ID   Q5CS64_CRYPI            Unreviewed;      1148 AA.
AC   Q5CS64;
DT   12-APR-2005, integrated into UniProtKB/TrEMBL.
DT   12-APR-2005, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Phosphoenolpyruvate carboxylase {ECO:0000313|EMBL:EAK88198.1};
GN   ORFNames=cgd5_70 {ECO:0000313|EMBL:EAK88198.1};
OS   Cryptosporidium parvum (strain Iowa II).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK88198.1, ECO:0000313|Proteomes:UP000006726};
RN   [1] {ECO:0000313|EMBL:EAK88198.1, ECO:0000313|Proteomes:UP000006726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX   PubMed=15044751; DOI=10.1126/science.1094786;
RA   Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA   Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA   Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA   Anantharaman V., Aravind L., Kapur V.;
RT   "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL   Science 304:441-445(2004).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAK88198.1}.
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DR   EMBL; AAEE01000007; EAK88198.1; -; Genomic_DNA.
DR   RefSeq; XP_625972.1; XM_625972.1.
DR   AlphaFoldDB; Q5CS64; -.
DR   STRING; 353152.Q5CS64; -.
DR   EnsemblProtists; EAK88198; EAK88198; cgd5_70.
DR   GeneID; 3373336; -.
DR   KEGG; cpv:cgd5_70; -.
DR   VEuPathDB; CryptoDB:cgd5_70; -.
DR   InParanoid; Q5CS64; -.
DR   OMA; FGWTQSR; -.
DR   OrthoDB; 355614at2759; -.
DR   Proteomes; UP000006726; Chromosome 5.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:InterPro.
DR   GO; GO:0015977; P:carbon fixation; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   Pfam; PF00311; PEPcase; 3.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   4: Predicted;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Pyruvate {ECO:0000313|EMBL:EAK88198.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006726}.
FT   ACT_SITE        781
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   1148 AA;  130836 MW;  38A076418DF5A022 CRC64;
     MSISNNDNEI KESRLFPVGF KKEFCTFLEK PQKIVSEKDV ILNKLNEPLD EDIKALELHM
     FGLVTSHWRS SRKYILHGNK QKNNIDEGVL SPSNDGVRKI FDILKLSMNF AENEDSSSLN
     QLWERIKHLD SGMLTLVVSL FNQMCMITNY AESAQRIRQC RQFEREIPSI LSESQIFSKN
     NQSPDSDIIF AHSLRVTIKK LLQAGFSKEH IYKLICEQEV DLVVTAHPTQ AQRISVIKCC
     QKIGEIMIYL DRDDLTPFEI NNAKYELQRA MAMLWNVDTL RRARPTPLDE VQNTINTIEE
     TVFSTLPTFL RKIDEILNEF GMDPLPPTKT LFKYSSWVGG DRDGNPYVTA KVTRLSVINM
     RLRACNLFLH KIEDLMYEIP IISSHEKLRE YVDNLPDIEF YIRPVSSCDT LNNSGCTTSD
     ATVGLRPFMG FIPEYELYRR ILHHVRIRLI ASRDYYLDAL NFGHSVNSET RRALAYHSTE
     QILEPLILMY NALEDYDHEI KTNFEDGHLP GTNISVPWIS ESGSVSAKLG RGLLLDVIRQ
     ISAFGLSFMR LDIRQEASKH EKAMDEICNY LEIGNYSEFS EEEKQEFLLN CLKSKRPLIP
     YRLNWSKETT EILDTFYECS HLGAEALGSY IISMCMKPSD ILCVHVFQKE YFSTISADSE
     FHAEIHDLNK FIKRRSSSIS SNCNSNGVVN VEVSNVDNND SRQNGGISPS INDSPKSSAA
     ILSSIASKRM RVVPLLETVE ALNNAEKTLE TLLSNEWYLN YVKTVDGGIV EVMIGYSDSS
     KDGGRLTSGW QLYNAQERLS NIARRFGVEM VFFHGRGGSI GRGGGPQHLA ILSQPPNTIT
     SLMRITVQGE AITQSFGLSE IAFKTWEIYC SAILESRITA LDIPNNNQCE PNGNLGYGTK
     VKESWRELLD QMSDISMKEY RKIVFGEGNS DFTSDEFVAY FRSVTPEKEI SELNLGSRPS
     KRKSGGIETL RAIPWVFAWT QIRSHLPVWL GLSAALEEMK KQNKLNLVTE MYENWPFVKS
     FFDLVSMILL KADVHIFELY NRILAPPDLQ KIGDLLISKL KDTIKLVMEV TKEKQLLDSD
     FVTRKAILLR FSWLAPCHLV QIECINRRRK ILCSSVNSSE INEIELSKIE NALKISIQSI
     SAGMKFTG
//