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Q5CU85

- Q5CU85_CRYPI

UniProt

Q5CU85 - Q5CU85_CRYPI

Protein

DNA ligase

Gene

cgd3_3820

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (12 Apr 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:cgd3_3820Imported
    OrganismiCryptosporidium parvum (strain Iowa II)Imported
    Taxonomic identifieri353152 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
    ProteomesiUP000006726: Chromosome 3

    Organism-specific databases

    EuPathDBiCryptoDB:cgd3_3820.

    Interactioni

    Protein-protein interaction databases

    STRINGi5807.cgd3_3820.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5CU85.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000036006.
    KOiK10747.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5CU85-1 [UniParc]FASTAAdd to Basket

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    MTGKCLDSLF NEEDDMNEII ETEDSIIDSK ETIINEKISL DSILGRELMS    50
    NVKKDEKRSK KIKLDSNIQQ KLSFNFGTGN TPSSVNKSKP TKLEKVPENE 100
    ESGDSCTKNG SESLSKKIKP SNAGLFSPFS INITTGDEDI QSPMFDPCNI 150
    SKEKIMAKGK SNSILFSVLT DAFSRIEQLK GSGSGSKKGC IVILANLFRL 200
    IIHHNPSDLI DAVYICMNKV APDYEGKESG VGDSILIKCI SESSDKSEKR 250
    IKEDQISGKF EDLGEIAAIC KKQMRLLFEP QRLTIHDVYS DLYSLTEITG 300
    KQSQQLKKDK IKKLLVSGKQ DEVKYIVRFL QGRLRIGIQQ TTVYQALASA 350
    FVLTKNIPGD NLASFSDYRL AKNEKKYKNL QELDCEILEM ETSLRSSLCQ 400
    LPNIEKIINV AIQGASSDEI SAKCKLTTGI PCEPMLARPT KGIQDVLNRF 450
    ENFLFTAEYK YDGERAQIHV YKDKSNKRVI KIFTRNLESA TDRYPDLIQY 500
    LNQSLNSSVE DCILDSEVVA YSKSEDKILP FQVLSTRKRK NVAFDDIQIQ 550
    ICLMLFDCMG FNGESLLKKS LFERRQYLRK CINEGQSEYI KFTTSTETNK 600
    LDHLDSFLSE SIENNCEGLM VKTLHDNASY EPSKRSLNWL KIKKDYVDGL 650
    TDSIDVVPIA ACYGKGKRNG VFGTFLLAVY NTEEEVYETV CKAGTGFSDE 700
    ILQSLYTSLK DHIIAEGAPK SYYKFDSSGQ LSSLKQDVWF EPKFVWEVKG 750
    ADLSLSPVHT AAIGTIDENR GIGLRFPRFI RIRDDKSPEQ ATSSIQIMEM 800
    YNSQLITNNT KNETNFSDDQ FQEDD 825
    Length:825
    Mass (Da):93,061
    Last modified:April 12, 2005 - v1
    Checksum:i1B9BD6A63ABAF8CA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAEE01000004 Genomic DNA. Translation: EAK88972.1.
    RefSeqiXP_626929.1. XM_626929.1.

    Genome annotation databases

    GeneIDi3373851.
    KEGGicpv:cgd3_3820.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAEE01000004 Genomic DNA. Translation: EAK88972.1 .
    RefSeqi XP_626929.1. XM_626929.1.

    3D structure databases

    ProteinModelPortali Q5CU85.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5807.cgd3_3820.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3373851.
    KEGGi cpv:cgd3_3820.

    Organism-specific databases

    EuPathDBi CryptoDB:cgd3_3820.

    Phylogenomic databases

    HOGENOMi HOG000036006.
    KOi K10747.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Iowa IIImported.

    Entry informationi

    Entry nameiQ5CU85_CRYPI
    AccessioniPrimary (citable) accession number: Q5CU85
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 12, 2005
    Last sequence update: April 12, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3