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Protein

Thymidine kinase

Gene

cgd5_4440

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
ORF Names:cgd5_4440Imported
OrganismiCryptosporidium parvum (strain Iowa II)Imported
Taxonomic identifieri353152 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
ProteomesiUP000006726 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiCryptoDB:cgd5_4440.

Structurei

3D structure databases

ProteinModelPortaliQ5CQ21.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076391.
InParanoidiQ5CQ21.
KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5CQ21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DWKYFNKMAK LYFYYSAMNA GKSTVLLQSS FNYQERGMKT ILFTISKDCR
60 70 80 90 100
FEEGSICSRI GLSEKAHTFT PDLKLLDIIN QENNKEKIDC VLVDESQFLT
110 120 130 140 150
KFQVRELCIV VDKLNIPVLC YGLRTDFKGN LFEGSKYLLA WADKLTEIKT
160 170 180 190 200
ICRCGKKATM TIRLNSNGEP VFSGEQILIG DNSIYTSVCR KHHIINCEEY

NF
Length:202
Mass (Da):23,313
Last modified:April 11, 2005 - v1
Checksum:i91A9ABEA061E3263
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000010 Genomic DNA. Translation: EAK87600.1.
RefSeqiXP_625605.1. XM_625605.1.

Genome annotation databases

GeneIDi3372560.
KEGGicpv:cgd5_4440.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000010 Genomic DNA. Translation: EAK87600.1.
RefSeqiXP_625605.1. XM_625605.1.

3D structure databases

ProteinModelPortaliQ5CQ21.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3372560.
KEGGicpv:cgd5_4440.

Organism-specific databases

EuPathDBiCryptoDB:cgd5_4440.

Phylogenomic databases

HOGENOMiHOG000076391.
InParanoidiQ5CQ21.
KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Iowa IIImported.

Entry informationi

Entry nameiQ5CQ21_CRYPI
AccessioniPrimary (citable) accession number: Q5CQ21
Entry historyi
Integrated into UniProtKB/TrEMBL: April 11, 2005
Last sequence update: April 11, 2005
Last modified: March 31, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.