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Protein
Submitted name:

Uncharacterized protein

Gene

cgd8_3330

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Initiation factorUniRule annotation

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:cgd8_3330Imported
OrganismiCryptosporidium parvum (strain Iowa II)Imported
Taxonomic identifieri353152 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
Proteomesi
  • UP000006726 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiCryptoDB:cgd8_3330.

Interactioni

Protein-protein interaction databases

STRINGi353152.XP_627228.1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2OQKX-ray1.80A1-117[»]
ProteinModelPortaliQ5CVP1.
SMRiQ5CVP1. Positions 2-127.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5CVP1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 9675S1-likeInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the eIF-1A family.UniRule annotation
Contains 1 S1-like domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG3403. Eukaryota.
COG0361. LUCA.
HOGENOMiHOG000223675.
InParanoidiQ5CVP1.
KOiK03236.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00216. aIF_1A.
InterProiIPR012340. NA-bd_OB-fold.
IPR006196. RNA-binding_domain_S1_IF1.
IPR001253. TIF_eIF-1A.
IPR018104. TIF_eIF-1A_CS.
[Graphical view]
PANTHERiPTHR21668. PTHR21668. 1 hit.
PfamiPF01176. eIF-1a. 1 hit.
[Graphical view]
ProDomiPD005579. TIF_eIF-1A. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00652. eIF1a. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00523. eIF-1A. 1 hit.
PROSITEiPS01262. IF1A. 1 hit.
PS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5CVP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKNKGKGGK NRRRGKNDSE GDKRELVFKE EGQEYGQVQR MLGNGRLDAY
60 70 80 90 100
CFDGQKRLCH IRGKMRKKVW VNPGDIVLVS LRDFQDSKGD IILKYTPDEA
110 120 130 140
RALKSKGEIP ETTKINESDI FEDGYDEVGI EFDETEGVDI EDI
Length:143
Mass (Da):16,328
Last modified:April 12, 2005 - v1
Checksum:i1310DB90E8BB6722
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000003 Genomic DNA. Translation: EAK89502.1.
RefSeqiXP_627228.1. XM_627228.1.

Genome annotation databases

EnsemblProtistsiEAK89502; EAK89502; cgd8_3330.
GeneIDi3374252.
KEGGicpv:cgd8_3330.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000003 Genomic DNA. Translation: EAK89502.1.
RefSeqiXP_627228.1. XM_627228.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2OQKX-ray1.80A1-117[»]
ProteinModelPortaliQ5CVP1.
SMRiQ5CVP1. Positions 2-127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi353152.XP_627228.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAK89502; EAK89502; cgd8_3330.
GeneIDi3374252.
KEGGicpv:cgd8_3330.

Organism-specific databases

EuPathDBiCryptoDB:cgd8_3330.

Phylogenomic databases

eggNOGiKOG3403. Eukaryota.
COG0361. LUCA.
HOGENOMiHOG000223675.
InParanoidiQ5CVP1.
KOiK03236.

Miscellaneous databases

EvolutionaryTraceiQ5CVP1.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00216. aIF_1A.
InterProiIPR012340. NA-bd_OB-fold.
IPR006196. RNA-binding_domain_S1_IF1.
IPR001253. TIF_eIF-1A.
IPR018104. TIF_eIF-1A_CS.
[Graphical view]
PANTHERiPTHR21668. PTHR21668. 1 hit.
PfamiPF01176. eIF-1a. 1 hit.
[Graphical view]
ProDomiPD005579. TIF_eIF-1A. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00652. eIF1a. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00523. eIF-1A. 1 hit.
PROSITEiPS01262. IF1A. 1 hit.
PS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Iowa IIImported.
  2. "Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A."
    Dong A., Lew J., Zhao Y., Hassanali A., Lin L., Qiu W., Brokx S.J., Wasney G., Vedadi M., Kozieradzki I., Bochkarev A., Edwards A.M., Arrowsmith C.H., Weigelt J., Sundstrom M., Hui R., Altamentova S.
    Submitted (JAN-2007) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 1-117.

Entry informationi

Entry nameiQ5CVP1_CRYPI
AccessioniPrimary (citable) accession number: Q5CVP1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: March 16, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.