Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q5CZY4 (Q5CZY4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Nuclear factor 1 RuleBase RU000690
Gene names
Name:Nfix EMBL AAH90626.1 MGI 97311
OrganismMus musculus (Mouse) EMBL AAH90626.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length507 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication By similarity. RuleBase RU000690

Subunit structure

Binds DNA as a homodimer By similarity. RuleBase RU000690

Subcellular location

Nucleus By similarity RuleBase RU000690.

Sequence similarities

Belongs to the CTF/NF-I family. RuleBase RU000690

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAH90626.1

Sequences

Sequence LengthMass (Da)Tools
Q5CZY4 [UniParc].

Last modified March 29, 2005. Version 1.
Checksum: 87E3A5649EA7C5F6

FASTA50755,448
        10         20         30         40         50         60 
SESGVGFAGC FRSMDEFHPF IEALLPHVRA FSYTWFNLQA RKRKYFKKHE KRMSKDEERA 

        70         80         90        100        110        120 
VKDELLGEKP EIKQKWASRL LAKLRKDIRP EFREDFVLTI TGKKPPCCVL SNPDQKGKIR 

       130        140        150        160        170        180 
RIDCLRQADK VWRLDLVMVI LFKGIPLEST DGERLYKSPQ CSNPGLCVQP HHIGVTIKEL 

       190        200        210        220        230        240 
DLYLAYFVHT PESGQSDSSN QQGDADIKPL PNGHLSFQDC FVTSGVWNVT ELVRVSQTPV 

       250        260        270        280        290        300 
ATASGPNFSL ADLESPSYYN INQVTLGRRS ITSPPSTSST KRPKSIDDSE MESPVDDVFY 

       310        320        330        340        350        360 
PGTGRSPAAG SSQSSGWPND VDAGPASLKK SGKLDFCSAL SSQGSSPRMA FTHHPLPVLA 

       370        380        390        400        410        420 
GVRPGSPRAT ASALHFPSTS IIQQSSPYFT HPTIRYHHHH GQDSLKEFVQ FVCSDGSGQA 

       430        440        450        460        470        480 
TGQPNGSGQG KVPGSFLLPP PPPVARPVPL PMPDSKTTST APDGAALTPP SPSFTTTGAS 

       490        500 
SANRFVSIGS RDGNFLNIPQ QSQSWFL

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6 EMBL AAH90626.1.
Tissue: Brain EMBL AAH90626.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC090626 mRNA. Translation: AAH90626.1.
IPIIPI00985966.
RefSeqNP_001075450.1. NM_001081981.1.
UniGeneMm.9394.

3D structure databases

ModBaseSearch...

Proteomic databases

PRIDEQ5CZY4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID18032.
KEGGmmu:18032.

Organism-specific databases

CTD4784.
MGIMGI:97311. Nfix.

Phylogenomic databases

HOGENOMHOG000013028.
HOVERGENHBG006561.
InParanoidQ5CZY4.
KOK09171.

Gene expression databases

ArrayExpressQ5CZY4.
BgeeQ5CZY4.
GenevestigatorQ5CZY4.

Family and domain databases

InterProIPR000647. CTF/NFI.
IPR020604. CTF/NFI_DNA-bd-dom.
IPR019739. CTF/NFI_DNA-bd_CS.
IPR019548. CTF/NFI_DNA-bd_N.
IPR003619. MAD_homology1_Dwarfin-type.
[Graphical view]
PANTHERPTHR11492. PTHR11492. 1 hit.
PfamPF00859. CTF_NFI. 1 hit.
PF03165. MH1. 1 hit.
PF10524. NfI_DNAbd_pre-N. 1 hit.
[Graphical view]
SMARTSM00523. DWA. 1 hit.
[Graphical view]
PROSITEPS00349. CTF_NFI_1. 1 hit.
PS51080. CTF_NFI_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio293113.
SOURCESearch...

Entry information

Entry nameQ5CZY4_MOUSE
AccessionPrimary (citable) accession number: Q5CZY4
Entry history
Integrated into UniProtKB/TrEMBL: March 29, 2005
Last sequence update: March 29, 2005
Last modified: May 29, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info