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Protein
Submitted name:

Trp63 protein

Gene

Trp63

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Trp63 proteinImported
Gene namesi
Name:Trp63Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1330810. Trp63.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ5CZX0.

Expressioni

Gene expression databases

GenevisibleiQ5CZX0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000110965.

Structurei

3D structure databases

ProteinModelPortaliQ5CZX0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini443 – 50967SAM (sterile alpha motif)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the p53 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IGE4. Eukaryota.
ENOG410XV9W. LUCA.
HOVERGENiHBG005201.
KOiK10149.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
2.60.40.720. 1 hit.
4.10.170.10. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR012346. p53/RUNT-type_TF_DNA-bd.
IPR011615. p53_DNA-bd.
IPR010991. p53_tetrameristn.
IPR002117. p53_tumour_suppressor.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR032645. Tp63.
[Graphical view]
PANTHERiPTHR11447. PTHR11447. 2 hits.
PTHR11447:SF8. PTHR11447:SF8. 2 hits.
PfamiPF00870. P53. 1 hit.
PF07710. P53_tetramer. 1 hit.
PF07647. SAM_2. 1 hit.
[Graphical view]
PRINTSiPR00386. P53SUPPRESSR.
SMARTiSM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47719. SSF47719. 1 hit.
SSF47769. SSF47769. 1 hit.
SSF49417. SSF49417. 1 hit.
PROSITEiPS00348. P53. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5CZX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYLENNAQT QFSEPQYTNL GLLNSMDQQI QNGSSSTSPY NTDHAQNSVT
60 70 80 90 100
APSPYAQPSS TFDALSPSPA IPSNTDYPGP HSFDVSFQQS STAKSATWTY
110 120 130 140 150
STELKKLYCQ IAKTCPIQIK VMTPPPQGAV IRAMPVYKKA EHVTEVVKRC
160 170 180 190 200
PNHELSREFN EGQIAPPSHL IRVEGNSHAQ YVEDPITGRQ SVLVPYEPPQ
210 220 230 240 250
VGTEFTTVLY NFMCNSSCVG GMNRRPILII VTLETRDGQV LGRRCFEARI
260 270 280 290 300
CACPGRDRKA DEDSIRKQQV SDSAKNGDAF RQNTHGIQMT SIKKRRSPDD
310 320 330 340 350
ELLYLPVRGR ETYEMLLKIK ESLELMQYLP QHTIETYRQQ QQQQHQHLLQ
360 370 380 390 400
KQTSMQSQSS YGNSSPPLNK MNSMNKLPSV SQLINPQQRN ALTPTTMPEG
410 420 430 440 450
MGANIPMMGT HMPMPGDMNG LSPTQALPPP LSMPSTSHCT PPPPYPTDCS
460 470 480 490 500
IVSFLARLGC SSCLDYFTTQ GLTTIYQIEH YSIDDLASLK IPEQFRHAIW
510 520 530 540 550
KGILDHRQLH DFSSPPHLLR TPSGASTVSV GSSETRGERV IDAVRFTLRQ
560 570 580
TISFPPRDEW NDFNFDMDSR RNKQQRIKEE GE
Length:582
Mass (Da):65,329
Last modified:March 29, 2005 - v1
Checksum:iAF8D05E3249406D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC090649 mRNA. Translation: AAH90649.1.
RefSeqiNP_001120731.1. NM_001127259.1.
NP_001120732.1. NM_001127260.1.
NP_001120734.1. NM_001127262.1.
NP_001120736.1. NM_001127264.1.
NP_035771.1. NM_011641.2.
UniGeneiMm.20894.

Genome annotation databases

GeneIDi22061.
KEGGimmu:22061.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC090649 mRNA. Translation: AAH90649.1.
RefSeqiNP_001120731.1. NM_001127259.1.
NP_001120732.1. NM_001127260.1.
NP_001120734.1. NM_001127262.1.
NP_001120736.1. NM_001127264.1.
NP_035771.1. NM_011641.2.
UniGeneiMm.20894.

3D structure databases

ProteinModelPortaliQ5CZX0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000110965.

Proteomic databases

PaxDbiQ5CZX0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22061.
KEGGimmu:22061.

Organism-specific databases

CTDi22061.
MGIiMGI:1330810. Trp63.

Phylogenomic databases

eggNOGiENOG410IGE4. Eukaryota.
ENOG410XV9W. LUCA.
HOVERGENiHBG005201.
KOiK10149.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

GenevisibleiQ5CZX0. MM.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
2.60.40.720. 1 hit.
4.10.170.10. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR012346. p53/RUNT-type_TF_DNA-bd.
IPR011615. p53_DNA-bd.
IPR010991. p53_tetrameristn.
IPR002117. p53_tumour_suppressor.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR032645. Tp63.
[Graphical view]
PANTHERiPTHR11447. PTHR11447. 2 hits.
PTHR11447:SF8. PTHR11447:SF8. 2 hits.
PfamiPF00870. P53. 1 hit.
PF07710. P53_tetramer. 1 hit.
PF07647. SAM_2. 1 hit.
[Graphical view]
PRINTSiPR00386. P53SUPPRESSR.
SMARTiSM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47719. SSF47719. 1 hit.
SSF47769. SSF47769. 1 hit.
SSF49417. SSF49417. 1 hit.
PROSITEiPS00348. P53. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6Imported.
    Tissue: HeadImported.

Entry informationi

Entry nameiQ5CZX0_MOUSE
AccessioniPrimary (citable) accession number: Q5CZX0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 29, 2005
Last sequence update: March 29, 2005
Last modified: June 8, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.