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Protein
Submitted name:

Reverse transcriptase

Gene

pol

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionNucleotidyltransferase, RNA-directed DNA polymeraseSAAS annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Reverse transcriptaseImported
Gene namesi
Name:polImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Structurei

3D structure databases

ProteinModelPortaliQ5DNL9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 234Reverse transcriptaseInterPro annotationAdd BLAST191
Domaini434 – 557RNase HInterPro annotationAdd BLAST124

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiView protein in InterPro
IPR012337. RNaseH-like_dom.
IPR002156. RNaseH_domain.
IPR000477. RT_dom.
IPR010659. RVT_connect.
IPR010661. RVT_thumb.
PfamiView protein in Pfam
PF00075. RNase_H. 1 hit.
PF00078. RVT_1. 1 hit.
PF06815. RVT_connect. 1 hit.
PF06817. RVT_thumb. 1 hit.
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiView protein in PROSITE
PS50879. RNASE_H. 1 hit.
PS50878. RT_POL. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5DNL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PISPIETVPV QLKPGMDGPK VKQWPLTEEK IKALVEICTE MEKEGKISKI
60 70 80 90 100
GPENPYNTPV FAIKKKDSTK WRKLVDFREL NKKTQDFWEV QLGIPHPAGL
110 120 130 140 150
KKKKSVTVLD VGDAYFSVPL DPDFRKYTAF TIPSINNETP GIRYQYNVLP
160 170 180 190 200
QGWKGSPAIF QSSMTKILEP FRKQNPEIVI YQYMDDLYVG SDLEIGQHRT
210 220 230 240 250
KIEELRQHLL RWGLTTPDKK HQKEPPFLWM GYELHPDKWA VQPIVLPEKD
260 270 280 290 300
SWTVNDIQKL VGKLNWASQI YAGIKVRELC KLLRGTKALT EVIPLTEEAE
310 320 330 340 350
LELAENREIL KEPVHGVYYD PSKDLIAEIQ KQGQGQWTYQ IYQEPFKNLK
360 370 380 390 400
TGKYARMRGA HTNDVKQLTE AVQKIAMESI VIWGKTPKFR LPIQKETWET
410 420 430 440 450
WWAEYWQATW IPEWEFVNTP PLVKLWYQLE KEPIVGAETF YVDGAANRET
460 470 480 490 500
KLGKAGYVTD KGRQKVVSLT DTTNQKTELQ AIHLALQDSG SEVNIVTDSQ
510 520 530 540 550
YALGIIQAQP DKSESELVNQ IIEQLINKEK VYLAWVPAHK GIGGNEQVDK
560
LVSTGIRKVL
Length:560
Mass (Da):64,299
Last modified:March 29, 2005 - v1
Checksum:iADF0EB05EA4B45FD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei560Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY560468 Genomic DNA. Translation: AAT66854.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ5DNL9_9HIV1
AccessioniPrimary (citable) accession number: Q5DNL9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 29, 2005
Last sequence update: March 29, 2005
Last modified: April 12, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)