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Protein

UDP-glucuronosyltransferase

Gene

UGT1A9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesi
Name:UGT1A9Imported
ORF Names:hCG_2039726Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000241119.1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei488 – 511HelicalUniRule annotationAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA419.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25UniRule annotationAdd BLAST25
ChainiPRO_500999873526 – 530UDP-glucuronosyltransferaseUniRule annotationAdd BLAST505

Proteomic databases

MaxQBiQ5DSZ5.

Expressioni

Gene expression databases

BgeeiENSG00000241119.
ExpressionAtlasiQ5DSZ5. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini351 – 394UDPGTInterPro annotationAdd BLAST44

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
HOVERGENiHBG004033.
KOiK00699.
OMAiMPEVSWH.
OrthoDBiEOG091G06JC.

Family and domain databases

InterProiView protein in InterPro
IPR002213. UDP_glucos_trans.
IPR035595. UDP_glycos_trans_CS.
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiView protein in Pfam
PF00201. UDPGT. 1 hit.
PROSITEiView protein in PROSITE
PS00375. UDPGT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5DSZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACTGWTSPL PLCVCLLLTC GFAEAGKLLV VPMDGSHWFT MRSVVEKLIL
60 70 80 90 100
RGHEVVVVMP EVSWQLGRSL NCTVKTYSTS YTLEDLDREF KAFAHAQWKA
110 120 130 140 150
QVRSIYSLLM GSYNDIFDLF FSNCRSLFKD KKLVEYLKES SFDAVFLDPF
160 170 180 190 200
DNCGLIVAKY FSLPSVVFAR GILCHYLEEG AQCPAPLSYV PRILLGFSDA
210 220 230 240 250
MTFKERVRNH IMHLEEHLLC HRFFKNALEI ASEILQTPVT EYDLYSHTSI
260 270 280 290 300
WLLRTDFVLD YPKPVMPNMI FIGGINCHQG KPLPMEFEAY INASGEHGIV
310 320 330 340 350
VFSLGSMVSE IPEKKAMAIA DALGKIPQTV LWRYTGTRPS NLANNTILVK
360 370 380 390 400
WLPQNDLLGH PMTRAFITHA GSHGVYESIC NGVPMVMMPL FGDQMDNAKR
410 420 430 440 450
METKGAGVTL NVLEMTSEDL ENALKAVIND KSYKENIMRL SSLHKDRPVE
460 470 480 490 500
PLDLAVFWVE FVMRHKGAPH LRPAAHDLTW YQYHSLDVIG FLLAVVLTVA
510 520 530
FITFKCCAYG YRKCLGKKGR VKKAHKSKTH
Length:530
Mass (Da):59,941
Last modified:May 10, 2005 - v1
Checksum:iC417B9E86B403078
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY435144 mRNA. Translation: AAR95645.1.
AK313510 mRNA. Translation: BAG36290.1.
CH471063 Genomic DNA. Translation: EAW71054.1.
RefSeqiNP_066307.1. NM_021027.2.
UniGeneiHs.554822.

Genome annotation databases

GeneIDi54600.
KEGGihsa:54600.
UCSCiuc002vus.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ5DSZ5_HUMAN
AccessioniPrimary (citable) accession number: Q5DSZ5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.