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Q5CQ21

- Q5CQ21_CRYPI

UniProt

Q5CQ21 - Q5CQ21_CRYPI

Protein

Thymidine kinase

Gene

cgd5_4440

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (12 Apr 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    ORF Names:cgd5_4440Imported
    OrganismiCryptosporidium parvum (strain Iowa II)Imported
    Taxonomic identifieri353152 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
    ProteomesiUP000006726: Chromosome 5

    Organism-specific databases

    EuPathDBiCryptoDB:cgd5_4440.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5CQ21.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000076391.
    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q5CQ21-1 [UniParc]FASTAAdd to Basket

    « Hide

    DWKYFNKMAK LYFYYSAMNA GKSTVLLQSS FNYQERGMKT ILFTISKDCR    50
    FEEGSICSRI GLSEKAHTFT PDLKLLDIIN QENNKEKIDC VLVDESQFLT 100
    KFQVRELCIV VDKLNIPVLC YGLRTDFKGN LFEGSKYLLA WADKLTEIKT 150
    ICRCGKKATM TIRLNSNGEP VFSGEQILIG DNSIYTSVCR KHHIINCEEY 200
    NF 202
    Length:202
    Mass (Da):23,313
    Last modified:April 12, 2005 - v1
    Checksum:i91A9ABEA061E3263
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAEE01000010 Genomic DNA. Translation: EAK87600.1.
    RefSeqiXP_625605.1. XM_625605.1.

    Genome annotation databases

    GeneIDi3372560.
    KEGGicpv:cgd5_4440.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAEE01000010 Genomic DNA. Translation: EAK87600.1 .
    RefSeqi XP_625605.1. XM_625605.1.

    3D structure databases

    ProteinModelPortali Q5CQ21.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3372560.
    KEGGi cpv:cgd5_4440.

    Organism-specific databases

    EuPathDBi CryptoDB:cgd5_4440.

    Phylogenomic databases

    HOGENOMi HOG000076391.
    KOi K00857.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Iowa IIImported.

    Entry informationi

    Entry nameiQ5CQ21_CRYPI
    AccessioniPrimary (citable) accession number: Q5CQ21
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 12, 2005
    Last sequence update: April 12, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3