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Q5D044

- Q5D044_HUMAN

UniProt

Q5D044 - Q5D044_HUMAN

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Protein
Submitted name:

LAMA4 protein

Gene

LAMA4

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cell adhesion Source: InterPro
  2. regulation of cell adhesion Source: InterPro
  3. regulation of cell migration Source: InterPro
  4. regulation of embryonic development Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
LAMA4 proteinImported
Gene namesi
Name:LAMA4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. laminin-1 complex Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30273.

PTM / Processingi

Proteomic databases

PRIDEiQ5D044.

Structurei

3D structure databases

ProteinModelPortaliQ5D044.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000113278.
HOVERGENiHBG052299.
KOiK06241.

Family and domain databases

Gene3Di2.60.120.200. 5 hits.
InterProiIPR013320. ConA-like_dom.
IPR002049. EGF_laminin.
IPR010307. Laminin_domII.
IPR001791. Laminin_G.
IPR009254. Laminin_I.
[Graphical view]
PfamiPF00053. Laminin_EGF. 3 hits.
PF02210. Laminin_G_2. 5 hits.
PF06008. Laminin_I. 1 hit.
PF06009. Laminin_II. 1 hit.
[Graphical view]
SMARTiSM00180. EGF_Lam. 3 hits.
SM00282. LamG. 5 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 5 hits.
PROSITEiPS01248. EGF_LAM_1. 3 hits.
PS50027. EGF_LAM_2. 3 hits.
PS50025. LAM_G_DOMAIN. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5D044-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALSSAWRSV LPLWLLWSAA CSRAASGDDN AFPFDIEGSS AVGRQDPPET
60 70 80 90 100
SEPRVALGRL PPAAEKCNAG FFHTLSGECV PCDCNGNSNE CLDGSGYCVH
110 120 130 140 150
CQRNTTGEHC EKCLDGYIGD SIRGAPQFCQ PCPCPLPHLA NFAESCYRKN
160 170 180 190 200
GAVRCICNEN YAGPNCERCA PGYYGNPLLI GSTCKKCDCS GNSDPNLIFE
210 220 230 240 250
DCDEVTGQCR NCLRNTTGFK CERCAPGYYG DARIAKNCAV CNCGGGPCDS
260 270 280 290 300
VTGECLEEGF EPPTGCDKCV WDLTDDLRLA ALSIEEGKSG VLSVSSGAAA
310 320 330 340 350
HRHVNEINAT IYLLKTKLSE RENQYALRKI QINNAENTMK SLLSDVEELV
360 370 380 390 400
EKENQASRKG QLVQKESMDT INHASQLVEQ AHDMRDKIQE INNKMLYYGE
410 420 430 440 450
EHELSPKEIS EKLVLAQKML EEIRSRQPFF TQRELVDEEA DEAYELLSQA
460 470 480 490 500
ESWQRLHNET RTLFPVVLEQ LDDYNAKLSD LQEALDQALN HVRDAEDMNR
510 520 530 540 550
ATAARQRDHE KQQERVREQM EVVNMSLSTS ADSLTTPRLT LSELDDIIKN
560 570 580 590 600
ASGIYAEIDG AKSELQVKLS NLSNLSHDLV QEAIDHAQDL QQEANELSRK
610 620 630 640 650
LHSSDMNGLV QKALDASNVY ENIVNYVSEA NETAEFALNT TDRIYDAVSG
660 670 680 690 700
IDTQIIYHKD ESENLLNQAR ELQAKAESSS DEAVADTSRR VGGALARKSA
710 720 730 740 750
LKTRLSDAVK QLQAAERGDA QQRLGQSRLI TEEANRTTME VQQATAPMAN
760 770 780 790 800
NLTNWSQNLQ HFDSSAYNTA VNSARDAVRN LTEVVPQLLD QLRTVEQKRP
810 820 830 840 850
ASNVSASIQR IRELIAQTRS VASKIQVSMM FDGQSAVEVH SRTSMDDLKA
860 870 880 890 900
FTSLSLYMKP PVKRPELTET ADQFILYLGS KNAKKEYMGL AIKNDNLVYV
910 920 930 940 950
YNLGTKDVEI PLDSKPVSSW PAYFSIVKIE RVGKHGKVFL TVPSLSSTAE
960 970 980 990 1000
EKFIKKGEFS GDDSLLDLDP EDTVFYVGGV PSNFKLPTSL NLPGFVGCLE
1010 1020 1030 1040 1050
LATLNNDVIS LYNFKHIYNM DPSTSVPCAR DKLAFTQSRA ASYFFDGSGY
1060 1070 1080 1090 1100
AVVRDITRRG KFGQVTRFDI EVRTPADNGL ILLMVNGSMF FRLEMRNGYL
1110 1120 1130 1140 1150
HVFYDFGFSS GRVHLEDTLK KAQINDAKYH EISIIYHNDK KMILVVDRRH
1160 1170 1180 1190 1200
VKSMDNEKMK IPFTDIYIGG APPEILQSRA LRAHLPLDIN FRGCMKGFQF
1210 1220 1230 1240 1250
QKKDFNLLEQ TETLGVGYGC PEDSLISRRA YFNGQSFIAS IQKISFFDGF
1260 1270 1280 1290 1300
EGGFNFRTLQ PNGLLFYYAS GSDVFSISLD NGTVIMDVKG IKVQSVDKQY
1310 1320 1330 1340 1350
NDGLSHFVIS SVSPTRYELI VDKSRVGSKN PTKGKIEQTQ ASEKKFYFGG
1360 1370 1380 1390 1400
SPISAQYANF TGCISNAYFT RVDRDVEVED FQRYTEKVHT SLYECPIESS
1410 1420 1430 1440 1450
PLFLLHKKGK NLSKPKASQN KKGGKSKDAP SWDPVALKLP ERNTPRNSHC
1460 1470 1480 1490 1500
HLSNSPRAIE HAYQYGGTAN SRQEFEHLKG DFGAKSQFSI RLRTRSSHGM
1510 1520 1530 1540 1550
IFYVSDQEEN DFMTLFLAHG RLVYMFNVGH KKLKIRSQEK YNDGLWHDVI
1560 1570 1580 1590 1600
FIRERSSGRL VIDGLRVLEE SLPPTEATWK IKGPIYLGGV APGKAVKNVQ
1610 1620 1630 1640 1650
INSIYSFSGC LSNLQLNGAS ITSASQTFSV TPCFEGPMET GTYFSTEGGY
1660 1670 1680 1690 1700
VVLDESFNIG LKFEIAFEVR PRSSSGTLVH GHSVNGEYLN VHMKNGQVIV
1710 1720 1730 1740 1750
KVNNGIRDFS TSVTPKQSLC DGRWHRITVI RDSNVVQLDV DSEVNHVVGP
1760 1770 1780 1790 1800
LNPKPIDHRE PVFVGGVPES LLTPRLAPSK PFTGCIRHFV IDGHPVSFSK
1810
AALVSGAVSI NSCPAA
Length:1,816
Mass (Da):201,883
Last modified:May 10, 2005 - v1
Checksum:i57235EB9AB1657CA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC066552 mRNA. Translation: AAH66552.1.
RefSeqiNP_001098677.2. NM_001105207.2.
UniGeneiHs.654572.

Genome annotation databases

GeneIDi3910.
KEGGihsa:3910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC066552 mRNA. Translation: AAH66552.1 .
RefSeqi NP_001098677.2. NM_001105207.2.
UniGenei Hs.654572.

3D structure databases

ProteinModelPortali Q5D044.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q5D044.

Protocols and materials databases

DNASUi 3910.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3910.
KEGGi hsa:3910.

Organism-specific databases

CTDi 3910.
PharmGKBi PA30273.

Phylogenomic databases

HOGENOMi HOG000113278.
HOVERGENi HBG052299.
KOi K06241.

Miscellaneous databases

ChiTaRSi LAMA4. human.
GenomeRNAii 3910.
NextBioi 15351.

Family and domain databases

Gene3Di 2.60.120.200. 5 hits.
InterProi IPR013320. ConA-like_dom.
IPR002049. EGF_laminin.
IPR010307. Laminin_domII.
IPR001791. Laminin_G.
IPR009254. Laminin_I.
[Graphical view ]
Pfami PF00053. Laminin_EGF. 3 hits.
PF02210. Laminin_G_2. 5 hits.
PF06008. Laminin_I. 1 hit.
PF06009. Laminin_II. 1 hit.
[Graphical view ]
SMARTi SM00180. EGF_Lam. 3 hits.
SM00282. LamG. 5 hits.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 5 hits.
PROSITEi PS01248. EGF_LAM_1. 3 hits.
PS50027. EGF_LAM_2. 3 hits.
PS50025. LAM_G_DOMAIN. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: SkinImported.

Entry informationi

Entry nameiQ5D044_HUMAN
AccessioniPrimary (citable) accession number: Q5D044
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.