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Q5CU85

- Q5CU85_CRYPI

UniProt

Q5CU85 - Q5CU85_CRYPI

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Protein

DNA ligase

Gene
cgd3_3820
Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:cgd3_3820Imported
OrganismiCryptosporidium parvum (strain Iowa II)Imported
Taxonomic identifieri353152 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
ProteomesiUP000006726: Chromosome 3

Organism-specific databases

EuPathDBiCryptoDB:cgd3_3820.

Interactioni

Protein-protein interaction databases

STRINGi5807.cgd3_3820.

Structurei

3D structure databases

ProteinModelPortaliQ5CU85.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036006.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5CU85-1 [UniParc]FASTAAdd to Basket

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MTGKCLDSLF NEEDDMNEII ETEDSIIDSK ETIINEKISL DSILGRELMS    50
NVKKDEKRSK KIKLDSNIQQ KLSFNFGTGN TPSSVNKSKP TKLEKVPENE 100
ESGDSCTKNG SESLSKKIKP SNAGLFSPFS INITTGDEDI QSPMFDPCNI 150
SKEKIMAKGK SNSILFSVLT DAFSRIEQLK GSGSGSKKGC IVILANLFRL 200
IIHHNPSDLI DAVYICMNKV APDYEGKESG VGDSILIKCI SESSDKSEKR 250
IKEDQISGKF EDLGEIAAIC KKQMRLLFEP QRLTIHDVYS DLYSLTEITG 300
KQSQQLKKDK IKKLLVSGKQ DEVKYIVRFL QGRLRIGIQQ TTVYQALASA 350
FVLTKNIPGD NLASFSDYRL AKNEKKYKNL QELDCEILEM ETSLRSSLCQ 400
LPNIEKIINV AIQGASSDEI SAKCKLTTGI PCEPMLARPT KGIQDVLNRF 450
ENFLFTAEYK YDGERAQIHV YKDKSNKRVI KIFTRNLESA TDRYPDLIQY 500
LNQSLNSSVE DCILDSEVVA YSKSEDKILP FQVLSTRKRK NVAFDDIQIQ 550
ICLMLFDCMG FNGESLLKKS LFERRQYLRK CINEGQSEYI KFTTSTETNK 600
LDHLDSFLSE SIENNCEGLM VKTLHDNASY EPSKRSLNWL KIKKDYVDGL 650
TDSIDVVPIA ACYGKGKRNG VFGTFLLAVY NTEEEVYETV CKAGTGFSDE 700
ILQSLYTSLK DHIIAEGAPK SYYKFDSSGQ LSSLKQDVWF EPKFVWEVKG 750
ADLSLSPVHT AAIGTIDENR GIGLRFPRFI RIRDDKSPEQ ATSSIQIMEM 800
YNSQLITNNT KNETNFSDDQ FQEDD 825
Length:825
Mass (Da):93,061
Last modified:April 12, 2005 - v1
Checksum:i1B9BD6A63ABAF8CA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAEE01000004 Genomic DNA. Translation: EAK88972.1.
RefSeqiXP_626929.1. XM_626929.1.

Genome annotation databases

GeneIDi3373851.
KEGGicpv:cgd3_3820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAEE01000004 Genomic DNA. Translation: EAK88972.1 .
RefSeqi XP_626929.1. XM_626929.1.

3D structure databases

ProteinModelPortali Q5CU85.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5807.cgd3_3820.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3373851.
KEGGi cpv:cgd3_3820.

Organism-specific databases

EuPathDBi CryptoDB:cgd3_3820.

Phylogenomic databases

HOGENOMi HOG000036006.
KOi K10747.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Iowa II.

Entry informationi

Entry nameiQ5CU85_CRYPI
AccessioniPrimary (citable) accession number: Q5CU85
Entry historyi
Integrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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