q5DTI2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 29, 2005
Last sequence update: March 29, 2005
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.